ATE139540T1 - Heilmittelpeptide - Google Patents

Heilmittelpeptide

Info

Publication number
ATE139540T1
ATE139540T1 AT90913117T AT90913117T ATE139540T1 AT E139540 T1 ATE139540 T1 AT E139540T1 AT 90913117 T AT90913117 T AT 90913117T AT 90913117 T AT90913117 T AT 90913117T AT E139540 T1 ATE139540 T1 AT E139540T1
Authority
AT
Austria
Prior art keywords
amino acid
active site
acid residue
peptide
peptide bond
Prior art date
Application number
AT90913117T
Other languages
English (en)
Inventor
David H Coy
Jacques-Pierre Moreau
Sun Hyuk Kim
Original Assignee
Biomeasure Inc
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomeasure Inc, Univ Tulane filed Critical Biomeasure Inc
Application granted granted Critical
Publication of ATE139540T1 publication Critical patent/ATE139540T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57572—Gastrin releasing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90913117T 1989-08-21 1990-08-17 Heilmittelpeptide ATE139540T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39716989A 1989-08-21 1989-08-21
US07/502,438 US5084555A (en) 1989-08-21 1990-03-30 An octapeptide bombesin analog

Publications (1)

Publication Number Publication Date
ATE139540T1 true ATE139540T1 (de) 1996-07-15

Family

ID=27015776

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90913117T ATE139540T1 (de) 1989-08-21 1990-08-17 Heilmittelpeptide

Country Status (12)

Country Link
US (1) US5084555A (de)
EP (1) EP0489089B1 (de)
JP (1) JPH04506664A (de)
AT (1) ATE139540T1 (de)
AU (1) AU648037B2 (de)
CA (1) CA2064896A1 (de)
DE (1) DE69027533T2 (de)
DK (1) DK0489089T3 (de)
ES (1) ES2090140T3 (de)
FI (1) FI920737A0 (de)
NO (1) NO302619B1 (de)
WO (1) WO1991002746A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877277A (en) * 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US6218364B1 (en) 1988-06-20 2001-04-17 Scott L. Harbeson Fluorinated neurokinin A antagonists
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
US5767236A (en) * 1990-05-09 1998-06-16 Biomeasure, Inc. Linear therapeutic peptides
US5620959A (en) * 1990-07-31 1997-04-15 Glaxo Wellcome Inc. Bombesin antagonists
US5369094A (en) * 1990-11-29 1994-11-29 The Administrators Of The Tulane Educational Fund Polypeptide bombesin antagonists
EP0639981A4 (de) * 1992-05-08 1995-06-28 Univ Jefferson Analoge des igf-faktors(18.01.94).
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US5650395A (en) * 1995-03-13 1997-07-22 Hurel; Steven Treatment of pulmonary hypertension
FR2739553B1 (fr) 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
US6989371B1 (en) 1996-08-16 2006-01-24 Dabur Research Foundation Bombesin analogs for treatment of cancer
GB0009918D0 (en) * 2000-04-20 2000-06-07 Rose Keith Covalent capture facilitating purification of polypeptides
US20030013637A1 (en) * 2001-05-18 2003-01-16 Hideto Ikushima Novel anti-autoimmune composition by inhibition of GRF action
AU2003262878A1 (en) * 2002-08-26 2004-03-11 Wisconsin Alumni Research Foundation HETEROGENEOUS FOLDAMERS CONTAINING Alpha, Beta, AND/OR Gamma-AMINO ACIDS
US20060239923A1 (en) * 2003-01-13 2006-10-26 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) * 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US8420050B2 (en) 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7922998B2 (en) * 2003-01-13 2011-04-12 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
AU2004232314B2 (en) 2003-04-22 2007-11-22 Ipsen Pharma S.A.S. Peptide vectors
EP1872795A4 (de) 2005-04-21 2009-07-22 Astellas Pharma Inc Therapeutisches mittel gegen reizdarmsyndrom
EP2063918B1 (de) * 2006-09-08 2014-02-26 Piramal Imaging SA Verbindungen und verfahren für 18f-markierte mittel
AU2007304508A1 (en) * 2006-10-02 2008-04-10 Bayer Schering Pharma Aktiengesellschaft Silicon derivatives for pet imaging
AU2007348145A1 (en) * 2007-03-01 2008-09-04 Bayer Schering Pharma Aktiengesellschaft 18F fluoro-benzoyl labelled biological active coumpounds as diagnositic imaging agents as well as benzotriazol-1-yloxy-benzoyl, 2,5-dioxo-pyrrolidin-1-yloxy) benzoyl and trimethylammonio-benzoyl precursers
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
US20110171191A1 (en) 2008-06-12 2011-07-14 Syntaxin Limited Suppression of neuroendocrine diseases
JP5799397B2 (ja) 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドＩｐｓｅｎ Ｂｉｏｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 癌の抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP2198878A1 (de) 2008-12-18 2010-06-23 University Of Miami Polypeptide Bombesinantagonisten
EP3920961A4 (de) 2019-02-08 2022-12-14 United States Government as represented by the Department of Veterans Affairs Wachstumshormonfreisetzende hormonantagonisten und deren verwendungen
CN114269769A (zh) * 2019-05-21 2022-04-01 韩国视角生物株式会社 新型肽化合物或其药学上可接受的盐
CN116333041A (zh) * 2023-04-10 2023-06-27 湖南中晟全肽生化有限公司 一种激活grp受体的多肽化合物及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207311A (en) * 1977-07-18 1980-06-10 The Salk Institute For Biological Studies Peptides having analgesic and thermoregulative properties
US4650661A (en) * 1982-09-15 1987-03-17 Aktiebolaget Hassle Enzyme inhibitors
EP0109142B1 (de) * 1982-10-18 1988-09-28 Imperial Chemical Industries Plc Peptid- und Pseudopeptid-Derivate
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds

Also Published As

Publication number Publication date
DE69027533T2 (de) 1996-12-19
CA2064896A1 (en) 1991-02-22
AU648037B2 (en) 1994-04-14
US5084555A (en) 1992-01-28
EP0489089A4 (en) 1992-06-24
EP0489089A1 (de) 1992-06-10
DK0489089T3 (da) 1996-07-29
NO302619B1 (no) 1998-03-30
ES2090140T3 (es) 1996-10-16
DE69027533D1 (de) 1996-07-25
FI920737A0 (fi) 1992-02-20
JPH04506664A (ja) 1992-11-19
NO920678L (no) 1992-04-06
WO1991002746A1 (en) 1991-03-07
EP0489089B1 (de) 1996-06-19
NO920678D0 (no) 1992-02-20
AU6294090A (en) 1991-04-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee