NO923226L - Nytt beta-fenylisoserinderivat, dets fremstilling og anvendelse - Google Patents
Nytt beta-fenylisoserinderivat, dets fremstilling og anvendelseInfo
- Publication number
- NO923226L NO923226L NO92923226A NO923226A NO923226L NO 923226 L NO923226 L NO 923226L NO 92923226 A NO92923226 A NO 92923226A NO 923226 A NO923226 A NO 923226A NO 923226 L NO923226 L NO 923226L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- derivative
- pct
- phenylisoserin
- new beta
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- RZARFIRJROUVLM-UHFFFAOYSA-N 3-azaniumyl-2-hydroxy-3-phenylpropanoate Chemical class OC(=O)C(O)C(N)C1=CC=CC=C1 RZARFIRJROUVLM-UHFFFAOYSA-N 0.000 title 1
- RZARFIRJROUVLM-GVHYBUMESA-N (3r)-3-amino-2-hydroxy-3-phenylpropanoic acid Chemical class OC(=O)C(O)[C@H](N)C1=CC=CC=C1 RZARFIRJROUVLM-GVHYBUMESA-N 0.000 abstract 1
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9002099A FR2658510B1 (fr) | 1990-02-21 | 1990-02-21 | Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi. |
| PCT/FR1991/000132 WO1991013053A1 (fr) | 1990-02-21 | 1991-02-20 | DERIVE DE LA β-PHENYLISOSERINE, SA PREPARATION ET SON EMPLOI |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO923226L true NO923226L (no) | 1992-08-18 |
| NO923226D0 NO923226D0 (no) | 1992-08-18 |
| NO179865B NO179865B (no) | 1996-09-23 |
| NO179865C NO179865C (no) | 1997-01-02 |
Family
ID=9393962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO923226A NO179865C (no) | 1990-02-21 | 1992-08-18 | Nytt -fenylisoserinderivat og dets fremstilling |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5359124A (no) |
| EP (1) | EP0515540B1 (no) |
| JP (1) | JP3057097B2 (no) |
| KR (1) | KR100197481B1 (no) |
| AT (1) | ATE108176T1 (no) |
| AU (1) | AU642717B2 (no) |
| CA (1) | CA2071983C (no) |
| CZ (1) | CZ279656B6 (no) |
| DE (1) | DE69102762T2 (no) |
| DK (1) | DK0515540T3 (no) |
| ES (1) | ES2056639T3 (no) |
| FI (1) | FI111247B (no) |
| FR (1) | FR2658510B1 (no) |
| HU (1) | HU209615B (no) |
| IE (1) | IE64397B1 (no) |
| IL (1) | IL97277A (no) |
| NO (1) | NO179865C (no) |
| PT (1) | PT96849B (no) |
| RU (1) | RU2074172C1 (no) |
| SK (1) | SK278304B6 (no) |
| WO (1) | WO1991013053A1 (no) |
| YU (1) | YU48671B (no) |
| ZA (1) | ZA911211B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5939561A (en) * | 1992-03-10 | 1999-08-17 | Rhone-Poulence Rorer S.A. | Process for the preparation of β-phenylisoserine and β-lactam and their analogues |
| FR2688499B1 (fr) * | 1992-03-10 | 1994-05-06 | Rhone Poulenc Rorer Sa | Procede de preparation de la beta-phenylisoserine et de ses analogues. |
| EP0639186B1 (en) * | 1992-04-17 | 1999-06-23 | Abbott Laboratories | Taxol derivatives |
| IL107950A (en) | 1992-12-15 | 2001-04-30 | Upjohn Co | b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them |
| ATE192147T1 (de) * | 1993-06-11 | 2000-05-15 | Upjohn Co | Delta 6, 7-taxolen, antineoplastische verwendung und diese enthaltende pharmazeutische zusammenstellungen |
| IL127597A (en) * | 1994-01-28 | 2003-07-31 | Upjohn Co | Iso-taxol analogs |
| US5580899A (en) | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
| US6107332A (en) | 1995-09-12 | 2000-08-22 | The Liposome Company, Inc. | Hydrolysis-promoting hydrophobic taxane derivatives |
| US6051600A (en) * | 1995-09-12 | 2000-04-18 | Mayhew; Eric | Liposomal hydrolysis-promoting hydrophobic taxane derivatives |
| EP2861256B1 (en) | 2012-06-15 | 2019-10-23 | The Brigham and Women's Hospital, Inc. | Compositions for treating cancer and methods for making the same |
| AU2015241198A1 (en) | 2014-04-03 | 2016-11-17 | Invictus Oncology Pvt. Ltd. | Supramolecular combinatorial therapeutics |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1108180A (en) * | 1976-07-21 | 1981-09-01 | Hamao Umezawa | Analogs of bestatin |
| FR2629819B1 (fr) * | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| US5175315A (en) * | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| FR2662440B1 (fr) * | 1990-05-22 | 1992-07-31 | Rhone Poulenc Sante | Procede de preparation stereoselective de derives de la phenylisoserine. |
| FR2662441B1 (fr) * | 1990-05-22 | 1992-10-23 | Rhone Poulenc Sante | Procede de preparation enantioselective de derives de la phenylisoserine. |
-
1990
- 1990-02-21 FR FR9002099A patent/FR2658510B1/fr not_active Expired - Lifetime
-
1991
- 1991-02-19 ZA ZA911211A patent/ZA911211B/xx unknown
- 1991-02-19 IL IL9727791A patent/IL97277A/en not_active IP Right Cessation
- 1991-02-20 DK DK91905054.2T patent/DK0515540T3/da active
- 1991-02-20 AU AU73453/91A patent/AU642717B2/en not_active Expired
- 1991-02-20 DE DE69102762T patent/DE69102762T2/de not_active Expired - Lifetime
- 1991-02-20 CA CA002071983A patent/CA2071983C/fr not_active Expired - Lifetime
- 1991-02-20 WO PCT/FR1991/000132 patent/WO1991013053A1/fr active IP Right Grant
- 1991-02-20 SK SK438-91A patent/SK278304B6/sk not_active IP Right Cessation
- 1991-02-20 JP JP3505196A patent/JP3057097B2/ja not_active Expired - Lifetime
- 1991-02-20 CZ CS91438A patent/CZ279656B6/cs not_active IP Right Cessation
- 1991-02-20 EP EP91905054A patent/EP0515540B1/fr not_active Expired - Lifetime
- 1991-02-20 AT AT91905054T patent/ATE108176T1/de not_active IP Right Cessation
- 1991-02-20 KR KR1019920701998A patent/KR100197481B1/ko not_active IP Right Cessation
- 1991-02-20 US US07/920,508 patent/US5359124A/en not_active Expired - Lifetime
- 1991-02-20 IE IE58691A patent/IE64397B1/en not_active IP Right Cessation
- 1991-02-20 HU HU9202667A patent/HU209615B/hu unknown
- 1991-02-20 ES ES91905054T patent/ES2056639T3/es not_active Expired - Lifetime
- 1991-02-20 RU SU915053004A patent/RU2074172C1/ru active
- 1991-02-21 PT PT96849A patent/PT96849B/pt not_active IP Right Cessation
- 1991-02-21 YU YU31191A patent/YU48671B/sh unknown
-
1992
- 1992-08-17 FI FI923679A patent/FI111247B/fi active
- 1992-08-18 NO NO923226A patent/NO179865C/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |