ATE105553T1 - Trisubstituierte triazine und pyrimidine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents

Trisubstituierte triazine und pyrimidine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Info

Publication number
ATE105553T1
ATE105553T1 AT9292400578T AT92400578T ATE105553T1 AT E105553 T1 ATE105553 T1 AT E105553T1 AT 9292400578 T AT9292400578 T AT 9292400578T AT 92400578 T AT92400578 T AT 92400578T AT E105553 T1 ATE105553 T1 AT E105553T1
Authority
AT
Austria
Prior art keywords
pyrimidines
preparation
pharmaceutical compositions
compositions containing
trisubstituted triazines
Prior art date
Application number
AT9292400578T
Other languages
English (en)
Inventor
Gilbert Regnier
Alain Dhainaut
Ghanem Atassi
Alain Pierre
Stephane Leonce
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE105553T1 publication Critical patent/ATE105553T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT9292400578T 1991-03-07 1992-03-06 Trisubstituierte triazine und pyrimidine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. ATE105553T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9102710A FR2673627B1 (fr) 1991-03-07 1991-03-07 Triazines et pyrimidines trisubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.

Publications (1)

Publication Number Publication Date
ATE105553T1 true ATE105553T1 (de) 1994-05-15

Family

ID=9410429

Family Applications (1)

Application Number Title Priority Date Filing Date
AT9292400578T ATE105553T1 (de) 1991-03-07 1992-03-06 Trisubstituierte triazine und pyrimidine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Country Status (13)

Country Link
US (1) US5238936A (de)
EP (1) EP0502788B1 (de)
JP (1) JPH0776216B2 (de)
AT (1) ATE105553T1 (de)
AU (1) AU643880B2 (de)
CA (1) CA2062378A1 (de)
DE (1) DE69200129T2 (de)
DK (1) DK0502788T3 (de)
ES (1) ES2056692T3 (de)
FR (1) FR2673627B1 (de)
IE (1) IE66187B1 (de)
NZ (1) NZ241867A (de)
ZA (1) ZA921702B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2664594B1 (fr) * 1990-07-11 1992-09-18 Adir Polymethylene-imines disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
US5536722A (en) * 1991-11-12 1996-07-16 Pfizer Inc. Triazine derivatives for enhancing antitumor activity
US5387685A (en) * 1993-07-16 1995-02-07 American Cyanamid Co MDR reversal agents
AU3633997A (en) * 1996-07-29 1998-02-20 Banyu Pharmaceutical Co., Ltd. Chemokine receptor antagonists
US6403308B1 (en) * 1997-04-30 2002-06-11 Mcgill University Methods for detecting and reversing resistance to macrocyclic lactone compounds
EP1832655A3 (de) * 1997-04-30 2008-06-18 McGILL UNIVERSITY Verfahren zum Erkennen und Rückgängigmachen von Resistenz gegen makrocyclische Laktonverbindungen
US6989379B1 (en) 1999-04-22 2006-01-24 H. Lundbick A/S Selective NPY (Y5) antagonists
US6340683B1 (en) 1999-04-22 2002-01-22 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (triazines)
US6218408B1 (en) 1999-06-30 2001-04-17 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
JP2002543067A (ja) * 1999-04-22 2002-12-17 シナプティック・ファーマスーティカル・コーポレーション 選択的なｎｐｙ（ｙ５）のアンタゴニスト
US7273880B2 (en) * 1999-06-30 2007-09-25 H. Lunbeck A/S Selective NPY (Y5) antagonists
US6214853B1 (en) 1999-06-30 2001-04-10 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US6222040B1 (en) 1999-06-30 2001-04-24 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US6225330B1 (en) 1999-06-30 2001-05-01 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
MXPA03001420A (es) 2000-08-14 2004-01-26 Johnson & Johnson Pirazoles sustituidos.
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) * 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US7223759B2 (en) * 2003-09-15 2007-05-29 Anadys Pharmaceuticals, Inc. Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds
JP6557674B2 (ja) * 2014-03-12 2019-08-07 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 新規クラスのミュー−オピオイド受容体アゴニスト
CN107849443B (zh) * 2015-07-30 2020-04-21 四川知本快车创新科技研究院有限公司 给体和受体之间具有两个非共轭桥的有效热激活延迟荧光有机分子及其在光电器件中的应用
WO2017049158A1 (en) 2015-09-16 2017-03-23 The Trustees Of Columbia University In The City Of New York Carboxylic diarylthiazepineamines as mu-opioid receptor agonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2524467A1 (fr) * 1982-03-30 1983-10-07 Adir Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2525597B1 (fr) * 1982-04-21 1985-06-07 Adir Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
FR2544315B1 (fr) * 1983-04-12 1985-07-05 Adir Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant
CA2004211A1 (en) * 1988-11-30 1990-05-31 Masataka Syoji Piperidine derivatives and hyportensives containing the same
FR2664594B1 (fr) * 1990-07-11 1992-09-18 Adir Polymethylene-imines disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
US5238936A (en) 1993-08-24
NZ241867A (en) 1993-02-25
ZA921702B (en) 1992-11-25
AU643880B2 (en) 1993-11-25
EP0502788B1 (de) 1994-05-11
FR2673627B1 (fr) 1993-05-07
DK0502788T3 (da) 1994-09-12
EP0502788A1 (de) 1992-09-09
AU1146892A (en) 1992-09-10
ES2056692T3 (es) 1994-10-01
JPH05125062A (ja) 1993-05-21
CA2062378A1 (fr) 1992-09-08
JPH0776216B2 (ja) 1995-08-16
DE69200129T2 (de) 1994-12-01
DE69200129D1 (de) 1994-06-16
FR2673627A1 (fr) 1992-09-11
IE920717A1 (en) 1992-09-09
IE66187B1 (en) 1995-12-13

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