ATE276234T1 - Harnstoffderivate zur schmerzbekämpfung - Google Patents

Harnstoffderivate zur schmerzbekämpfung

Info

Publication number
ATE276234T1
ATE276234T1 AT99931710T AT99931710T ATE276234T1 AT E276234 T1 ATE276234 T1 AT E276234T1 AT 99931710 T AT99931710 T AT 99931710T AT 99931710 T AT99931710 T AT 99931710T AT E276234 T1 ATE276234 T1 AT E276234T1
Authority
AT
Austria
Prior art keywords
fighting
pain
urea derivatives
urea
derivatives
Prior art date
Application number
AT99931710T
Other languages
English (en)
Inventor
Daniel Methylgene Inc Delorme
Vlad Gregor
Edward Roberts
Eric Alanex Corp Sun
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE276234T1 publication Critical patent/ATE276234T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0404Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99931710T 1998-06-22 1999-06-16 Harnstoffderivate zur schmerzbekämpfung ATE276234T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9802209A SE9802209D0 (sv) 1998-06-22 1998-06-22 Novel compounds
PCT/SE1999/001075 WO1999067204A1 (en) 1998-06-22 1999-06-16 Novel compounds

Publications (1)

Publication Number Publication Date
ATE276234T1 true ATE276234T1 (de) 2004-10-15

Family

ID=20411787

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99931710T ATE276234T1 (de) 1998-06-22 1999-06-16 Harnstoffderivate zur schmerzbekämpfung

Country Status (11)

Country Link
US (2) US6777561B1 (de)
EP (1) EP1089965B1 (de)
AR (1) AR029302A1 (de)
AT (1) ATE276234T1 (de)
AU (1) AU4814699A (de)
CA (1) CA2335528A1 (de)
DE (1) DE69920224T2 (de)
ES (1) ES2228066T3 (de)
PT (1) PT1089965E (de)
SE (1) SE9802209D0 (de)
WO (1) WO1999067204A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3126700A (en) * 1998-12-18 2000-07-03 Du Pont Pharmaceuticals Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6525069B1 (en) 1998-12-18 2003-02-25 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6331541B1 (en) 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
CA2346933A1 (en) * 1998-12-18 2000-06-22 Dupont Pharmaceuticals Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
WO2000035452A1 (en) * 1998-12-18 2000-06-22 Du Pont Pharmaceuticals Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6897234B2 (en) 1999-12-17 2005-05-24 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
CA2413421A1 (en) * 2000-06-21 2001-12-27 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
CA2413245A1 (en) 2000-06-30 2002-01-10 Bristol-Myers Squibb Pharma Company N-ureidoheterocycloaklyl-piperidines as modulators of chemokine receptor activity
EP1533292B1 (de) 2002-08-30 2007-02-14 Japan Tobacco Inc. Dibenzylaminverbindung und deren medizinische verwendung
DK1562595T3 (da) * 2002-09-19 2008-08-18 Lilly Co Eli Diarylethere som opioidreceptorantagonister
UY32306A (es) * 2008-12-09 2010-07-30 Gilead Sciences Inc Derivados de pteridinona y pirimidinodiazepinona y composiciones farmacéuticas que modulan en forma selectiva los receptores tipo toll, métodos y usos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH441366A (de) * 1961-06-09 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von substituierten Hydrazinverbindungen
NL7800026A (nl) * 1977-01-07 1978-07-11 Acna Werkwijze voor de bereiding van gesubstitueerde amino-benzenen.
EP0144853B1 (de) * 1983-11-21 1990-09-26 Fujisawa Pharmaceutical Co., Ltd. Semicarbazid-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
CN1021819C (zh) * 1988-01-20 1993-08-18 山之内制药株式会社 作为药物有用的双脲衍生物的制备方法
TW209868B (de) * 1991-04-04 1993-07-21 Yoshitomi Pharmaceutical
GB9511355D0 (en) 1995-06-06 1995-08-02 Fujisawa Pharmaceutical Co Urea derivatives
DE19544687A1 (de) * 1995-11-30 1997-06-05 Thomae Gmbh Dr K Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5770615A (en) * 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5866609A (en) * 1996-08-09 1999-02-02 Ss Pharmaceutical Co., Ltd. Substituted vinylurea derivatives and medicine containing the same
DE1019040T1 (de) * 1997-05-23 2001-02-08 Bayer Ag Hemmung von p38 kinase aktivität durch arylharnstoff

Also Published As

Publication number Publication date
US6777561B1 (en) 2004-08-17
US20050032789A1 (en) 2005-02-10
DE69920224T2 (de) 2005-10-13
EP1089965B1 (de) 2004-09-15
CA2335528A1 (en) 1999-12-29
AU4814699A (en) 2000-01-10
EP1089965A1 (de) 2001-04-11
WO1999067204A1 (en) 1999-12-29
SE9802209D0 (sv) 1998-06-22
PT1089965E (pt) 2004-12-31
AR029302A1 (es) 2003-06-25
DE69920224D1 (de) 2004-10-21
ES2228066T3 (es) 2005-04-01

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