DE69920224D1 - Harnstoffderivate zur Schmerzbekämpfung - Google Patents

Harnstoffderivate zur Schmerzbekämpfung

Info

Publication number
DE69920224D1
DE69920224D1 DE69920224T DE69920224T DE69920224D1 DE 69920224 D1 DE69920224 D1 DE 69920224D1 DE 69920224 T DE69920224 T DE 69920224T DE 69920224 T DE69920224 T DE 69920224T DE 69920224 D1 DE69920224 D1 DE 69920224D1
Authority
DE
Germany
Prior art keywords
pain relief
urea derivatives
urea
derivatives
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69920224T
Other languages
English (en)
Other versions
DE69920224T2 (de
Inventor
Daniel Delorme
Vlad Gregor
Edward Roberts
Eric Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE69920224D1 publication Critical patent/DE69920224D1/de
Publication of DE69920224T2 publication Critical patent/DE69920224T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0404Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69920224T 1998-06-22 1999-06-16 Harnstoffderivate zur Schmerzbekämpfung Expired - Fee Related DE69920224T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9802209 1998-06-22
SE9802209A SE9802209D0 (sv) 1998-06-22 1998-06-22 Novel compounds
PCT/SE1999/001075 WO1999067204A1 (en) 1998-06-22 1999-06-16 Novel compounds

Publications (2)

Publication Number Publication Date
DE69920224D1 true DE69920224D1 (de) 2004-10-21
DE69920224T2 DE69920224T2 (de) 2005-10-13

Family

ID=20411787

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69920224T Expired - Fee Related DE69920224T2 (de) 1998-06-22 1999-06-16 Harnstoffderivate zur Schmerzbekämpfung

Country Status (11)

Country Link
US (2) US6777561B1 (de)
EP (1) EP1089965B1 (de)
AR (1) AR029302A1 (de)
AT (1) ATE276234T1 (de)
AU (1) AU4814699A (de)
CA (1) CA2335528A1 (de)
DE (1) DE69920224T2 (de)
ES (1) ES2228066T3 (de)
PT (1) PT1089965E (de)
SE (1) SE9802209D0 (de)
WO (1) WO1999067204A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9917038A (pt) * 1998-12-18 2002-04-02 Du Pont Pharm Co Composto, composição farmacêutica, método de modulação da atividade receptora de quimocinas, método de tratamento ou prevenção de doenças inflamatórias, método de tratamento ou prevenção de asma e método de tratamento ou prevenção de disfunções inflamatórias
WO2000035449A1 (en) * 1998-12-18 2000-06-22 Du Pont Pharmaceuticals Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6331541B1 (en) 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6525069B1 (en) 1998-12-18 2003-02-25 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
EP1140087A4 (de) 1998-12-18 2002-04-03 Du Pont Pharm Co N-ureidoalkyl-piperidine als modulatoren der chemokin-rezeptor-aktivität
US6897234B2 (en) 1999-12-17 2005-05-24 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
WO2001098270A2 (en) * 2000-06-21 2001-12-27 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
AR034257A1 (es) 2000-06-30 2004-02-18 Du Pont Pharm Co Compuesto ureido, composicion farmaceutica que lo comprende y metodo para modular la actividad del receptor de quimiocinas
KR100634195B1 (ko) 2002-08-30 2006-10-16 니뽄 다바코 산교 가부시키가이샤 디벤질아민 화합물 및 그 의약 용도
ES2305491T3 (es) * 2002-09-19 2008-11-01 Eli Lilly And Company Eteres de diarilo como antagonistas de receptores de opioides.
SG172060A1 (en) * 2008-12-09 2011-07-28 Gilead Sciences Inc Modulators of toll-like receptors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH441366A (de) * 1961-06-09 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von substituierten Hydrazinverbindungen
NL7800026A (nl) * 1977-01-07 1978-07-11 Acna Werkwijze voor de bereiding van gesubstitueerde amino-benzenen.
EP0144853B1 (de) * 1983-11-21 1990-09-26 Fujisawa Pharmaceutical Co., Ltd. Semicarbazid-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
CN1021819C (zh) * 1988-01-20 1993-08-18 山之内制药株式会社 作为药物有用的双脲衍生物的制备方法
TW209868B (de) * 1991-04-04 1993-07-21 Yoshitomi Pharmaceutical
GB9511355D0 (en) * 1995-06-06 1995-08-02 Fujisawa Pharmaceutical Co Urea derivatives
DE19544687A1 (de) * 1995-11-30 1997-06-05 Thomae Gmbh Dr K Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5866609A (en) * 1996-08-09 1999-02-02 Ss Pharmaceutical Co., Ltd. Substituted vinylurea derivatives and medicine containing the same
DE69826695T2 (de) 1997-05-23 2006-02-02 Bayer Pharmaceuticals Corp., West Haven Arylharnstoffderivate zur behandlung von inflammatorischen oder immunomodulatorischen erkrankungen

Also Published As

Publication number Publication date
ATE276234T1 (de) 2004-10-15
AU4814699A (en) 2000-01-10
WO1999067204A1 (en) 1999-12-29
CA2335528A1 (en) 1999-12-29
EP1089965B1 (de) 2004-09-15
DE69920224T2 (de) 2005-10-13
US6777561B1 (en) 2004-08-17
EP1089965A1 (de) 2001-04-11
US20050032789A1 (en) 2005-02-10
PT1089965E (pt) 2004-12-31
ES2228066T3 (es) 2005-04-01
SE9802209D0 (sv) 1998-06-22
AR029302A1 (es) 2003-06-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee