DK0489089T3 - Terapeutiske peptider - Google Patents

Terapeutiske peptider

Info

Publication number
DK0489089T3
DK0489089T3 DK90913117.9T DK90913117T DK0489089T3 DK 0489089 T3 DK0489089 T3 DK 0489089T3 DK 90913117 T DK90913117 T DK 90913117T DK 0489089 T3 DK0489089 T3 DK 0489089T3
Authority
DK
Denmark
Prior art keywords
amino acid
active site
acid residue
peptide
peptide bond
Prior art date
Application number
DK90913117.9T
Other languages
Danish (da)
English (en)
Inventor
David H Coy
Jacques-Pierre Moreau
Sun Hyuk Kim
Original Assignee
Univ Tulane
Biomeasure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane, Biomeasure Inc filed Critical Univ Tulane
Application granted granted Critical
Publication of DK0489089T3 publication Critical patent/DK0489089T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57572—Gastrin releasing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90913117.9T 1989-08-21 1990-08-17 Terapeutiske peptider DK0489089T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39716989A 1989-08-21 1989-08-21
US07/502,438 US5084555A (en) 1989-08-21 1990-03-30 An octapeptide bombesin analog

Publications (1)

Publication Number Publication Date
DK0489089T3 true DK0489089T3 (da) 1996-07-29

Family

ID=27015776

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90913117.9T DK0489089T3 (da) 1989-08-21 1990-08-17 Terapeutiske peptider

Country Status (12)

Country Link
US (1) US5084555A (es)
EP (1) EP0489089B1 (es)
JP (1) JPH04506664A (es)
AT (1) ATE139540T1 (es)
AU (1) AU648037B2 (es)
CA (1) CA2064896A1 (es)
DE (1) DE69027533T2 (es)
DK (1) DK0489089T3 (es)
ES (1) ES2090140T3 (es)
FI (1) FI920737A0 (es)
NO (1) NO302619B1 (es)
WO (1) WO1991002746A1 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877277A (en) * 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
US6218364B1 (en) 1988-06-20 2001-04-17 Scott L. Harbeson Fluorinated neurokinin A antagonists
US5767236A (en) * 1990-05-09 1998-06-16 Biomeasure, Inc. Linear therapeutic peptides
US5620959A (en) * 1990-07-31 1997-04-15 Glaxo Wellcome Inc. Bombesin antagonists
US5369094A (en) * 1990-11-29 1994-11-29 The Administrators Of The Tulane Educational Fund Polypeptide bombesin antagonists
JPH07508025A (ja) * 1992-05-08 1995-09-07 トーマス・ジェファーソン・ユニバーシティ インスリン様増殖因子（ｉｇｆ−１）類似体
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US5650395A (en) * 1995-03-13 1997-07-22 Hurel; Steven Treatment of pulmonary hypertension
FR2739553B1 (fr) * 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
US6989371B1 (en) 1996-08-16 2006-01-24 Dabur Research Foundation Bombesin analogs for treatment of cancer
GB0009918D0 (en) * 2000-04-20 2000-06-07 Rose Keith Covalent capture facilitating purification of polypeptides
EP1260229A3 (en) * 2001-05-18 2002-12-11 Sumitomo Pharmaceuticals Company, Limited Anti-autoimmune composition comprising inhibitors of growth hormone-releasing factor activity
AU2003262878A1 (en) * 2002-08-26 2004-03-11 Wisconsin Alumni Research Foundation HETEROGENEOUS FOLDAMERS CONTAINING Alpha, Beta, AND/OR Gamma-AMINO ACIDS
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US20060239923A1 (en) * 2003-01-13 2006-10-26 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US8420050B2 (en) 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7922998B2 (en) * 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
AU2004232314B2 (en) 2003-04-22 2007-11-22 Ipsen Pharma S.A.S. Peptide vectors
EP1872795A4 (en) 2005-04-21 2009-07-22 Astellas Pharma Inc THERAPEUTIC AGENT AGAINST IRRITATION SYNDROME
KR20090058553A (ko) * 2006-09-08 2009-06-09 바이엘 쉐링 파마 악티엔게젤샤프트 18ｆ 표지된 작용제에 대한 화합물 및 방법
BRPI0719956A2 (pt) * 2006-10-02 2014-04-29 Bayer Schering Pharma Ag Radiofluoração
AU2007348145A1 (en) * 2007-03-01 2008-09-04 Bayer Schering Pharma Aktiengesellschaft 18F fluoro-benzoyl labelled biological active coumpounds as diagnositic imaging agents as well as benzotriazol-1-yloxy-benzoyl, 2,5-dioxo-pyrrolidin-1-yloxy) benzoyl and trimethylammonio-benzoyl precursers
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
JP5799397B2 (ja) 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドＩｐｓｅｎ Ｂｉｏｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 癌の抑制
EP3590956A1 (en) 2008-06-12 2020-01-08 Ipsen Bioinnovation Limited Suppression of neuroendocrine diseases
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP2198878A1 (en) 2008-12-18 2010-06-23 University Of Miami Polypeptide bombesin antagonists
AU2020218272A1 (en) 2019-02-08 2021-09-02 United States Government As Represented By The Department Of Veterans Affairs Growth hormone-releasing hormone antagonists and uses thereof
KR20200134175A (ko) * 2019-05-21 2020-12-01 주식회사 아이바이오코리아 신규한 펩타이드 화합물 또는 이의 약제학적으로 허용 가능한 염
CN116333041A (zh) * 2023-04-10 2023-06-27 湖南中晟全肽生化有限公司 一种激活grp受体的多肽化合物及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207311A (en) * 1977-07-18 1980-06-10 The Salk Institute For Biological Studies Peptides having analgesic and thermoregulative properties
US4650661A (en) * 1982-09-15 1987-03-17 Aktiebolaget Hassle Enzyme inhibitors
ATE37552T1 (de) * 1982-10-18 1988-10-15 Ici Plc Peptid- und pseudopeptid-derivate.
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds

Also Published As

Publication number Publication date
CA2064896A1 (en) 1991-02-22
WO1991002746A1 (en) 1991-03-07
EP0489089A4 (en) 1992-06-24
ATE139540T1 (de) 1996-07-15
AU648037B2 (en) 1994-04-14
NO302619B1 (no) 1998-03-30
US5084555A (en) 1992-01-28
EP0489089A1 (en) 1992-06-10
AU6294090A (en) 1991-04-03
ES2090140T3 (es) 1996-10-16
DE69027533D1 (de) 1996-07-25
FI920737A0 (fi) 1992-02-20
EP0489089B1 (en) 1996-06-19
NO920678L (no) 1992-04-06
JPH04506664A (ja) 1992-11-19
DE69027533T2 (de) 1996-12-19
NO920678D0 (no) 1992-02-20

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