DE69938065D1 - Methode zur Bestimmung des Stromflusses in einem Trennungskanal und Zusmmensetzung dafür - Google Patents

Methode zur Bestimmung des Stromflusses in einem Trennungskanal und Zusmmensetzung dafür

Info

Publication number
DE69938065D1
DE69938065D1 DE69938065T DE69938065T DE69938065D1 DE 69938065 D1 DE69938065 D1 DE 69938065D1 DE 69938065 T DE69938065 T DE 69938065T DE 69938065 T DE69938065 T DE 69938065T DE 69938065 D1 DE69938065 D1 DE 69938065D1
Authority
DE
Germany
Prior art keywords
polynucleotide
fluorescent
multiple color
separation apparatus
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69938065T
Other languages
English (en)
Other versions
DE69938065T2 (de
Inventor
Muhammed A Sharaf
Maria C Roque-Biewer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Publication of DE69938065D1 publication Critical patent/DE69938065D1/de
Application granted granted Critical
Publication of DE69938065T2 publication Critical patent/DE69938065T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DE69938065T 1998-09-16 1999-09-09 Methode zur Bestimmung des Stromflusses in einem Trennungskanal und Zusmmensetzung dafür Expired - Lifetime DE69938065T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/154,178 US6821402B1 (en) 1998-09-16 1998-09-16 Spectral calibration of fluorescent polynucleotide separation apparatus
US154178 2002-05-23

Publications (2)

Publication Number Publication Date
DE69938065D1 true DE69938065D1 (de) 2008-03-13
DE69938065T2 DE69938065T2 (de) 2009-01-22

Family

ID=22550319

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69931262T Expired - Lifetime DE69931262T2 (de) 1998-09-16 1999-09-09 Spektrale eichung von verschiedenen fluoreszierenden farbstoffen zur verwendung in einer vorrichtung zur trennung von fluoreszierenden polynucleotiden
DE69938065T Expired - Lifetime DE69938065T2 (de) 1998-09-16 1999-09-09 Methode zur Bestimmung des Stromflusses in einem Trennungskanal und Zusmmensetzung dafür

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69931262T Expired - Lifetime DE69931262T2 (de) 1998-09-16 1999-09-09 Spektrale eichung von verschiedenen fluoreszierenden farbstoffen zur verwendung in einer vorrichtung zur trennung von fluoreszierenden polynucleotiden

Country Status (8)

Country Link
US (5) US6821402B1 (de)
EP (2) EP1101104B1 (de)
JP (1) JP2002525576A (de)
AT (2) ATE326009T1 (de)
AU (1) AU748681B2 (de)
CA (1) CA2341740A1 (de)
DE (2) DE69931262T2 (de)
WO (1) WO2000016087A1 (de)

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SE9802558D0 (sv) 1998-07-16 1998-07-16 Hanning Instr Ab Device for detection of fluorescent
WO2001057495A2 (en) * 2000-02-01 2001-08-09 The Government Of The United States Of America As Represented By The Secretary, Department Of Health & Human Services Methods for predicting the biological, chemical, and physical properties of molecules from their spectral properties
US6734420B2 (en) 2000-04-06 2004-05-11 Quantum Dot Corporation Differentiable spectral bar code methods and systems
US20030170734A1 (en) * 2000-04-28 2003-09-11 Stephen Williams Multiplexed assays using electrophoretically separated molecular tags
JP2004505254A (ja) * 2000-07-21 2004-02-19 アプレラ　コーポレイション 測定データとスタンダードとの間のマッチングを評価するための方法およびシステム
US6863791B1 (en) * 2000-09-11 2005-03-08 Spectrumedix Llc Method for in-situ calibration of electrophoretic analysis systems
PL373962A1 (en) 2001-05-21 2005-09-19 Aclara Biosciences, Inc. Methods and compositions for analyzing proteins
EP1404878A4 (de) * 2001-07-11 2006-12-06 Applera Corp Interne kalibrierungsstandards für elektrophoretische analysen
US7220591B2 (en) 2001-12-04 2007-05-22 Cem Corporation Method and apparatus for rapid fat content determination
US6652273B2 (en) * 2002-01-14 2003-11-25 The Procter & Gamble Company Apparatus and method for controlling the temperature of manufacturing equipment
US20030203408A1 (en) * 2002-04-02 2003-10-30 Stephen Williams Computer-implemented method for identifying peaks in electropherogram data
US7331511B2 (en) 2002-12-23 2008-02-19 Agilent Technologies, Inc. Biopolymeric array scanners capable of automatic scale factor selection for a plurality of different dyes, and methods for making and using the same
US7444012B2 (en) 2003-07-24 2008-10-28 Freescale Semiconductor, Inc. Method and apparatus for performing failure analysis with fluorescence inks
US8084260B2 (en) * 2004-11-24 2011-12-27 Applied Biosystems, Llc Spectral calibration method and system for multiple instruments
JP4504207B2 (ja) * 2005-01-11 2010-07-14 オリンパス株式会社 蛍光剤集積濃度測定装置及び蛍光剤集積濃度測定方法
JP4742712B2 (ja) * 2005-07-14 2011-08-10 株式会社島津製作所 キャピラリー電気泳動方法
US8012327B2 (en) * 2006-01-16 2011-09-06 Hitachi High-Technologies Corporation Capillary electrophoresis apparatus and electrophoresis method
JP4679375B2 (ja) * 2006-01-25 2011-04-27 株式会社日立ハイテクノロジーズ キャピラリ電気泳動装置
US20080001099A1 (en) * 2006-07-01 2008-01-03 Sharaf Muhammad A Quantitative calibration method and system for genetic analysis instrumentation
US8005628B2 (en) * 2007-01-29 2011-08-23 Applied Biosystems, Llc Systems and methods for baseline correction using non-linear normalization
DE102007055386B4 (de) * 2007-11-20 2015-07-16 Boehringer Ingelheim Vetmedica Gmbh Verfahren zur Kalibrierung eines Sensorelements
EP2240613B1 (de) * 2008-02-06 2013-09-11 Ludwig-Maximilians-Universität München Thermooptische charakterisierung von nukleinsäuremolekülen
JP5937780B2 (ja) * 2010-11-11 2016-06-22 ソニー株式会社 蛍光スペクトル補正方法及び蛍光スペクトル測定装置
CN105143469B (zh) * 2013-05-24 2018-05-22 株式会社日立高新技术 核酸分析装置及使用其的核酸分析方法
GB201511508D0 (en) * 2015-07-01 2015-08-12 Ge Healthcare Bio Sciences Ab Method for determining a size of biomolecules
CN113736779B (zh) * 2021-09-26 2024-02-23 公安部第一研究所 一种八色荧光光谱校准试剂及其制备方法
CN114414542B (zh) * 2021-12-20 2024-01-12 成都瀚辰光翼科技有限责任公司 用于基因检测的荧光信号检测方法、装置、介质及设备
WO2023223547A1 (ja) * 2022-05-20 2023-11-23 株式会社日立ハイテク 電気泳動データ処理装置及び電気泳動データ処理方法

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US5821058A (en) * 1984-01-16 1998-10-13 California Institute Of Technology Automated DNA sequencing technique
US5171534A (en) * 1984-01-16 1992-12-15 California Institute Of Technology Automated DNA sequencing technique
US5138830A (en) 1989-07-04 1992-08-18 Hans Stahlecker Spinning machine having a plurality of drafting units
US5139630A (en) * 1991-05-31 1992-08-18 Beckman Instruments, Inc. Identification of sample constituents utilizing capillary electrophoresis
DE4214112A1 (de) * 1991-08-02 1993-02-04 Europ Lab Molekularbiolog Neues verfahren zur sequenzierung von nukleinsaeuren
US5365455A (en) * 1991-09-20 1994-11-15 Vanderbilt University Method and apparatus for automatic nucleic acid sequence determination
WO1993014224A1 (en) * 1992-01-14 1993-07-22 Applied Biosystems, Inc. Size-calibration dna fragment mixture and method
AU3816993A (en) * 1992-03-19 1993-10-21 Regents Of The University Of California, The Multiple tag labeling method for DNA sequencing
CA2159830C (en) 1994-04-29 2001-07-03 Timothy M Woudenberg System for real time detection of nucleic acid amplification products
US5853979A (en) * 1995-06-30 1998-12-29 Visible Genetics Inc. Method and system for DNA sequence determination and mutation detection with reference to a standard
US5556790A (en) * 1994-12-05 1996-09-17 Pettit; John W. Method for Automated DNA sequencing
JP3488531B2 (ja) * 1994-12-19 2004-01-19 コマツ電子金属株式会社 多結晶棒の吊り具
US6127134A (en) * 1995-04-20 2000-10-03 Carnegie Mellon University Difference gel electrophoresis using matched multiple dyes
US6017434A (en) * 1995-05-09 2000-01-25 Curagen Corporation Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments
US5582705A (en) 1995-05-19 1996-12-10 Iowa State University Research Foundation, Inc. Multiplexed capillary electrophoresis system
US5981186A (en) * 1995-06-30 1999-11-09 Visible Genetics, Inc. Method and apparatus for DNA-sequencing using reduced number of sequencing mixtures
JP3418292B2 (ja) * 1996-04-24 2003-06-16 株式会社日立製作所 遺伝子解析装置
US6015667A (en) 1996-06-03 2000-01-18 The Perkin-Emer Corporation Multicomponent analysis method including the determination of a statistical confidence interval
US5800690A (en) 1996-07-03 1998-09-01 Caliper Technologies Corporation Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces
US5871628A (en) * 1996-08-22 1999-02-16 The University Of Texas System Automatic sequencer/genotyper having extended spectral response

Also Published As

Publication number Publication date
CA2341740A1 (en) 2000-03-23
WO2000016087A1 (en) 2000-03-23
US20020125136A1 (en) 2002-09-12
US20040195101A1 (en) 2004-10-07
EP1178305A3 (de) 2004-01-14
JP2002525576A (ja) 2002-08-13
ATE384948T1 (de) 2008-02-15
EP1101104B1 (de) 2006-05-10
EP1178305A8 (de) 2002-05-22
US6821402B1 (en) 2004-11-23
DE69931262T2 (de) 2006-09-07
US20060102479A1 (en) 2006-05-18
AU748681B2 (en) 2002-06-13
EP1178305A2 (de) 2002-02-06
EP1101104A1 (de) 2001-05-23
AU5821099A (en) 2000-04-03
US20100096548A1 (en) 2010-04-22
DE69938065T2 (de) 2009-01-22
DE69931262D1 (de) 2006-06-14
ATE326009T1 (de) 2006-06-15
US6991712B2 (en) 2006-01-31
EP1178305B1 (de) 2008-01-23

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Legal Events

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Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

8380 Miscellaneous part iii

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8380 Miscellaneous part iii

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