AR022374A1 - Sistema de suministro de medicacion de goma de mascar para nicotina - Google Patents
Sistema de suministro de medicacion de goma de mascar para nicotinaInfo
- Publication number
- AR022374A1 AR022374A1 ARP990104461A ARP990104461A AR022374A1 AR 022374 A1 AR022374 A1 AR 022374A1 AR P990104461 A ARP990104461 A AR P990104461A AR P990104461 A ARP990104461 A AR P990104461A AR 022374 A1 AR022374 A1 AR 022374A1
- Authority
- AR
- Argentina
- Prior art keywords
- minutes
- nicotine
- active
- supply system
- provides
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Confectionery (AREA)
Abstract
Un sistema de suministro de goma de mascar que tiene nicotina, goma base y un sistema buffer, con un perfeccionado índice de liberacion para la nicotina.El sistema de suministro resultante proporciona convenientemente un sistema conveniente, confiable, práctico y relativamente indoloro para el suministro de unactivo. El sistema de suministro es capaz de suministrar dosis iniciales y secundarias de un activo reductor del deseo, y otros activos (por ejemplo, nicotina), cuya combinacion rápidamentereduce los deseos, o proporciona algun otro efecto farmacologico, y proporciona el efecto farmacologico o proteccion contradichos deseos durante un período de tiempo prolongado más allá de la dosis inicial. Cabe observarse que el sistema de suministro es capaz de lograr rápidamenteuna concentracion farmacologicamente efectiva del activo (por ejemplo, nicotina) en la corriente sanguínea (por ejemplo, dentro de los 5 minutos o con másconveniencia dentro de los 3 minutos, o en algunos casos, dentro de 1-2 minutos), y además es capaz de mantener la concentracion del activo en la corrientesanguínea a la concentracion farmacologicamente efectiva, o cerca de ella, durante por lo menos 20 minutos después de que comienza el mascado del sistema desuministro, o con más conveniencia, aproximadamente 30 minutos a aproximadamente 50 minutos después de que comienza el mascado.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/146,696 US6358060B2 (en) | 1998-09-03 | 1998-09-03 | Two-stage transmucosal medicine delivery system for symptom relief |
| IE980991 | 1998-11-27 | ||
| US36089699A | 1999-07-26 | 1999-07-26 | |
| US09/389,339 US6344222B1 (en) | 1998-09-03 | 1999-09-02 | Medicated chewing gum delivery system for nicotine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR022374A1 true AR022374A1 (es) | 2002-09-04 |
Family
ID=27270586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990104461A AR022374A1 (es) | 1998-09-03 | 1999-09-03 | Sistema de suministro de medicacion de goma de mascar para nicotina |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR022374A1 (es) |
| DE (1) | DE69938347T2 (es) |
| DK (1) | DK1107730T3 (es) |
| MY (1) | MY124346A (es) |
-
1999
- 1999-09-03 AR ARP990104461A patent/AR022374A1/es unknown
- 1999-09-03 DE DE69938347T patent/DE69938347T2/de not_active Expired - Lifetime
- 1999-09-03 MY MYPI99003826A patent/MY124346A/en unknown
- 1999-09-03 DK DK99946722T patent/DK1107730T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69938347D1 (de) | 2008-04-24 |
| DE69938347T2 (de) | 2009-04-23 |
| DK1107730T3 (da) | 2008-07-14 |
| MY124346A (en) | 2006-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |