ATE324466T1 - Methode zur analyse von oligonukleotidanaloga - Google Patents

Methode zur analyse von oligonukleotidanaloga

Info

Publication number
ATE324466T1
ATE324466T1 AT01966456T AT01966456T ATE324466T1 AT E324466 T1 ATE324466 T1 AT E324466T1 AT 01966456 T AT01966456 T AT 01966456T AT 01966456 T AT01966456 T AT 01966456T AT E324466 T1 ATE324466 T1 AT E324466T1
Authority
AT
Austria
Prior art keywords
oligonucleotide analogs
dna
analogs
complementary
charged
Prior art date
Application number
AT01966456T
Other languages
English (en)
Inventor
Dwight D Weller
Todime Muralimohan Reddy
Original Assignee
Avi Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avi Biopharma Inc filed Critical Avi Biopharma Inc
Application granted granted Critical
Publication of ATE324466T1 publication Critical patent/ATE324466T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01966456T 2000-08-30 2001-08-30 Methode zur analyse von oligonukleotidanaloga ATE324466T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22924500P 2000-08-30 2000-08-30

Publications (1)

Publication Number Publication Date
ATE324466T1 true ATE324466T1 (de) 2006-05-15

Family

ID=22860399

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01966456T ATE324466T1 (de) 2000-08-30 2001-08-30 Methode zur analyse von oligonukleotidanaloga

Country Status (10)

Country Link
US (1) US7264925B2 (de)
EP (1) EP1392853B1 (de)
JP (1) JP2004513625A (de)
KR (1) KR100916949B1 (de)
AT (1) ATE324466T1 (de)
AU (2) AU8696601A (de)
CA (1) CA2421043C (de)
DE (1) DE60119173T2 (de)
ES (1) ES2263651T3 (de)
WO (1) WO2002018656A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE498685T1 (de) 2004-06-28 2011-03-15 Univ Western Australia Antisense-oligonukleotide zur induktion von exon- skipping sowie verfahren zur verwendung davon
CN102203253B (zh) 2008-10-24 2016-04-06 萨雷普塔治疗公司 用于dmd的多外显子跳跃组合物
CN105838714B (zh) 2009-11-12 2020-07-17 西澳大利亚大学 反义分子和治疗疾病的方法
JP6061381B2 (ja) 2011-01-12 2017-01-18 積水メディカル株式会社 一塩基多型の検出方法
CN103314290B (zh) 2011-01-12 2015-07-01 积水医疗株式会社 核酸链的分离方法
WO2012133834A1 (ja) * 2011-03-31 2012-10-04 積水メディカル株式会社 一塩基多型検出用の試料核酸、一塩基多型検出試料調製用のｐｃｒプライマー及びイオン交換クロマトグラフィー分析に用いる一塩基多型検出用試料の調製方法
US9481905B2 (en) * 2013-02-19 2016-11-01 Orizhan Bioscience Limited Method of using neutrilized DNA (N-DNA) as surface probe for high throughput detection platform
BR122020016865B1 (pt) 2013-03-14 2022-12-27 Sarepta Therapeutics, Inc. Oligonucleotídeo antisenso, composição farmacêutica compreendendo o mesmo e uso da dita composição para o tratamento de distrofia muscular de duchenne (dmd)
CA2906812A1 (en) 2013-03-15 2014-09-18 Sarepta Therapeutics, Inc. Improved compositions for treating muscular dystrophy

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4279724A (en) * 1979-07-18 1981-07-21 Hearn Milton T W Preparative electrofocusing in flat bed granulated polysaccharide gels
US5405938A (en) * 1989-12-20 1995-04-11 Anti-Gene Development Group Sequence-specific binding polymers for duplex nucleic acids
US5034506A (en) * 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5932413A (en) * 1988-04-01 1999-08-03 Celebuski; Joseph Eugene DNA probe assay using neutrally charged probe strands
IL101356A (en) * 1991-04-03 1996-08-04 Perkin Elmer Corp Solvents for the separation of nucleic acids by replacing anions
US5641625A (en) * 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
AU2580892A (en) * 1991-09-05 1993-04-05 Isis Pharmaceuticals, Inc. Determination of oligonucleotides for therapeutics, diagnostics and research reagents
US6045995A (en) * 1994-08-24 2000-04-04 Isis Pharmaceuticals, Inc. Capillary electrophoretic detection of nucleic acids
JP2001502881A (ja) * 1995-05-18 2001-03-06 アボツト・ラボラトリーズ 高分子ペプチドプローブ及びその使用
WO1997012995A1 (en) * 1995-10-06 1997-04-10 Perseptive Biosystems, Inc. Methods and kit for hybridization analysis using peptide nucleic acid probes
US6613508B1 (en) * 1996-01-23 2003-09-02 Qiagen Genomics, Inc. Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
US5912332A (en) * 1996-07-26 1999-06-15 Hybridon, Inc. Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides
DK0975800T3 (da) * 1997-02-27 2003-09-22 Ingeneus Corp Analyse af nukleotider i opløsning under anvendelse af PNA-prober
US6046004A (en) * 1997-02-27 2000-04-04 Lorne Park Research, Inc. Solution hybridization of nucleic acids with antisense probes having modified backbones
WO1999023219A1 (en) * 1997-10-31 1999-05-14 Osiris Therapeutics, Inc. Human slit polypeptide and polynucleotides encoding same
US6263286B1 (en) * 1998-08-13 2001-07-17 U.S. Genomics, Inc. Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer
US6365351B1 (en) * 1999-01-29 2002-04-02 Avi Biopharma, Inc. Non-invasive method for detecting target RNA

Also Published As

Publication number Publication date
KR100916949B1 (ko) 2009-09-14
AU8696601A (en) 2002-03-13
KR20030040410A (ko) 2003-05-22
EP1392853A2 (de) 2004-03-03
WO2002018656A2 (en) 2002-03-07
WO2002018656A3 (en) 2003-12-24
AU2001286966B2 (en) 2007-03-01
JP2004513625A (ja) 2004-05-13
CA2421043C (en) 2012-07-31
DE60119173T2 (de) 2007-01-18
EP1392853B1 (de) 2006-04-26
DE60119173D1 (de) 2006-06-01
US20020110819A1 (en) 2002-08-15
US7264925B2 (en) 2007-09-04
CA2421043A1 (en) 2002-03-07
ES2263651T3 (es) 2006-12-16

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