DE69933785D1 - Peptide enthaltend eine cholesterin-erkennungssequenz und deren verwendungen - Google Patents

Peptide enthaltend eine cholesterin-erkennungssequenz und deren verwendungen

Info

Publication number
DE69933785D1
DE69933785D1 DE69933785T DE69933785T DE69933785D1 DE 69933785 D1 DE69933785 D1 DE 69933785D1 DE 69933785 T DE69933785 T DE 69933785T DE 69933785 T DE69933785 T DE 69933785T DE 69933785 D1 DE69933785 D1 DE 69933785D1
Authority
DE
Germany
Prior art keywords
cholesterin
peptides contain
detector sequence
sequence
detector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69933785T
Other languages
English (en)
Other versions
DE69933785T2 (de
Inventor
Vassilios Papadopoulos
Hua Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgetown University
Original Assignee
Georgetown University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georgetown University filed Critical Georgetown University
Application granted granted Critical
Publication of DE69933785D1 publication Critical patent/DE69933785D1/de
Publication of DE69933785T2 publication Critical patent/DE69933785T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69933785T 1998-03-12 1999-03-12 Peptide enthaltend eine cholesterin-erkennungssequenz und deren verwendungen Expired - Fee Related DE69933785T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7775398P 1998-03-12 1998-03-12
US77753P 1998-03-12
PCT/US1999/005853 WO1999046575A2 (en) 1998-03-12 1999-03-12 Peptides containing a cholesterol recognition sequence and their uses

Publications (2)

Publication Number Publication Date
DE69933785D1 true DE69933785D1 (de) 2006-12-07
DE69933785T2 DE69933785T2 (de) 2007-10-04

Family

ID=22139865

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933785T Expired - Fee Related DE69933785T2 (de) 1998-03-12 1999-03-12 Peptide enthaltend eine cholesterin-erkennungssequenz und deren verwendungen

Country Status (8)

Country Link
EP (1) EP1129112B1 (de)
JP (1) JP2003521223A (de)
AT (1) ATE343595T1 (de)
AU (2) AU776298B2 (de)
CA (1) CA2327329A1 (de)
DE (1) DE69933785T2 (de)
ES (1) ES2274621T3 (de)
WO (1) WO1999046575A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE512674T1 (de) 2003-01-06 2011-07-15 Angiochem Inc Angiopep-1, verwandte verbindungen, und deren verwnedungen
WO2007136819A2 (en) * 2006-05-19 2007-11-29 Georgetown University Use of peptides containing a cholesterol interaction sequence for treating hypercholesterolemia, viral infection, obesity and diabetes
EP2074142A4 (de) * 2006-10-19 2010-10-27 Angiochem Inc Verbindungen zur stimulierung der funktion von p-glykoprotein und anwendungen davon
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
BRPI0920209A2 (pt) 2008-10-15 2015-12-22 Angiochem Inc conjugados de agonistas de glp-1 e usos dos mesmos
CA2989400A1 (en) 2015-06-15 2016-12-22 Angiochem Inc. Ang1005 for the treatment of leptomeningeal carcinomatosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5708145A (en) * 1993-07-20 1998-01-13 University Of California Immunglobulins reactive with protegrins
US5994306A (en) * 1995-11-22 1999-11-30 Intrabiotics Pharmaceuticals, Inc. Fine-tuned protegrins
ES2241268T3 (es) * 1998-03-11 2005-10-16 Immunomedics, Inc. Onconasa recombinante y proteinas de fusion de onconasa recombinante.

Also Published As

Publication number Publication date
WO1999046575A3 (en) 2001-06-28
AU2004235618A1 (en) 2005-01-06
WO1999046575A2 (en) 1999-09-16
EP1129112A2 (de) 2001-09-05
AU2004235618B2 (en) 2007-10-11
CA2327329A1 (en) 1999-09-16
AU3096899A (en) 1999-09-27
ATE343595T1 (de) 2006-11-15
DE69933785T2 (de) 2007-10-04
JP2003521223A (ja) 2003-07-15
ES2274621T3 (es) 2007-05-16
EP1129112B1 (de) 2006-10-25
AU776298B2 (en) 2004-09-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee