DK0502119T3 - Liposfærer til kontrolleret frigivelse af substanser - Google Patents

Liposfærer til kontrolleret frigivelse af substanser

Info

Publication number
DK0502119T3
DK0502119T3 DK91901106.4T DK91901106T DK0502119T3 DK 0502119 T3 DK0502119 T3 DK 0502119T3 DK 91901106 T DK91901106 T DK 91901106T DK 0502119 T3 DK0502119 T3 DK 0502119T3
Authority
DK
Denmark
Prior art keywords
agent
phospholipid
lipospheres
liquid
suspension
Prior art date
Application number
DK91901106.4T
Other languages
Danish (da)
English (en)
Inventor
Abraham J Domb
Manoj Maniar
Original Assignee
Abraham J Domb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abraham J Domb filed Critical Abraham J Domb
Application granted granted Critical
Publication of DK0502119T3 publication Critical patent/DK0502119T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicinal Preparation (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Valve Device For Special Equipments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Lubricants (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK91901106.4T 1989-11-13 1990-11-08 Liposfærer til kontrolleret frigivelse af substanser DK0502119T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43554689A 1989-11-13 1989-11-13

Publications (1)

Publication Number Publication Date
DK0502119T3 true DK0502119T3 (da) 1996-06-03

Family

ID=23728827

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91901106.4T DK0502119T3 (da) 1989-11-13 1990-11-08 Liposfærer til kontrolleret frigivelse af substanser

Country Status (12)

Country Link
EP (1) EP0502119B1 (es)
JP (1) JP3233402B2 (es)
KR (1) KR960005137B1 (es)
AT (1) ATE133562T1 (es)
AU (1) AU655162B2 (es)
CA (1) CA2068216C (es)
DE (1) DE69025196T2 (es)
DK (1) DK0502119T3 (es)
ES (1) ES2085465T3 (es)
GR (1) GR3019716T3 (es)
WO (1) WO1991007171A1 (es)
ZA (1) ZA909088B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132677C2 (de) * 1991-10-01 1995-08-24 Braun Melsungen Ag Flüchtige Inhalationsnarkotika enthaltende Liposomen, ihre Herstellung und Verwendung
DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
CA2091152C (en) * 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
US5885486A (en) * 1993-03-05 1999-03-23 Pharmaciaand Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5785976A (en) * 1993-03-05 1998-07-28 Pharmacia & Upjohn Ab Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
CN1120809A (zh) * 1993-12-23 1996-04-17 Gff工业方向促进研究公司 增强免疫应答的方法
ATE183092T1 (de) 1995-10-28 1999-08-15 Braun Melsungen Ag Lokalanästhetika und/oder zentralanalgetika enthaltende pharmazeutische zusammensetzungen
NZ503086A (en) * 1997-08-29 2002-03-01 Upjohn Co An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes
CA2302275C (en) 1997-09-19 2009-12-08 Shire Laboratories, Inc. Solid solution beadlet
US6277413B1 (en) * 1998-07-17 2001-08-21 Skyepharma, Inc. Biodegradable compositions for the controlled release of encapsulated substances
BR9912275A (pt) * 1998-07-20 2001-04-17 Peptech Ltd Formulação de bioimplante
US8052982B2 (en) 1998-07-20 2011-11-08 Peptech Animal Health Pty Limited Bioimplant formulation comprising lecithin and stearin
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
FR2805761B1 (fr) * 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
ATE329655T1 (de) * 2001-09-06 2006-07-15 Wolfgang Dr Friedrich Verwendung eines gemisches von lidocain und prilocain, sowie mittel zur tumeszenz- lokalanästhesie
US6696490B2 (en) 2002-07-10 2004-02-24 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Slow release insect repellent compounds and process for delivering active
US20040146551A1 (en) 2002-11-01 2004-07-29 Biodelivery Sciences International, Inc. Geodate delivery vehicles
JP4601311B2 (ja) * 2004-03-12 2010-12-22 ネイチャーテクノロジー株式会社 球状粒子及びその製造方法
JP4533185B2 (ja) * 2005-02-24 2010-09-01 花王株式会社 固体脂質粒子製剤
US8101274B2 (en) 2007-06-11 2012-01-24 Spedden Richard H Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom
JP5681626B2 (ja) 2008-07-14 2015-03-11 ポリーペイド リミテッドＰｏｌｙｐｉｄ Ｌｔｄ． 徐放性薬剤キャリア組成物
CA2769878A1 (en) 2008-08-07 2010-02-11 Bioactive Surgical, Inc. Stem cell capture and immobilization coatings for medical devices and implants
WO2011007353A1 (en) 2009-07-14 2011-01-20 Polypid Ltd. Sustained-release drug carrier composition
EP2525778B1 (en) 2010-01-19 2018-08-01 Polypid Ltd. Sustained-release nucleic acid matrix compositions
PL2439188T3 (pl) 2010-09-15 2013-03-29 Selkis Sas Pochodne p-mentano-3,8-diolu i zawierające je środki odstraszające owady
WO2013171196A1 (en) * 2012-05-15 2013-11-21 Dsm Ip Assets B.V. Antifungal compositions
EP2854793B1 (fr) 2012-06-01 2021-10-27 Galderma Research & Development Nanocapsules lipidiques comprenant un rétinoide, nanodispersion et composition les contenant, leur procédé de préparation et leur utilisation en dermatologie
EP2823811A1 (en) * 2013-07-09 2015-01-14 OTC GmbH Targeted active release system comprising solid lipid nano-particles
DE102013224627A1 (de) 2013-11-29 2015-06-03 Andreas Lauterbach Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren
CN105939704A (zh) * 2013-12-04 2016-09-14 盖尔德马研究及发展公司 优选包含类维生素a的脂质微胶囊以及含有其的组合物、制造其的方法及其在皮肤病学中的用途
WO2016193588A1 (fr) 2015-05-29 2016-12-08 Galderma Research & Development Compositions comprenant au moins un principe actif disperse et des microcapsules lipidiques
WO2016203924A1 (ja) 2015-06-17 2016-12-22 臼井国際産業株式会社 燃料噴射管用鋼管およびその製造方法
CN107608422A (zh) * 2017-09-29 2018-01-19 智车优行科技（北京）有限公司 车载温度控制装置
IT201900011436A1 (it) 2019-07-10 2021-01-10 Univ Degli Studi Di Palermo Particelle micrometriche, loro metodo di preparazione e loro usi
AU2021220263A1 (en) 2020-02-13 2022-08-25 Glycoscience, S.L. 3'-ketoglycoside compound for the slow release of a volatile alcohol
WO2023057235A1 (en) 2021-10-06 2023-04-13 Glycoscience, S.L. Process for preparing 3'-ketoglycoside compounds
CA3237982A1 (en) 2021-11-30 2023-06-08 Peter William SUTTON Slow-release formulation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4945224B1 (es) * 1970-12-14 1974-12-03
AR220263A1 (es) * 1980-02-19 1980-10-15 Bago Lab Sa Procedimiento para obtener una preparacion inyectable de sulfonamida potenciada de baja irritabilidad
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
US4797288A (en) * 1984-10-05 1989-01-10 Warner-Lambert Company Novel drug delivery system
AU6021386A (en) * 1985-07-22 1987-01-29 Desoto Inc. Cosmetic comprising sustained release of perfume or pest repellant or the like
CA1338736C (fr) * 1986-12-05 1996-11-26 Roger Baurain Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation

Also Published As

Publication number Publication date
WO1991007171A1 (en) 1991-05-30
EP0502119A1 (en) 1992-09-09
KR960005137B1 (ko) 1996-04-22
CA2068216A1 (en) 1991-05-14
JP3233402B2 (ja) 2001-11-26
JPH05505338A (ja) 1993-08-12
AU6950091A (en) 1991-06-13
CA2068216C (en) 1999-04-13
DE69025196D1 (de) 1996-03-14
EP0502119B1 (en) 1996-01-31
GR3019716T3 (en) 1996-07-31
ZA909088B (en) 1991-07-31
ES2085465T3 (es) 1996-06-01
ATE133562T1 (de) 1996-02-15
AU655162B2 (en) 1994-12-08
DE69025196T2 (de) 1996-11-14
KR920703017A (ko) 1992-12-17

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