PT96849A - Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s) - Google Patents
Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s)Info
- Publication number
- PT96849A PT96849A PT96849A PT9684991A PT96849A PT 96849 A PT96849 A PT 96849A PT 96849 A PT96849 A PT 96849A PT 9684991 A PT9684991 A PT 9684991A PT 96849 A PT96849 A PT 96849A
- Authority
- PT
- Portugal
- Prior art keywords
- iso
- phenyl
- beta
- derivatives
- serin
- Prior art date
Links
- RZARFIRJROUVLM-GVHYBUMESA-N (3r)-3-amino-2-hydroxy-3-phenylpropanoic acid Chemical compound OC(=O)C(O)[C@H](N)C1=CC=CC=C1 RZARFIRJROUVLM-GVHYBUMESA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Liquid Developers In Electrophotography (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9002099A FR2658510B1 (fr) | 1990-02-21 | 1990-02-21 | Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT96849A true PT96849A (pt) | 1991-10-31 |
| PT96849B PT96849B (pt) | 1998-07-31 |
Family
ID=9393962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96849A PT96849B (pt) | 1990-02-21 | 1991-02-21 | Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s) |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5359124A (pt) |
| EP (1) | EP0515540B1 (pt) |
| JP (1) | JP3057097B2 (pt) |
| KR (1) | KR100197481B1 (pt) |
| AT (1) | ATE108176T1 (pt) |
| AU (1) | AU642717B2 (pt) |
| CA (1) | CA2071983C (pt) |
| CZ (1) | CZ279656B6 (pt) |
| DE (1) | DE69102762T2 (pt) |
| DK (1) | DK0515540T3 (pt) |
| ES (1) | ES2056639T3 (pt) |
| FI (1) | FI111247B (pt) |
| FR (1) | FR2658510B1 (pt) |
| HU (1) | HU209615B (pt) |
| IE (1) | IE64397B1 (pt) |
| IL (1) | IL97277A (pt) |
| NO (1) | NO179865C (pt) |
| PT (1) | PT96849B (pt) |
| RU (1) | RU2074172C1 (pt) |
| SK (1) | SK278304B6 (pt) |
| WO (1) | WO1991013053A1 (pt) |
| YU (1) | YU48671B (pt) |
| ZA (1) | ZA911211B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5939561A (en) * | 1992-03-10 | 1999-08-17 | Rhone-Poulence Rorer S.A. | Process for the preparation of β-phenylisoserine and β-lactam and their analogues |
| FR2688499B1 (fr) * | 1992-03-10 | 1994-05-06 | Rhone Poulenc Rorer Sa | Procede de preparation de la beta-phenylisoserine et de ses analogues. |
| US5352806A (en) * | 1992-04-17 | 1994-10-04 | Abbott Laboratories | Taxol derivatives |
| MX9307777A (es) | 1992-12-15 | 1994-07-29 | Upjohn Co | 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. |
| EP0982302B1 (en) * | 1993-06-11 | 2004-04-14 | PHARMACIA & UPJOHN COMPANY | Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them |
| IL127597A (en) * | 1994-01-28 | 2003-07-31 | Upjohn Co | Iso-taxol analogs |
| US5580899A (en) * | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
| US6107332A (en) | 1995-09-12 | 2000-08-22 | The Liposome Company, Inc. | Hydrolysis-promoting hydrophobic taxane derivatives |
| US6051600A (en) * | 1995-09-12 | 2000-04-18 | Mayhew; Eric | Liposomal hydrolysis-promoting hydrophobic taxane derivatives |
| CN104582732A (zh) | 2012-06-15 | 2015-04-29 | 布里格姆及妇女医院股份有限公司 | 治疗癌症的组合物及其制造方法 |
| KR20160132496A (ko) | 2014-04-03 | 2016-11-18 | 인빅터스 온콜로지 피비티. 엘티디. | 초분자 조합 치료제 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1108180A (en) * | 1976-07-21 | 1981-09-01 | Hamao Umezawa | Analogs of bestatin |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| FR2629819B1 (fr) * | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
| US5175315A (en) * | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| FR2662441B1 (fr) * | 1990-05-22 | 1992-10-23 | Rhone Poulenc Sante | Procede de preparation enantioselective de derives de la phenylisoserine. |
| FR2662440B1 (fr) * | 1990-05-22 | 1992-07-31 | Rhone Poulenc Sante | Procede de preparation stereoselective de derives de la phenylisoserine. |
-
1990
- 1990-02-21 FR FR9002099A patent/FR2658510B1/fr not_active Expired - Lifetime
-
1991
- 1991-02-19 ZA ZA911211A patent/ZA911211B/xx unknown
- 1991-02-19 IL IL9727791A patent/IL97277A/en not_active IP Right Cessation
- 1991-02-20 SK SK438-91A patent/SK278304B6/sk not_active IP Right Cessation
- 1991-02-20 CZ CS91438A patent/CZ279656B6/cs not_active IP Right Cessation
- 1991-02-20 JP JP3505196A patent/JP3057097B2/ja not_active Expired - Lifetime
- 1991-02-20 CA CA002071983A patent/CA2071983C/fr not_active Expired - Lifetime
- 1991-02-20 ES ES91905054T patent/ES2056639T3/es not_active Expired - Lifetime
- 1991-02-20 HU HU9202667A patent/HU209615B/hu unknown
- 1991-02-20 DK DK91905054.2T patent/DK0515540T3/da active
- 1991-02-20 US US07/920,508 patent/US5359124A/en not_active Expired - Lifetime
- 1991-02-20 AU AU73453/91A patent/AU642717B2/en not_active Expired
- 1991-02-20 DE DE69102762T patent/DE69102762T2/de not_active Expired - Lifetime
- 1991-02-20 RU SU915053004A patent/RU2074172C1/ru active
- 1991-02-20 KR KR1019920701998A patent/KR100197481B1/ko not_active Expired - Lifetime
- 1991-02-20 IE IE58691A patent/IE64397B1/en not_active IP Right Cessation
- 1991-02-20 EP EP91905054A patent/EP0515540B1/fr not_active Expired - Lifetime
- 1991-02-20 WO PCT/FR1991/000132 patent/WO1991013053A1/fr not_active Ceased
- 1991-02-20 AT AT91905054T patent/ATE108176T1/de not_active IP Right Cessation
- 1991-02-21 PT PT96849A patent/PT96849B/pt not_active IP Right Cessation
- 1991-02-21 YU YU31191A patent/YU48671B/sh unknown
-
1992
- 1992-08-17 FI FI923679A patent/FI111247B/fi active
- 1992-08-18 NO NO923226A patent/NO179865C/no not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LU88712I2 (fr) | TAXOTERE-Décotaxel | |
| MX9203053A (es) | Derivados de aza nor bornano. | |
| TR199902626T2 (xx) | Enflamasyon tedavisi i�in ikameli benzopiran t�revleri. | |
| BR9407239A (pt) | Azadioxacicloalquenos substituídos | |
| ATE181551T1 (de) | Taxol-derivate | |
| PT100606A (pt) | Derivados fluoroalcoxibenzilamino de heterociclos contendo azoto | |
| ATE167476T1 (de) | Substituierte 2-phenyl-3-methocypropensäurenester als fungizide mittel. | |
| EP0482410A3 (en) | Anti-microbial compounds, including substituted 2-cyclohexyl-amine derivatives and their preparation | |
| ES2086771T3 (es) | Composicion dermatologica y/o cosmetologica que contiene retinoides. | |
| PT96849A (pt) | Processo de preparacao de novos derivados da beta-fenil-iso-serina e de beta-fenil-iso-serina-(2r,2s) | |
| LV11899A (lv) | Jauni adenozina atvasinajumi to iegusanas panemiens | |
| DK0641346T3 (da) | Antibiotiske 7-aminonaphthazarinderivater | |
| NO955278L (no) | Substituerte aryltiolalkyltiopyridiner | |
| DK0713485T3 (da) | Thiocarbamoylforbindelser som mikrobicider | |
| DE69104363D1 (de) | Vinylsulfonyl pristinamycine und deren herstellung. | |
| ATE139773T1 (de) | Neue 1-aryl-4-piperazinyl- cyclohexancarbonsäurenitrile, ihre herstellung und verwendung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19910704 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19980413 |
|
| PD3A | Change of proprietorship |
Owner name: AVENTIS PHARMA, S.A. Effective date: 20011116 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20130415 |