DK0472501T3 - Codeinsalt af en substitueret carboxylsyre, fremgangsmåde til dets fremstilling, dets anvendelse samt farmaceutiske præparater - Google Patents
Codeinsalt af en substitueret carboxylsyre, fremgangsmåde til dets fremstilling, dets anvendelse samt farmaceutiske præparaterInfo
- Publication number
- DK0472501T3 DK0472501T3 DK91810645.1T DK91810645T DK0472501T3 DK 0472501 T3 DK0472501 T3 DK 0472501T3 DK 91810645 T DK91810645 T DK 91810645T DK 0472501 T3 DK0472501 T3 DK 0472501T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- well
- carboxylic acid
- salt
- pharmaceutical preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
- C07D489/04—Salts; Organic complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Carbon And Carbon Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH273590 | 1990-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0472501T3 true DK0472501T3 (da) | 1996-05-28 |
Family
ID=4240432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK91810645.1T DK0472501T3 (da) | 1990-08-23 | 1991-08-14 | Codeinsalt af en substitueret carboxylsyre, fremgangsmåde til dets fremstilling, dets anvendelse samt farmaceutiske præparater |
Country Status (20)
Country | Link |
---|---|
US (1) | US5190947A (ru) |
EP (1) | EP0472501B1 (ru) |
JP (1) | JPH04257587A (ru) |
KR (1) | KR920004391A (ru) |
AT (1) | ATE137753T1 (ru) |
AU (1) | AU652951B2 (ru) |
CA (1) | CA2049649A1 (ru) |
DE (1) | DE59107784D1 (ru) |
DK (1) | DK0472501T3 (ru) |
ES (1) | ES2086515T3 (ru) |
FI (1) | FI96421C (ru) |
GR (1) | GR3019872T3 (ru) |
HU (1) | HU209308B (ru) |
IE (1) | IE72479B1 (ru) |
IL (1) | IL99213A (ru) |
NO (1) | NO179175C (ru) |
NZ (1) | NZ239495A (ru) |
PT (1) | PT98731B (ru) |
TW (1) | TW225536B (ru) |
ZA (1) | ZA916642B (ru) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0498011T3 (da) * | 1991-02-07 | 1995-07-03 | Heumann Pharma Gmbh & Co | Nye salte af 2-(2,6-dichloranilino)-phenyleddikesyre, fremgangsmåde til fremstilling af disse salte og saltenes anvendelse som topisk anvendelse farmaceutiske præparater |
FR2708611B1 (fr) * | 1993-07-29 | 1995-10-27 | Meram Lab | Sel de codéine de l'acide 2-(3-benzoylphényl)propionique, procédé d'obtention et compositions pharmaceutiques le contenant. |
DE19607395C2 (de) * | 1996-02-28 | 2002-11-21 | Lohmann Therapie Syst Lts | Salze aus einem kationischen narkotischen Analgetikum mit einem anionischen nichtnarkotischen Analgetikum, Verfahren zu deren Herstellung und die diese Salze enthaltenden pharmazeutischen Präparate |
RS49982B (sr) * | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
EP1017696B1 (de) * | 1997-09-25 | 2002-03-20 | LTS Lohmann Therapie-Systeme AG | Säureadditionssalze von morphin-alkaloiden und deren verwendung |
CN1514729B (zh) * | 2001-06-05 | 2012-09-05 | 控制释放系统公司 | 缓释的止痛化合物 |
AU2002350207A1 (en) * | 2001-11-19 | 2003-06-10 | Control Delivery Systems, Inc. | Topical delivery of codrugs |
US10004729B2 (en) | 2002-07-05 | 2018-06-26 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
US8840928B2 (en) * | 2002-07-05 | 2014-09-23 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
US8557291B2 (en) | 2002-07-05 | 2013-10-15 | Collegium Pharmaceutical, Inc. | Abuse-deterrent pharmaceutical compositions of opioids and other drugs |
WO2004004693A1 (en) * | 2002-07-05 | 2004-01-15 | Collgegium Pharmaceutical | Abuse-deterrent pharmaceutical compositions of opiods and other drugs |
TW200500067A (en) * | 2003-01-21 | 2005-01-01 | Control Delivery Sys Inc | Salts of codrugs and uses related thereto |
ES2653568T3 (es) * | 2004-06-12 | 2018-02-07 | Collegium Pharmaceutical, Inc. | Formulaciones de fármacos para la prevención del abuso |
US20090291121A1 (en) * | 2008-05-23 | 2009-11-26 | Symrise, Inc. | Capsule and coated capsules as a delivery system for dietary supplements and therapeutic materials |
BRPI1006222A2 (pt) | 2009-03-12 | 2016-08-02 | Cumberland Pharmaceuticas Inc | uso de ibuprofeno na redução de dor em pacientes humanos que são submetidos a cirurgia, uso de ibuprofeno na redução de dor cirúrgica em pacientes humanos e uso de ibuprofeno para melhorar o tempo ambulatorial após a operação em pacientes humanos que sorem procedimentos cirúrgicos ortopédicos |
US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
US10765634B2 (en) | 2012-01-24 | 2020-09-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Controlled release formulations for the induction and proliferation of blood cells |
