DE69937546T2 - Mischmizell-arzneistoffverabreichungssystem und verfahren zu dessen herstellung - Google Patents
Mischmizell-arzneistoffverabreichungssystem und verfahren zu dessen herstellung Download PDFInfo
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- DE69937546T2 DE69937546T2 DE69937546T DE69937546T DE69937546T2 DE 69937546 T2 DE69937546 T2 DE 69937546T2 DE 69937546 T DE69937546 T DE 69937546T DE 69937546 T DE69937546 T DE 69937546T DE 69937546 T2 DE69937546 T2 DE 69937546T2
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 37
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- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 28
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Landscapes
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21114 | 1998-02-10 | ||
| US09/021,114 US6017545A (en) | 1998-02-10 | 1998-02-10 | Mixed micellar delivery system and method of preparation |
| US09/216,733 US6231882B1 (en) | 1998-02-10 | 1998-12-21 | Mixed micellar delivery system and method of preparation |
| US216733 | 1998-12-21 | ||
| PCT/CA1999/000106 WO1999040932A1 (en) | 1998-02-10 | 1999-02-05 | Mixed micellar pharmaceutical delivery system and method of preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69937546D1 DE69937546D1 (de) | 2007-12-27 |
| DE69937546T2 true DE69937546T2 (de) | 2008-05-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| DE69937546T Expired - Lifetime DE69937546T2 (de) | 1998-02-10 | 1999-02-05 | Mischmizell-arzneistoffverabreichungssystem und verfahren zu dessen herstellung |
Country Status (12)
| Country | Link |
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| US (2) | US6017545A (https=) |
| EP (1) | EP1053011B1 (https=) |
| JP (1) | JP4499282B2 (https=) |
| AT (1) | ATE378062T1 (https=) |
| AU (1) | AU750197B2 (https=) |
| BR (1) | BR9804295A (https=) |
| DE (1) | DE69937546T2 (https=) |
| DK (1) | DK1053011T3 (https=) |
| ES (1) | ES2296380T3 (https=) |
| NZ (1) | NZ506024A (https=) |
| PT (1) | PT1053011E (https=) |
| WO (1) | WO1999040932A1 (https=) |
Families Citing this family (81)
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| FR2686899B1 (fr) * | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| US6017545A (en) * | 1998-02-10 | 2000-01-25 | Modi; Pankaj | Mixed micellar delivery system and method of preparation |
| US6350458B1 (en) | 1998-02-10 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Mixed micellar drug deliver system and method of preparation |
| AU763251B2 (en) * | 1998-02-10 | 2003-07-17 | Generex Pharmaceuticals Inc. | Mixed micellar pharmaceutical delivery system and method for preparation |
| US6221378B1 (en) * | 1998-02-10 | 2001-04-24 | Generex Pharmaceuticals Incorporated | Mixed micellar delivery system and method of preparation |
| US7070799B1 (en) * | 1998-02-10 | 2006-07-04 | Generex Pharmaceuticals, Inc. | Method for administering insulin to the buccal region |
| US6193997B1 (en) * | 1998-09-27 | 2001-02-27 | Generex Pharmaceuticals Inc. | Proteinic drug delivery system using membrane mimetics |
| US6290987B1 (en) * | 1998-09-27 | 2001-09-18 | Generex Pharmaceuticals, Inc. | Mixed liposome pharmaceutical formulation with amphiphiles and phospholipids |
| US6635617B1 (en) * | 1998-10-16 | 2003-10-21 | Novo Nordisk A/S | Insulin preparations for pulmonary delivery containing menthol |
| EP1338272A1 (en) * | 1998-12-21 | 2003-08-27 | Generex Pharmaceuticals Inc. | Aerosol formulations for buccal and pulmonary application comprising chenodeoxycholate or deoxycholate |
| US6271200B1 (en) * | 1998-12-21 | 2001-08-07 | Generex Pharmaceuticals Inc. | Proteinic drug delivery system using aerosolized membrane-mimetic amphiphiles |
| US6375975B1 (en) * | 1998-12-21 | 2002-04-23 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary application |
| US7087215B2 (en) * | 1998-12-21 | 2006-08-08 | Generex Pharmaceuticals Incorporated | Methods of administering and enhancing absorption of pharmaceutical agents |
| US6451286B1 (en) * | 1998-12-21 | 2002-09-17 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds |
| US6312665B1 (en) * | 1998-12-21 | 2001-11-06 | Generex Pharmaceuticals Incorporated | Aerosol formulations for buccal and pulmonary application |
| AU2006200276B2 (en) * | 1998-12-21 | 2007-11-29 | Generex Pharmaceuticals Inc. | Micellar pharmaceutical compositions for buccal and pulmonary application |
| US6294153B1 (en) * | 1998-12-21 | 2001-09-25 | Generex Pharmaceuticals, Inc. | Aerosol pharmaceutical formulation for pulmonary and nasal delivery |
| US6436367B1 (en) * | 1998-12-21 | 2002-08-20 | Generex Pharmaceuticals Inc. | Aerosol formulations for buccal and pulmonary application |
| US6849263B2 (en) * | 1998-12-21 | 2005-02-01 | Generex Pharmaceutical Incorporated | Pharmaceutical compositions for buccal delivery of pain relief medications |
| US20040258763A1 (en) * | 1999-02-03 | 2004-12-23 | Bell Steve J.D. | Methods of manufacture and use of calcium phosphate particles containing allergens |
| CA2361421A1 (en) | 1999-02-03 | 2000-08-10 | Biosante Pharmaceuticals, Inc. | Therapeutic calcium phosphate particles and methods of manufacture and use |
| US20020054914A1 (en) * | 1999-02-03 | 2002-05-09 | Tulin Morcol | Compositions and methods for therapuetic agents complexed with calcium phosphate and encased by casein |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| NZ514319A (en) * | 1999-03-19 | 2002-11-26 | Generex Pharm Inc | Proteinic pharmaceutical agent solubilized in aerosol propellant in a pressurized container |
| US6350432B1 (en) * | 1999-03-19 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Pressurized container having an aerosolized pharmaceutical composition |
| RU2155602C1 (ru) | 1999-11-30 | 2000-09-10 | Оао "Куантум Сатис" | Инсулинсодержащее лекарственное средство для перорального применения и способ его получения |
| US6432383B1 (en) * | 2000-03-30 | 2002-08-13 | Generex Pharmaceuticals Incorporated | Method for administering insulin |
| WO2001072278A2 (en) * | 2000-03-30 | 2001-10-04 | Generex Pharmaceuticals Inc. | Method for administering insulin to the buccal region |
| EP2206720A1 (en) * | 2000-04-12 | 2010-07-14 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20050100991A1 (en) * | 2001-04-12 | 2005-05-12 | Human Genome Sciences, Inc. | Albumin fusion proteins |
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1998
- 1998-02-10 US US09/021,114 patent/US6017545A/en not_active Expired - Lifetime
- 1998-10-27 BR BR9804295-5A patent/BR9804295A/pt not_active IP Right Cessation
- 1998-12-21 US US09/216,733 patent/US6231882B1/en not_active Expired - Fee Related
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1999
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- 1999-02-05 AU AU25053/99A patent/AU750197B2/en not_active Revoked
- 1999-02-05 NZ NZ506024A patent/NZ506024A/en not_active IP Right Cessation
- 1999-02-05 DE DE69937546T patent/DE69937546T2/de not_active Expired - Lifetime
- 1999-02-05 EP EP99904638A patent/EP1053011B1/en not_active Expired - Lifetime
- 1999-02-05 ES ES99904638T patent/ES2296380T3/es not_active Expired - Lifetime
- 1999-02-05 AT AT99904638T patent/ATE378062T1/de active
- 1999-02-05 WO PCT/CA1999/000106 patent/WO1999040932A1/en not_active Ceased
- 1999-02-05 PT PT99904638T patent/PT1053011E/pt unknown
- 1999-02-05 DK DK99904638T patent/DK1053011T3/da active
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| DK1053011T3 (da) | 2008-03-25 |
| JP4499282B2 (ja) | 2010-07-07 |
| EP1053011A1 (en) | 2000-11-22 |
| AU2505399A (en) | 1999-08-30 |
| AU750197B2 (en) | 2002-07-11 |
| NZ506024A (en) | 2002-02-01 |
| US6017545A (en) | 2000-01-25 |
| EP1053011B1 (en) | 2007-11-14 |
| JP2003522096A (ja) | 2003-07-22 |
| PT1053011E (pt) | 2008-02-14 |
| ES2296380T3 (es) | 2008-04-16 |
| WO1999040932A1 (en) | 1999-08-19 |
| US6231882B1 (en) | 2001-05-15 |
| WO1999040932A9 (en) | 2000-03-30 |
| ATE378062T1 (de) | 2007-11-15 |
| DE69937546D1 (de) | 2007-12-27 |
| BR9804295A (pt) | 2000-03-28 |
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