DE69934366T2 - Transformierte mikroorganismen mit verbesserten eigenschaften - Google Patents

Transformierte mikroorganismen mit verbesserten eigenschaften Download PDF

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Publication number
DE69934366T2
DE69934366T2 DE69934366T DE69934366T DE69934366T2 DE 69934366 T2 DE69934366 T2 DE 69934366T2 DE 69934366 T DE69934366 T DE 69934366T DE 69934366 T DE69934366 T DE 69934366T DE 69934366 T2 DE69934366 T2 DE 69934366T2
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Prior art keywords
microorganism
strain
transformed
ethanol
xylose
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Expired - Lifetime
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DE69934366T
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German (de)
English (en)
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DE69934366D1 (de
Inventor
Aristos Maple Grove ARISTIDOU
John Londesborough
Merja Penttilä
Peter Richard
Laura Ruohonen
Hans SÖDERLUND
Anita Teleman
Mervi Toivari
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VTT Technical Research Centre of Finland Ltd
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VTT Technical Research Centre of Finland Ltd
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Publication of DE69934366T2 publication Critical patent/DE69934366T2/de
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • C12P7/625Polyesters of hydroxy carboxylic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Prevention Of Electric Corrosion (AREA)
DE69934366T 1998-03-11 1999-03-11 Transformierte mikroorganismen mit verbesserten eigenschaften Expired - Lifetime DE69934366T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI980551A FI980551A7 (fi) 1998-03-11 1998-03-11 Transformoidut mikro-organismit, joilla on parannettuja ominaisuuksia
FI980551 1998-03-11
PCT/FI1999/000185 WO1999046363A1 (en) 1998-03-11 1999-03-11 Transformed microorganisms with improved properties

Publications (2)

Publication Number Publication Date
DE69934366D1 DE69934366D1 (de) 2007-01-25
DE69934366T2 true DE69934366T2 (de) 2007-10-25

Family

ID=8551228

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69934366T Expired - Lifetime DE69934366T2 (de) 1998-03-11 1999-03-11 Transformierte mikroorganismen mit verbesserten eigenschaften

Country Status (13)