US9072710B2 (en) | 2012-03-16 | 2015-07-07 | Cumberland Pharmaceuticals Inc. | Injectable ibuprofen formulation |
WO2017222575A1 (en) | 2016-06-23 | 2017-12-28 | Collegium Pharmaceutical, Inc. | Process of making more stable abuse-deterrent oral formulations |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA537946A (en) * | 1957-03-12 | J. Lewenstein Mozes | Process for preparing improved compounds having narcotic effect | |
US936254A (en) * | 1908-01-06 | 1909-10-05 | Belden Mfg Co | Attachment for telephones. |
DE377588C (de) * | 1922-08-29 | 1923-06-22 | O Hinsberg Dr | Verfahren zur Darstellung einer salzartigen Verbindung des Codeins |
US2628185A (en) * | 1949-04-01 | 1953-02-10 | Lewenstein Mozes Juda | Analgesic compounds and compositions |
US3895063A (en) * | 1965-04-08 | 1975-07-15 | Ciba Geigy Corp | Substituted Anilino Benzyl Alcohols |
FR2051482B1 (ru) * | 1969-04-04 | 1973-06-08 | Rabot Ets David | |
CA964192A (en) * | 1970-07-21 | 1975-03-11 | Roy H. Reiner | Long-acting narcotic antagonist formulations containing pamoate salts of dihydronormorphinone |
FR2257606B1 (ru) * | 1974-01-10 | 1978-02-24 | Sumitomo Chemical Co | |
US4176186A (en) * | 1978-07-28 | 1979-11-27 | Boehringer Ingelheim Gmbh | Quaternary derivatives of noroxymorphone which relieve intestinal immobility |
DE2935776A1 (de) * | 1979-09-05 | 1981-04-16 | Theodor Prof. Dr. 4400 Münster Eckert | Organische salze des indometacin, des naproxen und des diclofenac, ihre herstellung und sie enthaltende arzneimittel |
AT370721B (de) * | 1981-02-24 | 1983-04-25 | Ciba Geigy Ag | Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der |
CH664085A5 (de) * | 1985-02-08 | 1988-02-15 | Ciba Geigy Ag | Pharmazeutische praeparate mit analgetischer wirksamkeit, sowie deren herstellung. |
-
1991
- 1991-07-31 TW TW080105991A patent/TW225536B/zh active
- 1991-08-14 ES ES91810645T patent/ES2086515T3/es not_active Expired - Lifetime
- 1991-08-14 DE DE59107784T patent/DE59107784D1/de not_active Expired - Fee Related
- 1991-08-14 EP EP91810645A patent/EP0472501B1/de not_active Expired - Lifetime
- 1991-08-14 AT AT91810645T patent/ATE137753T1/de not_active IP Right Cessation
- 1991-08-14 DK DK91810645.1T patent/DK0472501T3/da active
- 1991-08-16 IL IL9921391A patent/IL99213A/en unknown
- 1991-08-16 US US07/746,676 patent/US5190947A/en not_active Expired - Fee Related
- 1991-08-21 CA CA002049649A patent/CA2049649A1/en not_active Abandoned
- 1991-08-21 PT PT98731A patent/PT98731B/pt not_active IP Right Cessation
- 1991-08-21 NZ NZ239495A patent/NZ239495A/en unknown
- 1991-08-21 AU AU82685/91A patent/AU652951B2/en not_active Ceased
- 1991-08-21 FI FI913949A patent/FI96421C/fi not_active IP Right Cessation
- 1991-08-22 ZA ZA916642A patent/ZA916642B/xx unknown
- 1991-08-22 HU HU912768A patent/HU209308B/hu not_active IP Right Cessation
- 1991-08-22 IE IE297391A patent/IE72479B1/en not_active IP Right Cessation
- 1991-08-22 KR KR1019910014490A patent/KR920004391A/ko active IP Right Grant
- 1991-08-22 JP JP3210723A patent/JPH04257587A/ja active Pending
- 1991-08-22 NO NO913295A patent/NO179175C/no unknown
-
1996
- 1996-05-09 GR GR960401132T patent/GR3019872T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO913295L (no) | 1992-02-24 |
FI96421C (fi) | 1996-06-25 |
PT98731A (pt) | 1992-07-31 |
NO179175C (no) | 1996-08-21 |
JPH04257587A (ja) | 1992-09-11 |
FI913949A0 (fi) | 1991-08-21 |
NO913295D0 (no) | 1991-08-22 |
ZA916642B (en) | 1992-04-29 |
ES2086515T3 (es) | 1996-07-01 |
EP0472501A2 (de) | 1992-02-26 |
ATE137753T1 (de) | 1996-05-15 |
GR3019872T3 (en) | 1996-08-31 |
HUT60501A (en) | 1992-09-28 |
IE72479B1 (en) | 1997-04-23 |
HU209308B (en) | 1994-04-28 |
EP0472501A3 (en) | 1993-02-24 |
EP0472501B1 (de) | 1996-05-08 |
HU912768D0 (en) | 1992-01-28 |
IE912973A1 (en) | 1992-02-26 |
CA2049649A1 (en) | 1992-02-24 |
AU652951B2 (en) | 1994-09-15 |
IL99213A (en) | 1995-07-31 |
NZ239495A (en) | 1997-05-26 |
KR920004391A (ko) | 1992-03-27 |
AU8268591A (en) | 1992-02-27 |
FI96421B (fi) | 1996-03-15 |
TW225536B (ru) | 1994-06-21 |
DE59107784D1 (de) | 1996-06-13 |
IL99213A0 (en) | 1992-07-15 |
US5190947A (en) | 1993-03-02 |
PT98731B (pt) | 1999-01-29 |
FI913949A (fi) | 1992-02-24 |
NO179175B (no) | 1996-05-13 |
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