DE69933472D1 - Pulmonale arzneistoffverabreichung - Google Patents

Pulmonale arzneistoffverabreichung

Info

Publication number
DE69933472D1
DE69933472D1 DE69933472T DE69933472T DE69933472D1 DE 69933472 D1 DE69933472 D1 DE 69933472D1 DE 69933472 T DE69933472 T DE 69933472T DE 69933472 T DE69933472 T DE 69933472T DE 69933472 D1 DE69933472 D1 DE 69933472D1
Authority
DE
Germany
Prior art keywords
formulation
disabling
pulmonary drug
pulmonary
dispenser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69933472T
Other languages
English (en)
Other versions
DE69933472T2 (de
Inventor
Pankaj Modi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Generex Pharmaceuticals Inc
Original Assignee
Generex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Generex Pharmaceuticals Inc filed Critical Generex Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69933472D1 publication Critical patent/DE69933472D1/de
Publication of DE69933472T2 publication Critical patent/DE69933472T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
DE69933472T 1998-12-21 1999-12-16 Pulmonale arzneistoffverabreichung Expired - Lifetime DE69933472T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US397102 1989-08-21
US11324398P 1998-12-21 1998-12-21
US113243P 1998-12-21
US09/397,102 US6294153B1 (en) 1998-12-21 1999-09-16 Aerosol pharmaceutical formulation for pulmonary and nasal delivery
PCT/CA1999/001232 WO2000037052A1 (en) 1998-12-21 1999-12-16 Pulmonary drug delivery

Publications (2)

Publication Number Publication Date
DE69933472D1 true DE69933472D1 (de) 2006-11-16
DE69933472T2 DE69933472T2 (de) 2007-05-31

Family

ID=26810843

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933472T Expired - Lifetime DE69933472T2 (de) 1998-12-21 1999-12-16 Pulmonale arzneistoffverabreichung

Country Status (13)

Country Link
US (1) US6294153B1 (de)
EP (1) EP1143931B1 (de)
JP (1) JP3818852B2 (de)
AT (1) ATE341309T1 (de)
AU (1) AU759051B2 (de)
CA (1) CA2353847C (de)
DE (1) DE69933472T2 (de)
DK (1) DK1143931T3 (de)
ES (1) ES2274651T3 (de)
MX (1) MXPA01006377A (de)
NZ (1) NZ512272A (de)
PT (1) PT1143931E (de)
WO (1) WO2000037052A1 (de)

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US6350432B1 (en) * 1999-03-19 2002-02-26 Generex Pharmaceuticals Incorporated Pressurized container having an aerosolized pharmaceutical composition
EP1575976A4 (de) 2001-11-02 2006-08-23 Insert Therapeutics Inc Verfahren und zusammensetzungen zur therapeutischen verwendung von rna-interferenz
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US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP1631308B1 (de) * 2003-05-30 2013-07-31 Amylin Pharmaceuticals, LLC Neue verfahren und zusammensetzungen für die verbesserte transmukosale abgabe von peptiden und proteinen
WO2005065185A2 (en) * 2003-12-24 2005-07-21 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
US20090069226A1 (en) * 2004-05-28 2009-03-12 Amylin Pharmaceuticals, Inc. Transmucosal delivery of peptides and proteins
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
EP2486942B1 (de) 2004-11-24 2018-10-10 Meda Pharmaceuticals Inc. Zusammensetzungen mit azelastin und anwendungsverfahren
DK1866414T3 (da) 2005-03-31 2012-04-23 Calando Pharmaceuticals Inc Inhibitorer af ribonukleotidreduktase-underenhed 2 og anvendelser deraf.
US20070197460A1 (en) * 2005-11-01 2007-08-23 Alnylam Pharmaceuticals, Inc. Rnai inhibition of influenza virus replication
US8229398B2 (en) * 2006-01-30 2012-07-24 Qualcomm Incorporated GSM authentication in a CDMA network
US7846908B2 (en) * 2006-03-16 2010-12-07 Alnylam Pharmaceuticals, Inc. RNAi modulation of TGF-beta and therapeutic uses thereof
WO2007127163A2 (en) * 2006-04-24 2007-11-08 Geron Corporation Cns-tumor treatment method and composition
CA2652770A1 (en) 2006-05-19 2007-11-29 Alnylam Pharmaceuticals, Inc. Rnai modulation of aha and therapeutic uses thereof
US20140147441A1 (en) * 2006-09-12 2014-05-29 The General Hospital Corporation Compositions containing alpha-1-antitrypsin and methods for use
WO2009015037A2 (en) 2007-07-21 2009-01-29 Albany Molecular Research, Inc. 5-pyridinone substituted indazoles
WO2009023803A2 (en) * 2007-08-15 2009-02-19 Abbott Respiratory Llc Modulated release formulation for the delivery of one or more medicaments
EP2628727A3 (de) 2007-11-21 2013-12-25 Decode Genetics EHF Biaryl-PDE4-Inhibitoren zur Behandlung von Lungen- und Herz-Kreislauferkrankungen
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JP2011511674A (ja) 2008-02-07 2011-04-14 ユニヴァーシティ オブ ワシントン 周方向エアロゾルデバイス
CN102037123A (zh) 2008-04-04 2011-04-27 卡兰多制药股份有限公司 Epas1抑制剂的组合物和用途
WO2010059836A1 (en) 2008-11-20 2010-05-27 Decode Genetics Ehf Substituted aza-bridged bicyclics for cardiovascular and cns disease
RU2506266C2 (ru) 2009-01-26 2014-02-10 Израэл Инститьют Фо Байолоджикал Рисерч Бициклические гетероциклические спиросоединения
EP2504019A2 (de) 2009-11-25 2012-10-03 ArisGen SA Zusammensetzung zur verabreichung über die schleimhaut mit einem komplex aus einem peptid und einer kronenverbindung und/oder einem gegenion
EP2605816B1 (de) * 2010-08-20 2019-01-23 University Of Washington Umlaufende aerosolvorrichtung zur abgabe von arzneimitteln an die riechschleimhaut und das gehirn
BR122021002471B8 (pt) 2011-03-03 2022-10-25 Impel Neuropharma Inc Dispositivo de distribuição de droga nasal
CN107376071B (zh) 2011-05-09 2021-07-09 英倍尔药业股份有限公司 用于将化合物递送到使用者的上部嗅觉区的喷嘴
RU2657523C2 (ru) * 2011-11-03 2018-06-14 Олег Петрович Жирнов Фармацевтический аэрозольный состав ингибиторов протеаз с озон-сберегающим пропеллентом и его получение
EP2991713B1 (de) 2013-04-28 2019-06-19 Impel Neuropharma Inc. Medizinischer einzeldosisbehälter
WO2015069897A1 (en) 2013-11-07 2015-05-14 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Red blood cell membrane-derived microparticles and their use for the treatment of lung disease
JP6753927B2 (ja) 2015-09-10 2020-09-09 インペル ニューロファーマ インコーポレイテッド 直列形経鼻送達デバイス
EP3713628A4 (de) 2017-11-21 2021-08-18 Impel Neuropharma Inc. Intranasale vorrichtung mit tauchrohr
CA3081680A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with inlet interface
JP2021509677A (ja) 2018-01-05 2021-04-01 インペル ニューロファーマ インコーポレイテッド 精密嗅覚装置によるオランザピンの鼻孔間送達
CA3088942C (en) 2018-01-05 2023-01-03 Impel Neuropharma, Inc. Intranasal delivery of dihydroergotamine by precision olfactory device
JP2021518413A (ja) 2018-03-20 2021-08-02 アイカーン スクール オブ メディシン アット マウント サイナイ キナーゼ阻害剤化合物及び組成物ならびに使用方法
US11517548B2 (en) 2018-07-19 2022-12-06 Impel Pharmaceuticals Inc. Respiratory tract delivery of levodopa and DOPA decarboxylase inhibitor for treatment of Parkinson's Disease
JP2021536467A (ja) 2018-09-06 2021-12-27 インノファーマスクリーン インコーポレイテッド 喘息またはパーキンソン病の処置のための方法および組成物
EP3906233B1 (de) 2018-12-31 2024-01-31 Icahn School of Medicine at Mount Sinai Kinaseinhibitorverbindungen und zusammensetzungen und verfahren zur verwendung
EP3906017A4 (de) 2019-01-03 2022-12-28 Impel Pharmaceuticals Inc. Vorrichtung für nasale wirkstofffreisetzung
US11878109B2 (en) 2019-05-17 2024-01-23 Impel Pharmaceuticals Inc. Single-use nasal delivery device
US20240117019A1 (en) 2021-02-09 2024-04-11 University Of Georgia Research Foundation, Inc. Human monoclonal antibodies against pneumococcal antigens
WO2023198757A1 (en) 2022-04-14 2023-10-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Alpha-1-antitrypsin for treating paramyxoviridae or orthomyxoviridae infections

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Also Published As

Publication number Publication date
NZ512272A (en) 2002-12-20
MXPA01006377A (es) 2002-05-06
US6294153B1 (en) 2001-09-25
WO2000037052A1 (en) 2000-06-29
DE69933472T2 (de) 2007-05-31
PT1143931E (pt) 2007-01-31
AU1851900A (en) 2000-07-12
JP2002532537A (ja) 2002-10-02
ES2274651T3 (es) 2007-05-16
AU759051B2 (en) 2003-04-03
CA2353847A1 (en) 2000-06-29
EP1143931A1 (de) 2001-10-17
JP3818852B2 (ja) 2006-09-06
DK1143931T3 (da) 2007-02-12
CA2353847C (en) 2007-03-06
EP1143931B1 (de) 2006-10-04
ATE341309T1 (de) 2006-10-15

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Legal Events

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