DE9200270U1 - Reagenz zum sequentiellen Abbau von Proteinen und Peptiden nach Edman (Edman-Abbau) - Google Patents
Reagenz zum sequentiellen Abbau von Proteinen und Peptiden nach Edman (Edman-Abbau)Info
- Publication number
- DE9200270U1 DE9200270U1 DE9200270U DE9200270U DE9200270U1 DE 9200270 U1 DE9200270 U1 DE 9200270U1 DE 9200270 U DE9200270 U DE 9200270U DE 9200270 U DE9200270 U DE 9200270U DE 9200270 U1 DE9200270 U1 DE 9200270U1
- Authority
- DE
- Germany
- Prior art keywords
- edman
- degradation
- reagent
- proteins
- peptides according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000015556 catabolic process Effects 0.000 title claims description 13
- 239000003153 chemical reaction reagent Substances 0.000 title claims description 13
- 238000006731 degradation reaction Methods 0.000 title claims description 13
- 108090000765 processed proteins & peptides Proteins 0.000 title claims description 7
- 102000004169 proteins and genes Human genes 0.000 title claims description 7
- 108090000623 proteins and genes Proteins 0.000 title claims description 7
- 102000004196 processed proteins & peptides Human genes 0.000 title claims description 6
- 125000000217 alkyl group Chemical group 0.000 claims description 5
- 125000001424 substituent group Chemical group 0.000 claims description 3
- CFNMUZCFSDMZPQ-GHXNOFRVSA-N 7-[(z)-3-methyl-4-(4-methyl-5-oxo-2h-furan-2-yl)but-2-enoxy]chromen-2-one Chemical compound C=1C=C2C=CC(=O)OC2=CC=1OC/C=C(/C)CC1OC(=O)C(C)=C1 CFNMUZCFSDMZPQ-GHXNOFRVSA-N 0.000 claims 2
- 230000035945 sensitivity Effects 0.000 description 6
- 150000001413 amino acids Chemical class 0.000 description 4
- 150000001893 coumarin derivatives Chemical class 0.000 description 4
- QKFJKGMPGYROCL-UHFFFAOYSA-N phenyl isothiocyanate Chemical compound S=C=NC1=CC=CC=C1 QKFJKGMPGYROCL-UHFFFAOYSA-N 0.000 description 4
- 238000001514 detection method Methods 0.000 description 2
- 229940117953 phenylisothiocyanate Drugs 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- UJKWLAZYSLJTKA-UHFFFAOYSA-N edma Chemical compound O1CCOC2=CC(CC(C)NC)=CC=C21 UJKWLAZYSLJTKA-UHFFFAOYSA-N 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 150000002540 isothiocyanates Chemical class 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- -1 phenylthiohydantoin amino acid Chemical class 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000000825 ultraviolet detection Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9200270U DE9200270U1 (de) | 1992-01-11 | 1992-01-11 | Reagenz zum sequentiellen Abbau von Proteinen und Peptiden nach Edman (Edman-Abbau) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9200270U DE9200270U1 (de) | 1992-01-11 | 1992-01-11 | Reagenz zum sequentiellen Abbau von Proteinen und Peptiden nach Edman (Edman-Abbau) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE9200270U1 true DE9200270U1 (de) | 1992-03-19 |
Family
ID=6874943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE9200270U Expired - Lifetime DE9200270U1 (de) | 1992-01-11 | 1992-01-11 | Reagenz zum sequentiellen Abbau von Proteinen und Peptiden nach Edman (Edman-Abbau) |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE9200270U1 (da) |
-
1992
- 1992-01-11 DE DE9200270U patent/DE9200270U1/de not_active Expired - Lifetime
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