DK0502788T3 - Trisubstituerede triaziner og pyrimidiner, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem - Google Patents

Trisubstituerede triaziner og pyrimidiner, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem

Info

Publication number
DK0502788T3
DK0502788T3 DK92400578.8T DK92400578T DK0502788T3 DK 0502788 T3 DK0502788 T3 DK 0502788T3 DK 92400578 T DK92400578 T DK 92400578T DK 0502788 T3 DK0502788 T3 DK 0502788T3
Authority
DK
Denmark
Prior art keywords
pyrimidines
processes
preparation
pharmaceutical agents
agents containing
Prior art date
Application number
DK92400578.8T
Other languages
English (en)
Inventor
Alain Pierre
Gilbert Regnier
Alain Dhainaut
Ghanem Atassi
Stephane Leonce
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0502788T3 publication Critical patent/DK0502788T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/54Three nitrogen atoms
    • C07D251/70Other substituted melamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK92400578.8T 1991-03-07 1992-03-06 Trisubstituerede triaziner og pyrimidiner, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem DK0502788T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9102710A FR2673627B1 (fr) 1991-03-07 1991-03-07 Triazines et pyrimidines trisubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.

Publications (1)

Publication Number Publication Date
DK0502788T3 true DK0502788T3 (da) 1994-09-12

Family

ID=9410429

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92400578.8T DK0502788T3 (da) 1991-03-07 1992-03-06 Trisubstituerede triaziner og pyrimidiner, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem

Country Status (13)

Country Link
US (1) US5238936A (da)
EP (1) EP0502788B1 (da)
JP (1) JPH0776216B2 (da)
AT (1) ATE105553T1 (da)
AU (1) AU643880B2 (da)
CA (1) CA2062378A1 (da)
DE (1) DE69200129T2 (da)
DK (1) DK0502788T3 (da)
ES (1) ES2056692T3 (da)
FR (1) FR2673627B1 (da)
IE (1) IE66187B1 (da)
NZ (1) NZ241867A (da)
ZA (1) ZA921702B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2664594B1 (fr) * 1990-07-11 1992-09-18 Adir Polymethylene-imines disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
AU2599992A (en) * 1991-11-12 1993-06-15 Pfizer Inc. Triazine derivatives for enhancing antitumor activity
US5387685A (en) * 1993-07-16 1995-02-07 American Cyanamid Co MDR reversal agents
EP0916668A4 (en) * 1996-07-29 2000-08-16 Banyu Pharma Co Ltd CHEMOKINE RECEPTOR ANTAGONISTS
EP1832655A3 (en) * 1997-04-30 2008-06-18 McGILL UNIVERSITY Methods for detecting and reversing resistance to macrocyclic lactone compounds
US6403308B1 (en) * 1997-04-30 2002-06-11 Mcgill University Methods for detecting and reversing resistance to macrocyclic lactone compounds
PT1183245E (pt) * 1999-04-22 2007-07-12 Lundbeck & Co As H Antagonistas selectivos de npy (y5)
US6218408B1 (en) 1999-06-30 2001-04-17 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US6989379B1 (en) 1999-04-22 2006-01-24 H. Lundbick A/S Selective NPY (Y5) antagonists
US6340683B1 (en) * 1999-04-22 2002-01-22 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (triazines)
US6222040B1 (en) 1999-06-30 2001-04-24 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US7273880B2 (en) * 1999-06-30 2007-09-25 H. Lunbeck A/S Selective NPY (Y5) antagonists
US6225330B1 (en) 1999-06-30 2001-05-01 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US6214853B1 (en) 1999-06-30 2001-04-10 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US6635633B2 (en) 2000-08-14 2003-10-21 Ortho-Pharmaceutical, Inc. Substituted pyrazoles
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US7223759B2 (en) * 2003-09-15 2007-05-29 Anadys Pharmaceuticals, Inc. Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds
JP6557674B2 (ja) * 2014-03-12 2019-08-07 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 新規クラスのミュー−オピオイド受容体アゴニスト
JP6674542B2 (ja) * 2015-07-30 2020-04-01 四川知本快車創新科技研究院有限公司Sichuan Knowledge Express Institute For Innovative Technologies Co, Ltd. 供与体と受容体との間に2つの非共役ブリッジを有する光電変換デバイス用の熱活性化遅延蛍光有機分子
US10844027B2 (en) 2015-09-16 2020-11-24 The Trustees Of Columbia University In The City Of New York Carboxylic diarylthiazepineamines as mu-opioid receptor agonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2524467A1 (fr) * 1982-03-30 1983-10-07 Adir Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2525597B1 (fr) * 1982-04-21 1985-06-07 Adir Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2544315B1 (fr) * 1983-04-12 1985-07-05 Adir Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant
CA2004211A1 (en) * 1988-11-30 1990-05-31 Masataka Syoji Piperidine derivatives and hyportensives containing the same
FR2664594B1 (fr) * 1990-07-11 1992-09-18 Adir Polymethylene-imines disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
JPH05125062A (ja) 1993-05-21
EP0502788B1 (fr) 1994-05-11
ATE105553T1 (de) 1994-05-15
ZA921702B (en) 1992-11-25
DE69200129T2 (de) 1994-12-01
IE66187B1 (en) 1995-12-13
JPH0776216B2 (ja) 1995-08-16
CA2062378A1 (fr) 1992-09-08
IE920717A1 (en) 1992-09-09
NZ241867A (en) 1993-02-25
DE69200129D1 (de) 1994-06-16
FR2673627A1 (fr) 1992-09-11
AU643880B2 (en) 1993-11-25
FR2673627B1 (fr) 1993-05-07
US5238936A (en) 1993-08-24
AU1146892A (en) 1992-09-10
ES2056692T3 (es) 1994-10-01
EP0502788A1 (fr) 1992-09-09

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