DE69924026D1 - Coenzym zur herstellung von l-carnitin - Google Patents

Coenzym zur herstellung von l-carnitin

Info

Publication number
DE69924026D1
DE69924026D1 DE69924026T DE69924026T DE69924026D1 DE 69924026 D1 DE69924026 D1 DE 69924026D1 DE 69924026 T DE69924026 T DE 69924026T DE 69924026 T DE69924026 T DE 69924026T DE 69924026 D1 DE69924026 D1 DE 69924026D1
Authority
DE
Germany
Prior art keywords
carnitine
preparation
coenzym
coenzyme
butyrobetainyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69924026T
Other languages
English (en)
Other versions
DE69924026T2 (de
Inventor
Thomas Elssner
Hans-Peter Kleber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1998150426 external-priority patent/DE19850426A1/de
Priority claimed from DE1998150433 external-priority patent/DE19850433A1/de
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority to DE69924026T priority Critical patent/DE69924026T2/de
Application granted granted Critical
Publication of DE69924026D1 publication Critical patent/DE69924026D1/de
Publication of DE69924026T2 publication Critical patent/DE69924026T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/007—Carnitine; Butyrobetaine; Crotonobetaine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE69924026T 1998-10-27 1999-10-22 Coenzym zur herstellung von l-carnitin Expired - Fee Related DE69924026T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE69924026T DE69924026T2 (de) 1998-10-27 1999-10-22 Coenzym zur herstellung von l-carnitin

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19850426 1998-10-27
DE19850433 1998-10-27
DE1998150426 DE19850426A1 (de) 1998-10-27 1998-10-27 gamma-Butyrobetainyl-Coenzym A und Verfahren zu seiner Herstellung
DE1998150433 DE19850433A1 (de) 1998-10-27 1998-10-27 Crotonobetainyl-Coenzym A, Verfahren zu seiner Herstellung
DE69924026T DE69924026T2 (de) 1998-10-27 1999-10-22 Coenzym zur herstellung von l-carnitin
PCT/IT1999/000339 WO2000024919A1 (en) 1998-10-27 1999-10-22 Coenzymes useful for the synthesis of l-carnitine

Publications (2)

Publication Number Publication Date
DE69924026D1 true DE69924026D1 (de) 2005-04-07
DE69924026T2 DE69924026T2 (de) 2006-02-09

Family

ID=26049898

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69924026T Expired - Fee Related DE69924026T2 (de) 1998-10-27 1999-10-22 Coenzym zur herstellung von l-carnitin

Country Status (11)

Country Link
US (2) US6379936B1 (de)
EP (2) EP1151130B1 (de)
JP (1) JP2002528468A (de)
AT (1) ATE290096T1 (de)
AU (1) AU1075400A (de)
DE (1) DE69924026T2 (de)
DK (1) DK1151130T3 (de)
ES (1) ES2237954T3 (de)
PT (1) PT1151130E (de)
SI (1) SI1151130T1 (de)
WO (1) WO2000024919A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001079530A1 (de) * 2000-04-17 2001-10-25 Befa Handelsgesellschaft M.B.H. Verfahren zur bestimmung der konzentration von carnitin in flüssigen substanzen
US7700074B2 (en) * 2002-02-07 2010-04-20 Pettegrew Jay W Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
US7407778B2 (en) * 2002-02-07 2008-08-05 Pettegrew Jay W Compounds, compositions and methods for treating neuropsychiatric disorders
US20060257842A1 (en) * 2003-05-29 2006-11-16 Pettegrew Jay W Cryopreservation media and molecules
EP1641806B1 (de) * 2003-05-29 2009-07-29 Jay W. Pettegrew Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
KR100713104B1 (ko) * 2005-07-07 2007-05-02 씨제이 주식회사 뉴로스포라 크라사 유래의ｓ-아데노실메티오닌-6-ｎ-라이신-메틸트란스퍼라제, 그를코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를포함하는 벡터 및 숙주세포 및 상기 숙주세포를 이용하여트리메틸라이신을 생산하는 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1142201B (it) 1980-06-24 1986-10-08 Sigma Tau Ind Farmaceuti Procedimento per la produzione enzimatica di l-carnitina
DD221905B1 (de) 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
ES2051890T3 (es) 1987-10-26 1994-07-01 Sigma Tau Ind Farmaceuti Procedimiento para aislar la enzima carnitinhidroliasa de cepas pertenecientes a la familia enterobacteriaceae y empleo de la enzima inmobilizada para producir l(-)-carnitina.
IT1240833B (it) 1990-05-14 1993-12-17 Sigma Tau Ind Farmaceuti Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento
CZ288247B6 (en) * 1993-10-08 2001-05-16 Lonza Ag DNA fragment, vector a microorganism containing genes for metabolic transformation of butyrobetaine/crotonobetaine-L-carnitine and process for preparing L-carnitine
FR2715167B1 (fr) * 1994-01-20 1996-04-12 Inst Nat Sciences Appliq Lyon Procédé de production de la L-carnitine par voie microbiologique.
DE4402127A1 (de) * 1994-01-21 1995-07-27 Univ Leipzig Carnitinracemase und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
DE69924026T2 (de) 2006-02-09
AU1075400A (en) 2000-05-15
ATE290096T1 (de) 2005-03-15
ES2237954T3 (es) 2005-08-01
DK1151130T3 (da) 2005-06-20
US20020146787A1 (en) 2002-10-10
SI1151130T1 (en) 2005-06-30
US6562608B2 (en) 2003-05-13
US6379936B1 (en) 2002-04-30
EP1151130B1 (de) 2005-03-02
PT1151130E (pt) 2005-06-30
EP1452604A2 (de) 2004-09-01
EP1452604A3 (de) 2005-03-30
JP2002528468A (ja) 2002-09-03
WO2000024919A1 (en) 2000-05-04
EP1151130A1 (de) 2001-11-07

