DK0496369T3 - Fremgangsmåde til fremstilling af den racemiske og optisk aktive 1,2,3,4-tetrahydroisoquinolin-3-carboxylsyre og dens precursorforbindelser - Google Patents
Fremgangsmåde til fremstilling af den racemiske og optisk aktive 1,2,3,4-tetrahydroisoquinolin-3-carboxylsyre og dens precursorforbindelserInfo
- Publication number
- DK0496369T3 DK0496369T3 DK92100996.5T DK92100996T DK0496369T3 DK 0496369 T3 DK0496369 T3 DK 0496369T3 DK 92100996 T DK92100996 T DK 92100996T DK 0496369 T3 DK0496369 T3 DK 0496369T3
- Authority
- DK
- Denmark
- Prior art keywords
- tetrahydroisoquinoline
- racemic
- preparation
- carboxylic acid
- optically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4102017 | 1991-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0496369T3 true DK0496369T3 (da) | 1996-07-29 |
Family
ID=6423604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92100996.5T DK0496369T3 (da) | 1991-01-24 | 1992-01-22 | Fremgangsmåde til fremstilling af den racemiske og optisk aktive 1,2,3,4-tetrahydroisoquinolin-3-carboxylsyre og dens precursorforbindelser |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5252738A (ja) |
| EP (1) | EP0496369B1 (ja) |
| JP (1) | JP3187905B2 (ja) |
| KR (1) | KR100225829B1 (ja) |
| AR (1) | AR247554A1 (ja) |
| AT (1) | ATE136299T1 (ja) |
| AU (1) | AU645654B2 (ja) |
| CA (1) | CA2059908C (ja) |
| DE (1) | DE59205884D1 (ja) |
| DK (1) | DK0496369T3 (ja) |
| ES (1) | ES2085497T3 (ja) |
| FI (1) | FI101963B (ja) |
| GR (1) | GR3019556T3 (ja) |
| HU (1) | HU213273B (ja) |
| IE (1) | IE74136B1 (ja) |
| MX (1) | MX9200288A (ja) |
| NO (1) | NO178763C (ja) |
| TW (1) | TW224454B (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW224454B (ja) * | 1991-01-24 | 1994-06-01 | Hoechst Ag | |
| GB2266529A (en) * | 1992-05-01 | 1993-11-03 | Merck Sharp & Dohme | Tetrahydroisoquinoline derivatives |
| WO1997017050A2 (en) * | 1995-11-09 | 1997-05-15 | Monsanto Company | An improved method for preparation of substituted tetrahydroisoquinolines |
| FR3007751A1 (fr) | 2013-06-28 | 2015-01-02 | Solvay | Melanges de sels de sodium et de leur utilisation |
| CN111254170B (zh) * | 2018-11-30 | 2023-04-28 | 浙江大学 | 一种多酶耦合制备(s)-1,2,3,4-四氢异喹啉-3-甲酸的方法 |
| CN111254180B (zh) * | 2018-11-30 | 2023-04-28 | 浙江大学 | 一种酶法拆分制备(s)-1,2,3,4-四氢异喹啉-3-甲酸的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187290A (en) * | 1985-03-22 | 1993-02-16 | E. R. Squibb & Sons, Inc. | Acylaminoalkanoyl urethanes or thiourethanes |
| US4912221A (en) * | 1988-10-27 | 1990-03-27 | Occidental Chemical Corporation | Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and precursors and preparation thereof |
| TW224454B (ja) * | 1991-01-24 | 1994-06-01 | Hoechst Ag | |
| US5236934A (en) * | 1992-08-26 | 1993-08-17 | E. I. Du Pont De Nemours And Company | 1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders |
-
1991
- 1991-08-13 TW TW080106363A patent/TW224454B/zh not_active IP Right Cessation
-
1992
- 1992-01-21 US US07/822,930 patent/US5252738A/en not_active Expired - Lifetime
- 1992-01-22 DK DK92100996.5T patent/DK0496369T3/da active
- 1992-01-22 FI FI920269A patent/FI101963B/fi active
- 1992-01-22 AR AR92321665A patent/AR247554A1/es active
- 1992-01-22 EP EP92100996A patent/EP0496369B1/de not_active Expired - Lifetime
- 1992-01-22 AT AT92100996T patent/ATE136299T1/de not_active IP Right Cessation
- 1992-01-22 DE DE59205884T patent/DE59205884D1/de not_active Expired - Lifetime
- 1992-01-22 ES ES92100996T patent/ES2085497T3/es not_active Expired - Lifetime
- 1992-01-23 MX MX9200288A patent/MX9200288A/es unknown
- 1992-01-23 JP JP00982592A patent/JP3187905B2/ja not_active Expired - Lifetime
- 1992-01-23 NO NO920313A patent/NO178763C/no not_active IP Right Cessation
- 1992-01-23 AU AU10394/92A patent/AU645654B2/en not_active Expired
- 1992-01-23 CA CA002059908A patent/CA2059908C/en not_active Expired - Lifetime
- 1992-01-23 KR KR1019920000894A patent/KR100225829B1/ko not_active IP Right Cessation
- 1992-01-23 IE IE920207A patent/IE74136B1/en not_active IP Right Cessation
- 1992-01-24 HU HU9200231A patent/HU213273B/hu unknown
-
1993
- 1993-06-15 US US08/076,772 patent/US5359074A/en not_active Expired - Lifetime
-
1996
- 1996-04-04 GR GR960400851T patent/GR3019556T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR247554A1 (es) | 1995-01-31 |
| FI920269A0 (fi) | 1992-01-22 |
| AU1039492A (en) | 1992-07-30 |
| HU213273B (en) | 1997-04-28 |
| FI101963B1 (fi) | 1998-09-30 |
| KR100225829B1 (ko) | 1999-10-15 |
| NO178763B (no) | 1996-02-19 |
| EP0496369A1 (de) | 1992-07-29 |
| GR3019556T3 (en) | 1996-07-31 |
| DE59205884D1 (de) | 1996-05-09 |
| FI920269A (fi) | 1992-07-25 |
| JP3187905B2 (ja) | 2001-07-16 |
| NO920313D0 (no) | 1992-01-23 |
| NO920313L (no) | 1992-07-27 |
| TW224454B (ja) | 1994-06-01 |
| CA2059908C (en) | 2002-09-10 |
| ES2085497T3 (es) | 1996-06-01 |
| ATE136299T1 (de) | 1996-04-15 |
| US5252738A (en) | 1993-10-12 |
| NO178763C (no) | 1996-05-29 |
| IE920207A1 (en) | 1992-07-29 |
| EP0496369B1 (de) | 1996-04-03 |
| HU9200231D0 (en) | 1992-04-28 |
| JPH04334370A (ja) | 1992-11-20 |
| US5359074A (en) | 1994-10-25 |
| FI101963B (fi) | 1998-09-30 |
| IE74136B1 (en) | 1997-07-02 |
| MX9200288A (es) | 1992-07-01 |
| HUT63835A (en) | 1993-10-28 |
| AU645654B2 (en) | 1994-01-20 |
| KR920014782A (ko) | 1992-08-25 |
| CA2059908A1 (en) | 1992-07-25 |
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