DK0483204T3 - Fremgangsmåde til fremstilling af 2,5-diamino-4,6-dichlorpyrimidin - Google Patents

Fremgangsmåde til fremstilling af 2,5-diamino-4,6-dichlorpyrimidin

Info

Publication number
DK0483204T3
DK0483204T3 DK90910799.7T DK90910799T DK0483204T3 DK 0483204 T3 DK0483204 T3 DK 0483204T3 DK 90910799 T DK90910799 T DK 90910799T DK 0483204 T3 DK0483204 T3 DK 0483204T3
Authority
DK
Denmark
Prior art keywords
pct
diamino
dichloropyrimidine
preparation
sec
Prior art date
Application number
DK90910799.7T
Other languages
Danish (da)
English (en)
Inventor
John Hanson
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Application granted granted Critical
Publication of DK0483204T3 publication Critical patent/DK0483204T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DK90910799.7T 1989-07-21 1990-07-19 Fremgangsmåde til fremstilling af 2,5-diamino-4,6-dichlorpyrimidin DK0483204T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898916698A GB8916698D0 (en) 1989-07-21 1989-07-21 Novel process

Publications (1)

Publication Number Publication Date
DK0483204T3 true DK0483204T3 (da) 1995-08-14

Family

ID=10660401

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90910799.7T DK0483204T3 (da) 1989-07-21 1990-07-19 Fremgangsmåde til fremstilling af 2,5-diamino-4,6-dichlorpyrimidin

Country Status (12)

Country Link
US (1) US5216161A (fr)
EP (1) EP0483204B1 (fr)
JP (1) JPH04506802A (fr)
KR (1) KR927003544A (fr)
AT (1) ATE123026T1 (fr)
AU (1) AU634564B2 (fr)
CA (1) CA2063827A1 (fr)
DE (1) DE69019749T2 (fr)
DK (1) DK0483204T3 (fr)
ES (1) ES2074577T3 (fr)
GB (1) GB8916698D0 (fr)
WO (1) WO1991001310A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
SK279618B6 (sk) * 1992-01-22 1999-01-11 Lonza A.G. (Dir.:Basel) N-5-chránené 2,5-diamino-4,6-dichlórpyrimidíny a s
JP3305357B2 (ja) * 1992-05-21 2002-07-22 東芝機械株式会社 耐食・耐摩耗性に優れた合金およびその製造方法ならびにその合金製造用材料
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
GB9408270D0 (en) * 1994-04-26 1994-06-15 Zeneca Ltd Chemical process
CA2145928C (fr) * 1994-04-27 2007-10-09 Gerhard Stucky N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide; methode de preparation
US6018045A (en) * 1995-01-30 2000-01-25 Zeneca Limited Process for preparing 4,6-dichloro-pyrimidine
AT402818B (de) * 1995-06-02 1997-09-25 Chemie Linz Gmbh Verfahren zur herstellung von reinem 4,6-dichlorpyrimidin
DE59905679D1 (de) 1998-10-30 2003-06-26 Lonza Ag Verfahren zur herstellung von 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]-cyclopent-2-enylmethanolen
DK1124805T3 (da) * 1998-10-30 2003-09-15 Lonza Ag Fremgangsmåde til fremstilling af 4-[(2',5'-diamino-6'-halogenpyrimidin-4'-yl)amino]cyclopent-2-enylmethanoler
DE59907401D1 (de) * 1998-12-21 2003-11-20 Lonza Ag Verfahren zur Herstellung von 2,5-Diamino-4,6-dihalogenpyrimidinen
WO2011101861A1 (fr) 2010-01-29 2011-08-25 Msn Laboratories Limited Procédé de préparation d'inhibiteurs de la dpp-iv
DE102019007519A1 (de) 2019-10-29 2021-04-29 Gomez Cao Innovations & Inventions, S.L. Eine Flasche oder Vorform für eine Flasche und ein Verschluss für eine Flasche

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH558137A (de) * 1971-05-17 1975-01-31 Ciba Geigy Ag Mittel zur beeinflussung des pflanzenwachstums.

Also Published As

Publication number Publication date
EP0483204A1 (fr) 1992-05-06
JPH04506802A (ja) 1992-11-26
ES2074577T3 (es) 1995-09-16
DE69019749T2 (de) 1995-11-23
AU6036490A (en) 1991-02-22
GB8916698D0 (en) 1989-09-06
AU634564B2 (en) 1993-02-25
US5216161A (en) 1993-06-01
DE69019749D1 (de) 1995-06-29
ATE123026T1 (de) 1995-06-15
KR927003544A (ko) 1992-12-18
EP0483204B1 (fr) 1995-05-24
WO1991001310A1 (fr) 1991-02-07
CA2063827A1 (fr) 1991-01-22

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