PT1089965E - Derivados de ureia para tratamento da dor - Google Patents

Derivados de ureia para tratamento da dor

Info

Publication number
PT1089965E
PT1089965E PT99931710T PT99931710T PT1089965E PT 1089965 E PT1089965 E PT 1089965E PT 99931710 T PT99931710 T PT 99931710T PT 99931710 T PT99931710 T PT 99931710T PT 1089965 E PT1089965 E PT 1089965E
Authority
PT
Portugal
Prior art keywords
ureia
derivatives
pain treatment
pain
treatment
Prior art date
Application number
PT99931710T
Other languages
English (en)
Inventor
Delorme Daniel
Gregor Vlad
Roberts Edward
Sun Eric
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT1089965E publication Critical patent/PT1089965E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0404Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT99931710T 1998-06-22 1999-06-16 Derivados de ureia para tratamento da dor PT1089965E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9802209A SE9802209D0 (sv) 1998-06-22 1998-06-22 Novel compounds

Publications (1)

Publication Number Publication Date
PT1089965E true PT1089965E (pt) 2004-12-31

Family

ID=20411787

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99931710T PT1089965E (pt) 1998-06-22 1999-06-16 Derivados de ureia para tratamento da dor

Country Status (11)

Country Link
US (2) US6777561B1 (pt)
EP (1) EP1089965B1 (pt)
AR (1) AR029302A1 (pt)
AT (1) ATE276234T1 (pt)
AU (1) AU4814699A (pt)
CA (1) CA2335528A1 (pt)
DE (1) DE69920224T2 (pt)
ES (1) ES2228066T3 (pt)
PT (1) PT1089965E (pt)
SE (1) SE9802209D0 (pt)
WO (1) WO1999067204A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525069B1 (en) 1998-12-18 2003-02-25 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6331541B1 (en) 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
AU2482100A (en) * 1998-12-18 2000-07-03 Du Pont Pharmaceuticals Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6492400B1 (en) 1998-12-18 2002-12-10 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
JP2002532427A (ja) * 1998-12-18 2002-10-02 デュポン ファーマシューティカルズ カンパニー ケモカイン受容体活性のモジュレーターとしてのn−ウレイドアルキルピペリジン
US6897234B2 (en) 1999-12-17 2005-05-24 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
CA2413421A1 (en) * 2000-06-21 2001-12-27 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
AU2001273129A1 (en) 2000-06-30 2002-01-14 Bristol-Myers Squibb Pharma Company N-ureidoheterocycloaklyl-piperidines as modulators of chemokine receptor activity
CN1289467C (zh) 2002-08-30 2006-12-13 日本烟草产业株式会社 二苄胺化合物及其药物用途
US7381719B2 (en) * 2002-09-19 2008-06-03 Eli Lilly And Company Diaryl ethers as opioid receptor antagonist
EA021377B9 (ru) * 2008-12-09 2015-09-30 Джилид Сайэнс, Инк. Модуляторы толл-подобных рецепторов

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH441366A (de) 1961-06-09 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von substituierten Hydrazinverbindungen
NL7800026A (nl) * 1977-01-07 1978-07-11 Acna Werkwijze voor de bereiding van gesubstitueerde amino-benzenen.
EP0144853B1 (en) * 1983-11-21 1990-09-26 Fujisawa Pharmaceutical Co., Ltd. Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
CN1021819C (zh) * 1988-01-20 1993-08-18 山之内制药株式会社 作为药物有用的双脲衍生物的制备方法
TW209868B (pt) * 1991-04-04 1993-07-21 Yoshitomi Pharmaceutical
GB9511355D0 (en) 1995-06-06 1995-08-02 Fujisawa Pharmaceutical Co Urea derivatives
DE19544687A1 (de) * 1995-11-30 1997-06-05 Thomae Gmbh Dr K Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5866609A (en) * 1996-08-09 1999-02-02 Ss Pharmaceutical Co., Ltd. Substituted vinylurea derivatives and medicine containing the same
WO1998052558A1 (en) 1997-05-23 1998-11-26 Bayer Corporation INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS

Also Published As

Publication number Publication date
US20050032789A1 (en) 2005-02-10
DE69920224D1 (de) 2004-10-21
EP1089965A1 (en) 2001-04-11
ATE276234T1 (de) 2004-10-15
CA2335528A1 (en) 1999-12-29
AU4814699A (en) 2000-01-10
US6777561B1 (en) 2004-08-17
WO1999067204A1 (en) 1999-12-29
SE9802209D0 (sv) 1998-06-22
DE69920224T2 (de) 2005-10-13
ES2228066T3 (es) 2005-04-01
EP1089965B1 (en) 2004-09-15
AR029302A1 (es) 2003-06-25

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