DK0401981T3 - Pyridazinonderivater - Google Patents
PyridazinonderivaterInfo
- Publication number
- DK0401981T3 DK0401981T3 DK90305015.1T DK90305015T DK0401981T3 DK 0401981 T3 DK0401981 T3 DK 0401981T3 DK 90305015 T DK90305015 T DK 90305015T DK 0401981 T3 DK0401981 T3 DK 0401981T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- pyrido
- pyridazine
- oxo
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/350,417 US4996204A (en) | 1989-05-11 | 1989-05-11 | Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0401981T3 true DK0401981T3 (da) | 1995-09-04 |
Family
ID=23376622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90305015.1T DK0401981T3 (da) | 1989-05-11 | 1990-05-10 | Pyridazinonderivater |
Country Status (18)
Country | Link |
---|---|
US (1) | US4996204A (de) |
EP (1) | EP0401981B1 (de) |
JP (1) | JPH0631235B2 (de) |
KR (1) | KR920003559B1 (de) |
AT (1) | ATE121743T1 (de) |
AU (1) | AU611610B2 (de) |
CA (1) | CA2016326C (de) |
DE (1) | DE69018876T2 (de) |
DK (1) | DK0401981T3 (de) |
ES (1) | ES2071016T3 (de) |
FI (1) | FI93013C (de) |
HU (1) | HU206714B (de) |
IE (1) | IE66029B1 (de) |
IL (1) | IL94302A (de) |
NO (1) | NO173938C (de) |
NZ (1) | NZ233599A (de) |
PT (1) | PT93984B (de) |
ZA (1) | ZA903564B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4954629A (en) * | 1989-05-11 | 1990-09-04 | Pfizer Inc. | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof |
US5716954A (en) * | 1991-10-09 | 1998-02-10 | Syntex U.S.A. Inc. | Benzopyridazinone and pyridopyridazinone compounds |
NZ254550A (en) * | 1992-09-28 | 1997-08-22 | Pfizer | Use of nitrogen-substituted pyrimidines to prepare medicaments useful for treatment or prevention of diabetic complications |
GB9314412D0 (en) * | 1993-07-13 | 1993-08-25 | Rhone Poulenc Agriculture | New compositions of matter |
BR9909358A (pt) | 1998-03-31 | 2000-12-12 | Inst For Pharm Discovery Inc | Composto, composição farmacêutica, e, processo para prevenção ou alìvio de complicações crÈnicas decorrentes de diabetes melito |
TNSN99224A1 (fr) | 1998-12-01 | 2005-11-10 | Inst For Pharm Discovery Inc | Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique |
IL155710A0 (en) * | 2000-11-30 | 2003-11-23 | Pfizer Prod Inc | Combination of gaba agonists and aldose reductase inhibitors |
DE60204611T2 (de) | 2001-02-28 | 2006-05-11 | Pfizer Products Inc., Groton | Sulfonyl-pyridazinon-derivate zur Verwendung als Aldose-reduktase-inhibitoren |
ATE286049T1 (de) | 2001-03-30 | 2005-01-15 | Pfizer Prod Inc | Pyridazinonaldose reductase inhibitoren |
EP1392310A1 (de) * | 2001-04-30 | 2004-03-03 | Pfizer Products Inc. | Kombinationen von aldose-reduktase-inhibitoren und cyclooxygenase-2-inhibitoren |
AU761191B2 (en) | 2001-05-24 | 2003-05-29 | Pfizer Products Inc. | Therapies for tissue damage resulting from ischemia |
US7572910B2 (en) * | 2003-02-20 | 2009-08-11 | Pfizer, Inc. | Pyridazinone aldose reductase inhibitors |
US8916563B2 (en) | 2010-07-16 | 2014-12-23 | The Trustees Of Columbia University In The City Of New York | Aldose reductase inhibitors and uses thereof |
JP5934206B2 (ja) * | 2010-07-16 | 2016-06-15 | ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | アルドース還元酵素阻害剤および同使用方法 |
IL304979A (en) | 2016-06-21 | 2023-10-01 | Univ Columbia | Aldose reductase inhibitors and methods of using them |
PT3658142T (pt) | 2017-07-28 | 2024-06-27 | Applied Therapeutics Inc | Composições e métodos para tratar galactosemia |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
DE2708187A1 (de) * | 1977-02-25 | 1978-08-31 | Thomae Gmbh Dr K | Neue pyrido-pyridazin-one |
IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
US4209527A (en) * | 1979-05-16 | 1980-06-24 | Pfizer Inc. | Benzimidazolone derivatives |
CA1160518A (en) * | 1979-07-06 | 1984-01-17 | E. I. Du Pont De Nemours And Company | Coated cookware with fep topcoat |
EP0222576B1 (de) * | 1985-11-07 | 1992-03-18 | Pfizer Inc. | Heterocyclische Oxophthalazinylessigsäure |
US4954629A (en) * | 1989-05-11 | 1990-09-04 | Pfizer Inc. | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof |
-
1989
- 1989-05-11 US US07/350,417 patent/US4996204A/en not_active Expired - Lifetime
-
1990
- 1990-05-06 IL IL9430290A patent/IL94302A/en not_active IP Right Cessation
- 1990-05-08 NZ NZ233599A patent/NZ233599A/en unknown
- 1990-05-09 PT PT93984A patent/PT93984B/pt not_active IP Right Cessation
- 1990-05-09 CA CA002016326A patent/CA2016326C/en not_active Expired - Fee Related
- 1990-05-10 DE DE69018876T patent/DE69018876T2/de not_active Expired - Fee Related
- 1990-05-10 EP EP90305015A patent/EP0401981B1/de not_active Expired - Lifetime
- 1990-05-10 ES ES90305015T patent/ES2071016T3/es not_active Expired - Lifetime
- 1990-05-10 FI FI902335A patent/FI93013C/fi not_active IP Right Cessation
- 1990-05-10 ZA ZA903564A patent/ZA903564B/xx unknown
- 1990-05-10 NO NO902070A patent/NO173938C/no unknown
- 1990-05-10 AU AU54905/90A patent/AU611610B2/en not_active Ceased
- 1990-05-10 HU HU902996A patent/HU206714B/hu not_active IP Right Cessation
- 1990-05-10 AT AT90305015T patent/ATE121743T1/de not_active IP Right Cessation
- 1990-05-10 KR KR1019900006808A patent/KR920003559B1/ko not_active IP Right Cessation
- 1990-05-10 DK DK90305015.1T patent/DK0401981T3/da active
- 1990-05-11 IE IE170190A patent/IE66029B1/en unknown
- 1990-05-11 JP JP2122832A patent/JPH0631235B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO173938B (no) | 1993-11-15 |
JPH0631235B2 (ja) | 1994-04-27 |
ZA903564B (en) | 1992-08-26 |
ES2071016T3 (es) | 1995-06-16 |
JPH035481A (ja) | 1991-01-11 |
PT93984A (pt) | 1991-01-08 |
NZ233599A (en) | 1991-07-26 |
KR920003559B1 (ko) | 1992-05-04 |
AU5490590A (en) | 1990-11-15 |
ATE121743T1 (de) | 1995-05-15 |
IL94302A (en) | 1994-01-25 |
PT93984B (pt) | 1996-11-29 |
HU902996D0 (en) | 1990-09-28 |
EP0401981A1 (de) | 1990-12-12 |
NO173938C (no) | 1994-02-23 |
EP0401981B1 (de) | 1995-04-26 |
FI93013B (fi) | 1994-10-31 |
AU611610B2 (en) | 1991-06-13 |
HU206714B (en) | 1992-12-28 |
DE69018876T2 (de) | 1995-08-24 |
FI93013C (fi) | 1995-02-10 |
DE69018876D1 (de) | 1995-06-01 |
IE901701L (en) | 1990-11-11 |
CA2016326C (en) | 1995-05-30 |
HUT54683A (en) | 1991-03-28 |
FI902335A0 (fi) | 1990-05-10 |
CA2016326A1 (en) | 1990-11-11 |
KR900018092A (ko) | 1990-12-20 |
NO902070D0 (no) | 1990-05-10 |
IE66029B1 (en) | 1995-11-29 |
NO902070L (no) | 1990-11-12 |
IL94302A0 (en) | 1991-03-10 |
US4996204A (en) | 1991-02-26 |
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