PT88074A - Processo para a preparacao de antagonistas de leucotrieno e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de antagonistas de leucotrieno e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT88074A PT88074A PT88074A PT8807488A PT88074A PT 88074 A PT88074 A PT 88074A PT 88074 A PT88074 A PT 88074A PT 8807488 A PT8807488 A PT 8807488A PT 88074 A PT88074 A PT 88074A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- compounds
- leucotriene antagonists
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000005557 antagonist Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002243 precursor Substances 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003199 leukotriene receptor blocking agent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873724735 DE3724735A1 (de) | 1987-07-25 | 1987-07-25 | Leukotrienantagonisten, verfahren zu ihrer herstellung, ihre anwendung zur behandlung von krankheiten, sowie vorprodukte |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT88074A true PT88074A (pt) | 1989-06-30 |
| PT88074B PT88074B (pt) | 1995-03-01 |
Family
ID=6332390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT88074A PT88074B (pt) | 1987-07-25 | 1988-07-22 | Processo para a preparacao de antagonistas de leucotrieno e de composicoes farmaceuticas que os contem |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4851440A (pt) |
| EP (1) | EP0301401B1 (pt) |
| JP (1) | JPS6447759A (pt) |
| KR (1) | KR890001974A (pt) |
| AT (1) | ATE69809T1 (pt) |
| AU (1) | AU610201B2 (pt) |
| DE (2) | DE3724735A1 (pt) |
| DK (1) | DK412388A (pt) |
| ES (1) | ES2040783T3 (pt) |
| FI (1) | FI883455A (pt) |
| GR (1) | GR3003525T3 (pt) |
| IL (1) | IL87197A0 (pt) |
| NO (1) | NO167799C (pt) |
| NZ (1) | NZ225518A (pt) |
| PT (1) | PT88074B (pt) |
| ZA (1) | ZA885335B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5286895A (en) * | 1992-02-19 | 1994-02-15 | Merck & Co., Inc. | Cholesterol lowering compounds |
| KR100411191B1 (ko) * | 1996-06-12 | 2004-03-30 | 한솔제지주식회사 | 재활용이 용이한 방습지 |
| US20140107373A1 (en) * | 2011-05-19 | 2014-04-17 | Tokyo Instutute of Technology | Polyvalent Vinyl Aromatic Compound and Method for Producing Same |
| US12037327B2 (en) * | 2018-05-04 | 2024-07-16 | Saint Louis University | Compounds and methods targeting GPER for treatment of diseases associated with calcium |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3894080A (en) * | 1970-05-05 | 1975-07-08 | Rorer Inc William H | Phenylacetic acids |
| US3867434A (en) * | 1971-11-04 | 1975-02-18 | Rorer Inc William H | Phenyl butyric acids and derivatives thereof |
| AT336589B (de) * | 1974-05-20 | 1977-05-10 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen biphenylderivaten |
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| US4785004A (en) * | 1985-12-23 | 1988-11-15 | Ciba-Geigy Corporation | Aromatic thioethers |
| GB2190377A (en) * | 1986-05-14 | 1987-11-18 | Merck Frosst Canada Inc | Phenyldithiaalkanedioic acids as leukotriene antagonists |
-
1987
- 1987-07-25 DE DE19873724735 patent/DE3724735A1/de not_active Withdrawn
-
1988
- 1988-07-21 AT AT88111746T patent/ATE69809T1/de not_active IP Right Cessation
- 1988-07-21 ES ES198888111746T patent/ES2040783T3/es not_active Expired - Lifetime
- 1988-07-21 EP EP88111746A patent/EP0301401B1/de not_active Expired - Lifetime
- 1988-07-21 DE DE8888111746T patent/DE3866460D1/de not_active Expired - Fee Related
- 1988-07-21 FI FI883455A patent/FI883455A/fi not_active Application Discontinuation
- 1988-07-22 AU AU19296/88A patent/AU610201B2/en not_active Ceased
- 1988-07-22 DK DK412388A patent/DK412388A/da not_active Application Discontinuation
- 1988-07-22 JP JP63181945A patent/JPS6447759A/ja active Pending
- 1988-07-22 NO NO883286A patent/NO167799C/no unknown
- 1988-07-22 IL IL87197A patent/IL87197A0/xx unknown
- 1988-07-22 US US07/222,975 patent/US4851440A/en not_active Expired - Fee Related
- 1988-07-22 NZ NZ225518A patent/NZ225518A/xx unknown
- 1988-07-22 PT PT88074A patent/PT88074B/pt not_active IP Right Cessation
- 1988-07-22 ZA ZA885335A patent/ZA885335B/xx unknown
- 1988-07-23 KR KR1019880009266A patent/KR890001974A/ko not_active Application Discontinuation
-
1992
- 1992-01-08 GR GR910402037T patent/GR3003525T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2040783T3 (es) | 1993-11-01 |
| DE3724735A1 (de) | 1989-02-02 |
| US4851440A (en) | 1989-07-25 |
| FI883455A (fi) | 1989-01-26 |
| DK412388D0 (da) | 1988-07-22 |
| EP0301401A2 (de) | 1989-02-01 |
| ZA885335B (en) | 1989-03-29 |
| ATE69809T1 (de) | 1991-12-15 |
| JPS6447759A (en) | 1989-02-22 |
| IL87197A0 (en) | 1988-12-30 |
| KR890001974A (ko) | 1989-04-07 |
| DE3866460D1 (de) | 1992-01-09 |
| NO167799C (no) | 1991-12-11 |
| EP0301401B1 (de) | 1991-11-27 |
| NZ225518A (en) | 1990-08-28 |
| DK412388A (da) | 1989-01-26 |
| AU610201B2 (en) | 1991-05-16 |
| NO883286D0 (no) | 1988-07-22 |
| EP0301401A3 (en) | 1989-05-10 |
| NO167799B (no) | 1991-09-02 |
| NO883286L (no) | 1989-01-26 |
| PT88074B (pt) | 1995-03-01 |
| AU1929688A (en) | 1989-01-27 |
| FI883455A0 (fi) | 1988-07-21 |
| GR3003525T3 (pt) | 1993-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940808 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960229 |