DK0426395T3 - - Google Patents

Info

Publication number
DK0426395T3
DK0426395T3 DK90311771.1T DK90311771T DK0426395T3 DK 0426395 T3 DK0426395 T3 DK 0426395T3 DK 90311771 T DK90311771 T DK 90311771T DK 0426395 T3 DK0426395 T3 DK 0426395T3
Authority
DK
Denmark
Prior art keywords
assay procedure
range
endotoxin
substantial improvement
previously available
Prior art date
Application number
DK90311771.1T
Other languages
Danish (da)
English (en)
Inventor
Ronald N Berzofsky
Original Assignee
Biowhittaker Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23698313&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0426395(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biowhittaker Inc filed Critical Biowhittaker Inc
Application granted granted Critical
Publication of DK0426395T3 publication Critical patent/DK0426395T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK90311771.1T 1989-10-30 1990-10-26 DK0426395T3 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42830089A 1989-10-30 1989-10-30

Publications (1)

Publication Number Publication Date
DK0426395T3 true DK0426395T3 (enExample) 1997-03-03

Family

ID=23698313

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90311771.1T DK0426395T3 (enExample) 1989-10-30 1990-10-26

Country Status (10)

Country Link
US (1) US5310657A (enExample)
EP (1) EP0426395B1 (enExample)
JP (1) JP2955345B2 (enExample)
AT (1) ATE148230T1 (enExample)
AU (1) AU644109B2 (enExample)
CA (1) CA2028789C (enExample)
DE (1) DE69029785T2 (enExample)
DK (1) DK0426395T3 (enExample)
ES (1) ES2098256T3 (enExample)
GR (1) GR3023298T3 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0549102B1 (en) * 1991-12-25 1996-07-03 Maruha Corporation Beta-glucans detection reagents and methods of detecting beta-glucans
JP3242733B2 (ja) * 1993-02-26 2001-12-25 生化学工業株式会社 エンドトキシン特異的測定剤
US6270982B1 (en) 1997-10-09 2001-08-07 Charles River Laboratories Methods and compositions for the detection of bacterial endotoxins
JP4235279B2 (ja) * 1998-04-10 2009-03-11 生化学工業株式会社 新規酵素反応測定法
US20050244299A1 (en) * 2002-04-30 2005-11-03 Biowittaker Technologies Inc Automated sequential injection analysis systems for the determination of trace endotoxin levels
US20040138577A1 (en) * 2002-12-20 2004-07-15 Kline Jeffrey A. Disposable hand-held device for collection of exhaled breath condensate
US7828741B2 (en) * 2002-12-20 2010-11-09 The Charlotte-Mecklenburg Hospital Authority Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
WO2004073497A2 (en) * 2003-02-14 2004-09-02 The Charlotte-Mecklenburg Hospital Authority Device and method for collection of exhaled alveolar breath condensate
US7329538B2 (en) 2003-03-17 2008-02-12 Charles River Laboratories, Inc. Methods and compositions for the detection of microbial contaminants
US20050026239A1 (en) * 2003-04-18 2005-02-03 Associates Of Cape Cod, Inc. Kit for detecting endotoxin in aqueous solutions
US20050048655A1 (en) * 2003-04-18 2005-03-03 Novitsky Thomas J. Kit for detecting endotoxin
CA2517890A1 (en) * 2003-11-07 2005-05-26 Cambrex Bio Science Walkersville, Inc. On-line apparatus and method for determining endotoxin levels
US7968280B2 (en) * 2004-12-02 2011-06-28 Charles River Laboratories, Inc. Methods for the detection and/or quantification of gram positive bacterial contaminants
DE602006004553D1 (de) 2005-01-13 2009-02-12 Charles River Lab Inc Verfahren zur klassifizierung von mikroben in einer biologischen probe
CN101454448A (zh) * 2006-07-07 2009-06-10 生化学工业株式会社 凝固酶原以及使用所述酶检测内毒素或(1→3)-β-D-葡聚糖的方法
US20080124248A1 (en) * 2006-11-29 2008-05-29 Edward Andrew Sobek Endotoxins and glucans quantification in indoor air
WO2009137244A1 (en) * 2008-04-15 2009-11-12 Charles River Laboratories, Inc. Cartridge and method for sample analysis
CA2755276A1 (en) 2009-03-13 2010-09-16 Kowa Company, Ltd. Method for measuring physiologically active substance of biological origin, program for implementing the same, and apparatus for measuring physiologically active substance of biological origin
JP5489680B2 (ja) * 2009-12-02 2014-05-14 興和株式会社 生物由来の生理活性物質の測定方法、それを実行するためのプログラム及び、生物由来の生理活性物質の測定装置
EP2446018B1 (en) 2009-06-26 2017-01-18 Charles River Laboratories, Inc. Heat-treated limulus amebocyte lysates
GB2477752A (en) * 2010-02-11 2011-08-17 Arab Biotechnology Company Detection of bacteria
CU24073B1 (es) 2011-12-27 2015-01-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
US20130078665A1 (en) * 2012-07-18 2013-03-28 Deepika Bodapati Test strip, a test kit and a method for detection of endotoxin in food
EP3425401B1 (en) 2012-10-08 2023-09-27 BL Technologies, Inc. Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making
US10309947B2 (en) 2013-02-27 2019-06-04 Trace-Ability, Inc. System and method for radiosynthesis, quality control and dose dispensing
US10895563B2 (en) 2014-02-26 2021-01-19 Trace-Ability, Inc. Palette-based systems for analyte characterization
US11002717B2 (en) 2014-02-26 2021-05-11 Trace-Ability, Inc. Systems and methods for characterizing radioactive analytes
IL264464B2 (en) * 2016-08-03 2024-02-01 Lonza Walkersville Inc A method for detecting endotoxin using Limulus extract of amoeba, which is mainly free of coagulogen
WO2018132562A1 (en) 2017-01-11 2018-07-19 Lonza Walkersville, Inc. Coagulogen-free clarified limulus amebocyte lysate
EP3622297A1 (en) 2017-06-28 2020-03-18 Lonza Walkersville, Inc. Cartridge for endotoxin detection
US11892397B2 (en) * 2017-10-17 2024-02-06 Board Of Regents, The University Of Texas System Endotoxin testing assay and method of same
CN109387637A (zh) * 2018-10-12 2019-02-26 四川升和药业股份有限公司 丹参注射液细菌内毒素检测方法
CN111077307B (zh) * 2018-10-21 2022-08-23 厦门鲎试剂生物科技股份有限公司 一种用革兰氏阴性细菌感染快速检测脓毒病的新方法
US12158471B2 (en) 2022-02-11 2024-12-03 Charles River Laboratories, Inc. Recombinant amebocyte lysate and uses thereof
CN121443750A (zh) 2023-06-05 2026-01-30 查尔斯河实验室公司 重组变形细胞凝血因子及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5415797A (en) * 1977-06-14 1979-02-05 Seikagaku Kogyo Co Ltd Detection and measurement of toxin in cells
US4322217A (en) * 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
US4406832A (en) * 1981-09-03 1983-09-27 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
US4510241A (en) * 1981-09-03 1985-04-09 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
DE3439761A1 (de) * 1984-10-31 1986-05-07 Klaus-Peter 6800 Mannheim Becker Verfahren zur bestimmung von endotoxinkonzentrationen

Also Published As

Publication number Publication date
CA2028789C (en) 2001-02-06
EP0426395B1 (en) 1997-01-22
CA2028789A1 (en) 1991-05-01
ATE148230T1 (de) 1997-02-15
DE69029785D1 (de) 1997-03-06
DE69029785T2 (de) 1997-05-28
US5310657A (en) 1994-05-10
AU644109B2 (en) 1993-12-02
JP2955345B2 (ja) 1999-10-04
AU6555690A (en) 1991-05-02
ES2098256T3 (es) 1997-05-01
EP0426395A1 (en) 1991-05-08
JPH03220456A (ja) 1991-09-27
GR3023298T3 (en) 1997-07-30

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