DK0401747T3 - Anvendelse af rapamycin og derivater og prolægemidler deraf til fremstilling af et lægemiddel til hæmning af transplantatafstødning hos pattedyr - Google Patents

Anvendelse af rapamycin og derivater og prolægemidler deraf til fremstilling af et lægemiddel til hæmning af transplantatafstødning hos pattedyr

Info

Publication number
DK0401747T3
DK0401747T3 DK90110612T DK90110612T DK0401747T3 DK 0401747 T3 DK0401747 T3 DK 0401747T3 DK 90110612 T DK90110612 T DK 90110612T DK 90110612 T DK90110612 T DK 90110612T DK 0401747 T3 DK0401747 T3 DK 0401747T3
Authority
DK
Denmark
Prior art keywords
rapamycin
transplant rejection
inhibition
prodrugs
mammals
Prior art date
Application number
DK90110612T
Other languages
English (en)
Inventor
Roy Calne
Original Assignee
Roy Calne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23425763&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0401747(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roy Calne filed Critical Roy Calne
Application granted granted Critical
Publication of DK0401747T3 publication Critical patent/DK0401747T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DK90110612T 1989-06-06 1990-06-05 Anvendelse af rapamycin og derivater og prolægemidler deraf til fremstilling af et lægemiddel til hæmning af transplantatafstødning hos pattedyr DK0401747T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/362,354 US5100899A (en) 1989-06-06 1989-06-06 Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof

Publications (1)

Publication Number Publication Date
DK0401747T3 true DK0401747T3 (da) 2004-03-08

Family

ID=23425763

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90110612T DK0401747T3 (da) 1989-06-06 1990-06-05 Anvendelse af rapamycin og derivater og prolægemidler deraf til fremstilling af et lægemiddel til hæmning af transplantatafstødning hos pattedyr

Country Status (18)

Country Link
US (5) US5100899A (da)
EP (1) EP0401747B1 (da)
JP (1) JP2969150B2 (da)
KR (1) KR0160957B1 (da)
AT (1) ATE135215T1 (da)
AU (1) AU638253B2 (da)
CA (1) CA2018287C (da)
DE (2) DE69025803T2 (da)
DK (1) DK0401747T3 (da)
ES (1) ES2085299T3 (da)
GR (1) GR3019792T3 (da)
HK (1) HK1005704A1 (da)
HU (1) HU206974B (da)
IL (1) IL94634A (da)
LU (1) LU90831I2 (da)
MX (1) MX173183B (da)
NL (1) NL300056I2 (da)
SG (1) SG44632A1 (da)

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* Cited by examiner, † Cited by third party
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HUT54047A (en) 1991-01-28
DE69025803T2 (de) 1996-07-25
ES2085299T3 (es) 1996-06-01
LU90831I2 (fr) 2001-11-12
CA2018287A1 (en) 1990-12-06
MX173183B (es) 1994-02-07
GR3019792T3 (en) 1996-07-31
JP2969150B2 (ja) 1999-11-02
HU206974B (en) 1993-03-01
EP0401747A3 (en) 1991-07-03
HK1005704A1 (en) 1999-01-22
ATE135215T1 (de) 1996-03-15
US5461058A (en) 1995-10-24
JPH0373158A (ja) 1991-03-28
US5100899A (en) 1992-03-31
AU638253B2 (en) 1993-06-24
DE69025803D1 (de) 1996-04-18
AU5686590A (en) 1991-01-31
KR910000169A (ko) 1991-01-29
NL300056I1 (nl) 2001-12-01
SG44632A1 (en) 1997-12-19
US5403833A (en) 1995-04-04
US5308847A (en) 1994-05-03
DE10199045I2 (de) 2006-07-13
US5212155A (en) 1993-05-18
KR0160957B1 (ko) 1998-12-01
NL300056I2 (nl) 2002-04-02
IL94634A0 (en) 1991-04-15
CA2018287C (en) 2001-11-20
HU903487D0 (en) 1990-12-28
EP0401747B1 (en) 1996-03-13
EP0401747A2 (en) 1990-12-12
DE10199045I1 (de) 2003-06-05
IL94634A (en) 1996-03-31

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