Similar Documents

Publication Publication Date Title
DE69908998D1 (de) Verfahren zur Herstellung von Kohlenstoff
DE60006298D1 (de) Verfahren zur Herstellung von Kohlendioxid
DE69835357D1 (de) Verfahren zur Herstellung von Synthesegas
CA2390867A1 (en) Method for the production of biopolymers with modified properties
DE60201498D1 (de) Verbesserter prozess zur herstellung von carbapenemen
DE69509705D1 (de) Vorläufersubstanz zur Herstellung von SiO2TiO2
DE1169296T1 (de) Niedrigdruckreaktor zur herstellung von aminen
ATE290096T1 (de) Coenzym zur herstellung von l-carnitin
DE60018173D1 (de) Giessform zur herstellung eines kühlelementes
DE29908237U1 (de) Werkzeug zur Herstellung von unregelmäßig gekrümmten Blechen
DE60100217D1 (de) Verfahren zur Herstellung von hochkonzentrierten Kohlendioxid
DE69822711D1 (de) Verfarhen zur Herstellung von Dialkylnaphthalinen
DE69906074T2 (de) Verfahren zur herstellung von 3-aryl-benzofuranonen
DE60224884D1 (de) Verfahren zur herstellung von 3, 3', 6, 6'-tetraalkylen-2, 2'-biphenolen und 3, 3', 6, 6'-tetraalkylen-5, 5'-dihalo-2, 2' biphenolen
DE60222806D1 (de) Verfahren zur herstellung von (1,4,5)-oxadiazepinderivaten
DE69812438T2 (de) Zusammensetzung zur herstellung von brennstoff-briketts
DE69610747T2 (de) Verfahren zur Herstellung von hochreinem 2,4'-Dihydroxydiphenylsulfon
ATE251132T1 (de) Verfahren zur herstellung von s-aryl-l-cystein und derivate
DE50109809D1 (de) Verfahren zur Herstellung von D- oder L-Menthol
ATE268753T1 (de) Verfahren zur herstellung von 24(s)- hydroxyvitamin d2
DE60230097D1 (de) Verfahren zur herstellung von 1,5-diaminonaphthalinen
DE59900891D1 (de) Werkzeug zur Herstellung strukturierter Bleche
DE60208551D1 (de) Verfahren zur herstellung von racemischen und enantiomerenreinen derivaten von 1,5-diaryl-3-trifluormethyl-delta2-pyrazolinen
DE59900401D1 (de) Verfahren zur Herstellung von 1,3-Dimethyl-imidazolium-4-carboxylat
DE69801454T2 (de) Verfahren zur Herstellung von 2-Methyl-1,4-Benzochinon

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee