DE78191T1 - Kollagenhemmende zusammensetzungen - Google Patents

Kollagenhemmende zusammensetzungen

Info

Publication number
DE78191T1
DE78191T1 DE198282401887T DE82401887T DE78191T1 DE 78191 T1 DE78191 T1 DE 78191T1 DE 198282401887 T DE198282401887 T DE 198282401887T DE 82401887 T DE82401887 T DE 82401887T DE 78191 T1 DE78191 T1 DE 78191T1
Authority
DE
Germany
Prior art keywords
proline
cis
hydroxy
synthesis
picolinic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198282401887T
Other languages
German (de)
English (en)
Inventor
Darwin J. Princeton New Jersey 08540 Prockop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers Health
Original Assignee
University of Medicine and Dentistry of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Medicine and Dentistry of New Jersey filed Critical University of Medicine and Dentistry of New Jersey
Publication of DE78191T1 publication Critical patent/DE78191T1/de
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
DE198282401887T 1981-10-16 1982-10-14 Kollagenhemmende zusammensetzungen Pending DE78191T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/311,920 US4428939A (en) 1981-10-16 1981-10-16 Collagen inhibiting compositions and processes for manufacturing and using same

Publications (1)

Publication Number Publication Date
DE78191T1 true DE78191T1 (de) 1983-09-15

Family

ID=23209071

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198282401887T Pending DE78191T1 (de) 1981-10-16 1982-10-14 Kollagenhemmende zusammensetzungen
DE8282401887T Expired DE3273044D1 (en) 1981-10-16 1982-10-14 Collagen inhibiting compositions and processes for manufacturing and using the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8282401887T Expired DE3273044D1 (en) 1981-10-16 1982-10-14 Collagen inhibiting compositions and processes for manufacturing and using the same

Country Status (8)

Country Link
US (1) US4428939A (https=)
EP (1) EP0078191B1 (https=)
JP (1) JPS58140022A (https=)
AT (1) ATE21823T1 (https=)
CA (1) CA1239393A (https=)
DE (2) DE78191T1 (https=)
IL (1) IL67027A (https=)
ZA (1) ZA827359B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4625016A (en) * 1981-10-16 1986-11-25 University Of Medicine And Dentistry Of New Jersey Collagen inhibiting compositions and processes for manufacturing and using same
US20030186869A1 (en) * 1990-05-14 2003-10-02 George Poiani Polymer compositions comprising antifibrotic agents, and methods of treatment, pharmaceutical compositions, and methods of preparation therefor
US6517824B1 (en) 1990-05-14 2003-02-11 University Of Medicine & Denistry Of New Jersey Polymer compositions comprising antifibrotic agents, and methods of treatment, pharmaceutical compositions, and methods of preparation therefor
US5660822A (en) * 1990-05-14 1997-08-26 University Of Medicine & Dentistry Of N.J. Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use
US5372807A (en) * 1990-05-14 1994-12-13 University Of Medicine And Dentistry Of New Jersey Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
JPH05202177A (ja) * 1991-09-06 1993-08-10 Teijin Ltd 生分解性共重合体、及びそれを含有する医薬品組成物
JP2552155Y2 (ja) * 1992-01-07 1997-10-27 パロマ工業株式会社 水量調節装置
ATE218330T1 (de) * 1992-03-23 2002-06-15 Univ Manitoba Verwendung von transglutaminasehemmer zur behandlung des narbegewebes
WO1995019764A1 (en) * 1994-01-21 1995-07-27 Jonathan Javitt Cis-hydroxyproline analogs for eye treatment
DE10120456A1 (de) * 2001-04-26 2002-11-14 Degussa Polymergebundener Katalysator für die enantioselektive Aldol-/Mannichreaktion
US20080057491A1 (en) * 2003-02-07 2008-03-06 Mckee Patrick A Substrates and inhibitors of antiplasmin cleaving enzyme and methods of use
US8933201B2 (en) 2006-06-07 2015-01-13 The Board Of Regents Of The University Of Oklahoma Substrates and inhibitors of antiplasmin cleaving enzyme and fibroblast activation protein and methods of use
EP2566919B1 (en) * 2010-05-05 2016-05-11 Basell Poliolefine Italia S.r.l. Propylene polymer compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399887A (en) * 1971-06-10 1975-07-02 Prockop D J Composition and methods for controlling collagen synthesis
US3951939A (en) * 1972-01-08 1976-04-20 Behringwerke Aktiengesellschaft Polypeptides, process for their manufacture and their use as polyvalent isoinhibitors
US4265805A (en) * 1980-04-01 1981-05-05 American Cyanamid Company Polymeric light stabilizers containing tetralkyl piperidine moieties

Also Published As

Publication number Publication date
US4428939A (en) 1984-01-31
ZA827359B (en) 1983-08-31
EP0078191B1 (en) 1986-09-03
JPH0365325B2 (https=) 1991-10-11
JPS58140022A (ja) 1983-08-19
EP0078191A3 (en) 1983-08-17
DE3273044D1 (en) 1986-10-09
IL67027A0 (en) 1983-02-23
ATE21823T1 (de) 1986-09-15
EP0078191A2 (en) 1983-05-04
CA1239393A (en) 1988-07-19
IL67027A (en) 1986-11-30

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