DK0515540T3 - Derivat af beta-phenylisoserin, dets fremstilling og anvendelse - Google Patents
Derivat af beta-phenylisoserin, dets fremstilling og anvendelseInfo
- Publication number
- DK0515540T3 DK0515540T3 DK91905054.2T DK91905054T DK0515540T3 DK 0515540 T3 DK0515540 T3 DK 0515540T3 DK 91905054 T DK91905054 T DK 91905054T DK 0515540 T3 DK0515540 T3 DK 0515540T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- preparation
- phenylisoserine
- derivative
- beta
- Prior art date
Links
- RZARFIRJROUVLM-GVHYBUMESA-N (3r)-3-amino-2-hydroxy-3-phenylpropanoic acid Chemical class OC(=O)C(O)[C@H](N)C1=CC=CC=C1 RZARFIRJROUVLM-GVHYBUMESA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Liquid Developers In Electrophotography (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9002099A FR2658510B1 (fr) | 1990-02-21 | 1990-02-21 | Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0515540T3 true DK0515540T3 (da) | 1994-08-15 |
Family
ID=9393962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91905054.2T DK0515540T3 (da) | 1990-02-21 | 1991-02-20 | Derivat af beta-phenylisoserin, dets fremstilling og anvendelse |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5359124A (cs) |
| EP (1) | EP0515540B1 (cs) |
| JP (1) | JP3057097B2 (cs) |
| KR (1) | KR100197481B1 (cs) |
| AT (1) | ATE108176T1 (cs) |
| AU (1) | AU642717B2 (cs) |
| CA (1) | CA2071983C (cs) |
| CZ (1) | CZ279656B6 (cs) |
| DE (1) | DE69102762T2 (cs) |
| DK (1) | DK0515540T3 (cs) |
| ES (1) | ES2056639T3 (cs) |
| FI (1) | FI111247B (cs) |
| FR (1) | FR2658510B1 (cs) |
| HU (1) | HU209615B (cs) |
| IE (1) | IE64397B1 (cs) |
| IL (1) | IL97277A (cs) |
| NO (1) | NO179865C (cs) |
| PT (1) | PT96849B (cs) |
| RU (1) | RU2074172C1 (cs) |
| SK (1) | SK278304B6 (cs) |
| WO (1) | WO1991013053A1 (cs) |
| YU (1) | YU48671B (cs) |
| ZA (1) | ZA911211B (cs) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5939561A (en) * | 1992-03-10 | 1999-08-17 | Rhone-Poulence Rorer S.A. | Process for the preparation of β-phenylisoserine and β-lactam and their analogues |
| FR2688499B1 (fr) * | 1992-03-10 | 1994-05-06 | Rhone Poulenc Rorer Sa | Procede de preparation de la beta-phenylisoserine et de ses analogues. |
| CA2130578A1 (en) * | 1992-04-17 | 1993-10-28 | Geewananda P. Gunawardana | Taxol derivatives |
| MX9307777A (es) | 1992-12-15 | 1994-07-29 | Upjohn Co | 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. |
| CA2161328A1 (en) * | 1993-06-11 | 1994-12-22 | Robert C. Kelly | Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them |
| IL112412A (en) * | 1994-01-28 | 2000-02-29 | Upjohn Co | Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them |
| US5580899A (en) * | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
| US6051600A (en) * | 1995-09-12 | 2000-04-18 | Mayhew; Eric | Liposomal hydrolysis-promoting hydrophobic taxane derivatives |
| US6107332A (en) | 1995-09-12 | 2000-08-22 | The Liposome Company, Inc. | Hydrolysis-promoting hydrophobic taxane derivatives |
| WO2013188763A1 (en) | 2012-06-15 | 2013-12-19 | The Brigham And Women's Hospital, Inc. | Compositions for treating cancer and methods for making the same |
| BR112016022499A2 (pt) | 2014-04-03 | 2017-08-15 | Invictus Oncology Pvt Ltd | Produtos terapêuticos combinatórios supramoleculares |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1108180A (en) * | 1976-07-21 | 1981-09-01 | Hamao Umezawa | Analogs of bestatin |
| FR2629819B1 (fr) * | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| US5175315A (en) * | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| FR2662441B1 (fr) * | 1990-05-22 | 1992-10-23 | Rhone Poulenc Sante | Procede de preparation enantioselective de derives de la phenylisoserine. |
| FR2662440B1 (fr) * | 1990-05-22 | 1992-07-31 | Rhone Poulenc Sante | Procede de preparation stereoselective de derives de la phenylisoserine. |
-
1990
- 1990-02-21 FR FR9002099A patent/FR2658510B1/fr not_active Expired - Lifetime
-
1991
- 1991-02-19 IL IL9727791A patent/IL97277A/en not_active IP Right Cessation
- 1991-02-19 ZA ZA911211A patent/ZA911211B/xx unknown
- 1991-02-20 HU HU9202667A patent/HU209615B/hu unknown
- 1991-02-20 US US07/920,508 patent/US5359124A/en not_active Expired - Lifetime
- 1991-02-20 CA CA002071983A patent/CA2071983C/fr not_active Expired - Lifetime
- 1991-02-20 EP EP91905054A patent/EP0515540B1/fr not_active Expired - Lifetime
- 1991-02-20 CZ CS91438A patent/CZ279656B6/cs not_active IP Right Cessation
- 1991-02-20 SK SK438-91A patent/SK278304B6/sk not_active IP Right Cessation
- 1991-02-20 ES ES91905054T patent/ES2056639T3/es not_active Expired - Lifetime
- 1991-02-20 DK DK91905054.2T patent/DK0515540T3/da active
- 1991-02-20 WO PCT/FR1991/000132 patent/WO1991013053A1/fr not_active Ceased
- 1991-02-20 AU AU73453/91A patent/AU642717B2/en not_active Expired
- 1991-02-20 IE IE58691A patent/IE64397B1/en not_active IP Right Cessation
- 1991-02-20 RU SU915053004A patent/RU2074172C1/ru active
- 1991-02-20 KR KR1019920701998A patent/KR100197481B1/ko not_active Expired - Lifetime
- 1991-02-20 DE DE69102762T patent/DE69102762T2/de not_active Expired - Lifetime
- 1991-02-20 JP JP3505196A patent/JP3057097B2/ja not_active Expired - Lifetime
- 1991-02-20 AT AT91905054T patent/ATE108176T1/de not_active IP Right Cessation
- 1991-02-21 YU YU31191A patent/YU48671B/sh unknown
- 1991-02-21 PT PT96849A patent/PT96849B/pt not_active IP Right Cessation
-
1992
- 1992-08-17 FI FI923679A patent/FI111247B/fi active
- 1992-08-18 NO NO923226A patent/NO179865C/no not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE172968T1 (de) | Substituierte azadioxacycloalkene und ihre verwendung als fungizide | |
| DE69213451D1 (de) | Fluoralkoxybenzylaminoderivate stickstoffhaltiger heterocyclen | |
| NO962286D0 (no) | N-substituerte azabicykloalkanderivater som neuroleptika etc. | |
| NO924310L (no) | Nevrobeskyttende indolon- og beslektede derivater | |
| DK0581959T3 (da) | Anvendelse af makrolidforbindelser til øjensygdomme | |
| DK0515540T3 (da) | Derivat af beta-phenylisoserin, dets fremstilling og anvendelse | |
| DE59507755D1 (de) | Dipeptidische p-amidinobenzylamide mit n-terminalen sulfonyl- bzw. aminosulfonylresten | |
| DK0619806T3 (da) | Fremstilling af substituerede piperidiner | |
| DK0589949T3 (da) | Hidtil ukendte peptider, fremgangsmåder til fremstilling heraf og anvendelse af disse | |
| MX9303605A (es) | Derivados de azabicicloheptano n-substituidas, su obtencion y uso. | |
| ATE155129T1 (de) | Pyrazolin-, pyrazolidin- und hydrazinderivate mit wirkung gegenüber arthropoden | |
| DK0668852T3 (da) | Substituerede orthoethenylphenyleddikesyrederivater | |
| NO955278L (no) | Substituerte aryltiolalkyltiopyridiner | |
| DK0589903T3 (da) | Aminoalkylsubstituerede 5-mercaptothiazoler, deres fremstilling og anvendelse | |
| ATE138662T1 (de) | Antibiotische 7-aminonaphthazarinderivate | |
| ATE181327T1 (de) | Indolderivate | |
| SE8601344D0 (sv) | Derivat av 11-desoxi-17alfa-hydroxikortikosteron derivat av 11-desoxi-17alfa-hydroxikortikosteron | |
| ES2060401T3 (es) | Nuevos derivados de estroptograminas y su preparacion. | |
| DK0539451T3 (da) | Vinylsulfonyl-pristinamycin og dets fremstilling | |
| ATE139773T1 (de) | Neue 1-aryl-4-piperazinyl- cyclohexancarbonsäurenitrile, ihre herstellung und verwendung |