Country Link
US (1) US7091014B1 (https=)
EP (1) EP0981600B1 (https=)
JP (1) JP4573365B2 (https=)
AT (1) ATE348144T1 (https=)
AU (1) AU756211B2 (https=)
CA (1) CA2289023A1 (https=)
CY (1) CY1107557T1 (https=)
DE (1) DE69934366T2 (https=)
DK (1) DK0981600T3 (https=)
ES (1) ES2274619T3 (https=)
FI (1) FI980551A7 (https=)
PT (1) PT981600E (https=)
WO (1) WO1999046363A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
EP1097217A2 (en) * 1998-07-10 2001-05-09 Jens Nielsen Metabolically engineered microbial cell comprising a modified redox activity
EP1029919B1 (de) * 1999-02-20 2004-03-31 Degussa AG Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE19907347A1 (de) * 1999-02-20 2000-08-24 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
JP3965821B2 (ja) * 1999-03-09 2007-08-29 味の素株式会社 L−リジンの製造法
JP4380029B2 (ja) * 2000-07-05 2009-12-09 味の素株式会社 微生物を利用した物質の製造法
FI20010308A0 (fi) * 2001-02-16 2001-02-16 Valtion Teknillinen Sienen käsitteleminen geneettisesti siten, että se pystyy käyttämään L-arabinoosia
FI20012091A0 (fi) * 2001-10-29 2001-10-29 Valtion Teknillinen Sienimikro-organismi, jolla on parantunut suorituskyky bioteknisessä prosesseissa
DE10240603A1 (de) * 2002-09-03 2004-03-11 Degussa Ag Verwendung von Malat-Dehydrogenase zur NADH-Regenerierung
KR100786987B1 (ko) * 2004-01-30 2007-12-18 아지노모토 가부시키가이샤 L-아미노산 생산 미생물 및 l-아미노산 생산 방법
US8003367B2 (en) * 2004-03-16 2011-08-23 Ajinomoto Co., Inc. Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
US9523083B2 (en) * 2004-07-15 2016-12-20 Dsm Ip Assets B.V. Biochemical synthesis of 1,4-butanediamine
WO2008013996A2 (en) * 2006-07-27 2008-01-31 Gevo Inc. Engineered microorganisms for increasing product yield in biotransformations, related methods and systems
WO2009094614A1 (en) * 2008-01-25 2009-07-30 Novozymes A/S Producing fermentation products in the presence of aldehyde dehydrogenase
BRPI0913667A2 (pt) * 2008-02-20 2016-08-02 Nagarjuna Fertilizers And Chemicals Ltd microorganismos geneticamente transformados com aumento simultâneo de potencial de redução e atividades de enzima redutiva para fermentação de biomassa
US8563272B2 (en) 2008-06-27 2013-10-22 Edeniq, Inc. Cellulosic protein expression in yeast
US20100143997A1 (en) 2008-10-31 2010-06-10 Thomas Buelter Engineered microorganisms capable of producing target compounds under anaerobic conditions
US8198057B2 (en) * 2009-06-08 2012-06-12 Alternative Green Technologies, Llc Ethanol production by fermentation of chinese tallow tree
US11319558B2 (en) * 2009-10-28 2022-05-03 Province Brands Pichia stipitis strain, methods of using the same, and method of isolating a pichia stipitis strain
KR101645680B1 (ko) * 2009-11-06 2016-08-04 가부시키가이샤 한도오따이 에네루기 켄큐쇼 반도체 장치
CN103314101B (zh) 2010-11-03 2016-05-18 加利福尼亚大学董事会 通过蛋白质生物质发酵的重组微生物的生物燃料和化学生产
CN113717872A (zh) * 2021-09-27 2021-11-30 河北省微生物研究所有限公司 一种筛选高表达fad-gdh重组毕赤酵母菌株的方法
WO2025173696A1 (ja) * 2024-02-16 2025-08-21 株式会社カネカ ポリヒドロキシアルカン酸の製造方法、及び形質転換微生物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511656A (en) * 1981-05-15 1985-04-16 Purdue Research Foundation Direct fermentation of D-xylose to ethanol by a xylose-fermenting yeast mutant
US5424202A (en) * 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
US5487989A (en) * 1988-08-31 1996-01-30 Bioenergy International, L.C. Ethanol production by recombinant hosts
FI901771A7 (fi) * 1990-04-06 1991-10-07 Valtion Teknillinen Anvaendning av xylos hos hybridjaest.
SK283058B6 (sk) * 1993-10-28 2003-02-04 Ajinomoto Co., Inc. Spôsob produkcie cieľovej látky použitím mikroorganizmov
US5789210A (en) * 1993-11-08 1998-08-04 Purdue Research Foundation Recombinant yeasts for effective fermentation of glucose and xylose
IN191596B (https=) 1996-05-06 2003-12-06 Purdue Research Foundation

Also Published As

Publication number Publication date
DE69934366D1 (de) 2007-01-25
FI980551A7 (fi) 1999-09-12
DK0981600T3 (da) 2007-02-26
ES2274619T3 (es) 2007-05-16
CA2289023A1 (en) 1999-09-16
EP0981600B1 (en) 2006-12-13
AU756211B2 (en) 2003-01-09
EP0981600A1 (en) 2000-03-01
JP4573365B2 (ja) 2010-11-04
PT981600E (pt) 2007-02-28
CY1107557T1 (el) 2013-03-13
ATE348144T1 (de) 2007-01-15
WO1999046363A1 (en) 1999-09-16
US7091014B1 (en) 2006-08-15
JP2001525682A (ja) 2001-12-11
AU2730399A (en) 1999-09-27
FI980551A0 (fi) 1998-03-11

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