GB1399887A - Composition and methods for controlling collagen synthesis - Google Patents

Composition and methods for controlling collagen synthesis

Info

Publication number
GB1399887A
GB1399887A GB2548472A GB2548472A GB1399887A GB 1399887 A GB1399887 A GB 1399887A GB 2548472 A GB2548472 A GB 2548472A GB 2548472 A GB2548472 A GB 2548472A GB 1399887 A GB1399887 A GB 1399887A
Authority
GB
United Kingdom
Prior art keywords
allo
proline
lysine
hydroxy
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2548472A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1399887A publication Critical patent/GB1399887A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

1399887 Controlling collagen synthesis D J PROCKOP 31 May 1972 [10 June 1971] 25484/72 Heading A5B Compositions for the control of the cellular synthesis of collagen in animals comprise an active ingredient selected from L-azetidine2-2 carboxylic acid, cis-4-hydroxy-L-proline, 3, 4- dehydro-L-proline, 2, 6-diamino-4-hexenoic acid, allo-5-fiuorohydroxy-L-lysine, allo-5- hydroxy-L-lysine and the laevo and cis isomers of compounds of the general structural formula Wherein R is OH, Cl, F, NH 2 , CH 3 , OC(O)CH 3 , OC(O)CN 2 CH 3 , SH, SOH3, OCH 3 , ONO 2 , OSO 3 H, H 2 PO 4 or COOH and a liquid or solid pharmaceutically acceptable carrier or diluent. The compositions may be administered orally, parenterally or locally in the form of tablets, powders, capsules, suspensions, solutions or emulsions.
GB2548472A 1971-06-10 1972-05-31 Composition and methods for controlling collagen synthesis Expired GB1399887A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15198671A 1971-06-10 1971-06-10

Publications (1)

Publication Number Publication Date
GB1399887A true GB1399887A (en) 1975-07-02

Family

ID=22541106

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2548472A Expired GB1399887A (en) 1971-06-10 1972-05-31 Composition and methods for controlling collagen synthesis

Country Status (4)

Country Link
BE (1) BE784650A (en)
DE (1) DE2228187A1 (en)
FR (1) FR2140598B1 (en)
GB (1) GB1399887A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2171302A (en) * 1984-11-05 1986-08-28 Dr Wilhelm Hoerrmann Therapeutic hydroxyprolines
WO1987004925A1 (en) * 1986-02-18 1987-08-27 Biota Scientific Management Pty. Ltd. Stimulation of angiogenesis
GB2226759A (en) * 1987-12-30 1990-07-11 Wilhelm Hoerrmann Pharmaceutical compositions containing lysine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428939A (en) * 1981-10-16 1984-01-31 Prockop Darwin J Collagen inhibiting compositions and processes for manufacturing and using same
GB8514075D0 (en) * 1985-06-04 1985-07-10 Shell Int Research Therapeutic compounds

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2171302A (en) * 1984-11-05 1986-08-28 Dr Wilhelm Hoerrmann Therapeutic hydroxyprolines
GB2171302B (en) * 1984-11-05 1989-08-23 Hoerrmann Wilhelm Tumour therapy
WO1987004925A1 (en) * 1986-02-18 1987-08-27 Biota Scientific Management Pty. Ltd. Stimulation of angiogenesis
GB2226759A (en) * 1987-12-30 1990-07-11 Wilhelm Hoerrmann Pharmaceutical compositions containing lysine

Also Published As

Publication number Publication date
BE784650A (en) 1972-12-11
FR2140598B1 (en) 1975-11-28
DE2228187A1 (en) 1972-12-14
FR2140598A1 (en) 1973-01-19

Similar Documents

Publication Publication Date Title
GB1351430A (en) Substituted 1,2,4-triazole derivatives
GB1422295A (en) Indole derivatives
GB1399887A (en) Composition and methods for controlling collagen synthesis
IL38972A (en) Substituted phenyl alkanol derivatives,their preparation and compositions containing them
GB1383088A (en) Pharmacologically active quinaldamide derivatives
GB1456627A (en) Pyridobenzodiazepinones
GB1446632A (en) 5-endo-benzoyloxy-n-amino-c2-4 alkyl- bicyclo-2,2,1-heptane - 2,3-d-endo-carboxylic acid imides
ES465537A1 (en) Novel benzylalcohol derivatives and processes for preparing the same
JPS5283380A (en) Synthesis of thiocarbostyril derivatives
GB1409648A (en) Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof
GB1187009A (en) Spiro-Imidazoline-Phthalan Derivatives and a Process for the Manufacture thereof
GB1398800A (en) Trisubstituted imidazoles
GB1473971A (en) 3-hydroxy-5,6-benzomorphinan derivatives
GB1354097A (en) Isoxazole derivatives
GB1318479A (en) N-bicycloamino-alkanoyl-anilines
GB1448295A (en) Thiosemicarbazones
JPS51115402A (en) Process for preparation of alpha-amino acid
GB1457950A (en) Antibacterial compositions
GB1512763A (en) 3-nitropyrazole-4-acrylic acid derivatives
GB1410787A (en) 3-arylsulphonyl-1,2,4-oxadiazoles
GB1147343A (en) Improvements in or relating to novel steroids and the manufacture thereof
GB1113262A (en) Improvements in or relating to substituted pyrazines and the manufacture thereof
GB1378073A (en) Hydrazines hydrazides and hydrazones of isoxazolopyridine carboxylic acids and esters
GB1394384A (en) Substituted xanthone carboxylic acid compounds
JPS5278881A (en) Synthesis of novel morpholine derivativs

Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees