DE69918283D1 - Stabilisierte herpesvirusformulierung - Google Patents

Stabilisierte herpesvirusformulierung

Info

Publication number
DE69918283D1
DE69918283D1 DE69918283T DE69918283T DE69918283D1 DE 69918283 D1 DE69918283 D1 DE 69918283D1 DE 69918283 T DE69918283 T DE 69918283T DE 69918283 T DE69918283 T DE 69918283T DE 69918283 D1 DE69918283 D1 DE 69918283D1
Authority
DE
Germany
Prior art keywords
herpesvirus
stabilized
virus
formulation
aminoacids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69918283T
Other languages
English (en)
Other versions
DE69918283T2 (de
Inventor
Alison Varley
Thomas Loudon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cantab Pharmaceuticals Research Ltd
Original Assignee
Cantab Pharmaceuticals Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cantab Pharmaceuticals Research Ltd filed Critical Cantab Pharmaceuticals Research Ltd
Publication of DE69918283D1 publication Critical patent/DE69918283D1/de
Application granted granted Critical
Publication of DE69918283T2 publication Critical patent/DE69918283T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE1999618283 1998-04-24 1999-04-26 Stabilisierte herpesvirusformulierung Expired - Fee Related DE69918283T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9808922A GB9808922D0 (en) 1998-04-24 1998-04-24 Virus preparations
GB9808922 1998-04-24
PCT/GB1999/001295 WO1999055348A2 (en) 1998-04-24 1999-04-26 Stabilised virus preparation

Publications (2)

Publication Number Publication Date
DE69918283D1 true DE69918283D1 (de) 2004-07-29
DE69918283T2 DE69918283T2 (de) 2005-07-21

Family

ID=10831020

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1999618283 Expired - Fee Related DE69918283T2 (de) 1998-04-24 1999-04-26 Stabilisierte herpesvirusformulierung

Country Status (12)

Country Link
US (1) US6258362B1 (de)
EP (1) EP1071438B1 (de)
JP (1) JP2002512970A (de)
AT (1) ATE269712T1 (de)
AU (1) AU3718299A (de)
CA (1) CA2329000C (de)
DE (1) DE69918283T2 (de)
DK (1) DK1071438T3 (de)
ES (1) ES2224646T3 (de)
GB (1) GB9808922D0 (de)
PT (1) PT1071438E (de)
WO (1) WO1999055348A2 (de)

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CA2467365C (en) * 2001-12-10 2012-11-20 Bavarian Nordic A/S Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions
AU2008201215B2 (en) * 2001-12-10 2010-11-18 Bavarian Nordic A/S Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions
ITMI20021040A1 (it) * 2002-05-16 2003-11-17 Novuspharma Spa Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
US7592171B2 (en) * 2003-02-20 2009-09-22 Centro Nacional De Investigaciones Cientificas (Cnic) Vibrio cholerae with improved biological safety features in freeze dried form
EP1708747A2 (de) * 2004-01-15 2006-10-11 Intervet International BV Stabilisatoren nichttierischen ursprungs und herstellungsverfahren dafür
CA2571261C (en) * 2004-06-29 2018-08-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Safer attenuated virus vaccines with missing or diminished latency of infection
KR101400379B1 (ko) * 2004-11-05 2014-05-28 웰스테트 바이올로직스 코포레이션 안정하고 여과 가능한 외피보유 바이러스 조성물
US20060141483A1 (en) * 2004-12-23 2006-06-29 Calton Gary J Stabilization of viral compositions
US20070031450A1 (en) * 2005-08-04 2007-02-08 Wyeth Stabilizers for veterinary vaccines
WO2007079147A2 (en) 2005-12-28 2007-07-12 Advanced Bionutrition Corporation A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
US8968721B2 (en) 2005-12-28 2015-03-03 Advanced Bionutrition Corporation Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
WO2008079539A2 (en) 2006-11-09 2008-07-03 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Recombinant herpesvirus with diminished latency and methods of using same
EP2117354B1 (de) 2006-12-18 2018-08-08 Advanced BioNutrition Corp. Trockenes nahrungsmittel mit lebendem probiotikum
US20080294361A1 (en) * 2007-05-24 2008-11-27 Popp Shane M Intelligent execution system for the monitoring and execution of vaccine manufacturing
US20110262943A1 (en) * 2008-10-17 2011-10-27 Tokyo University Of Marine Science And Technology Reagent kit for measuring freshness
WO2010111565A2 (en) 2009-03-27 2010-09-30 Advanced Bionutrition Corporation Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish
EP2435554B1 (de) 2009-05-26 2017-07-26 Advanced Bionutrition Corporation Stabile trockenpulverzusammensetzung mit biologisch aktiven mikroorganismen und/oder bioaktiven materialien sowie herstellungsverfahren dafür
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
PL2529004T3 (pl) 2010-01-28 2017-12-29 Advanced Bionutrition Corporation Sucha szklista kompozycja zawierająca bioaktywny materiał
AR082682A1 (es) 2010-08-13 2012-12-26 Advanced Bionutrition Corp Composicion estabilizadora de almacenamiento en seco para materiales biologicos
CN101972474B (zh) * 2010-11-11 2012-06-27 长春祈健生物制品有限公司 冻干带状疱疹减毒活疫苗及制备方法
EP2646051A4 (de) 2010-12-02 2014-05-28 Oncolytics Biotech Inc Flüssige virale formulierungen
MX349294B (es) 2010-12-02 2017-07-21 Oncolytics Biotech Inc Formulaciones virales liofilizadas.
EP3246400B1 (de) 2012-01-09 2019-10-23 Sanofi Pasteur Biologics, LLC Aufreinigung von herpesvirus
EP2852662B1 (de) * 2012-05-21 2020-09-16 Sanofi Pasteur Limited Herpesviruszusammensetzungen und zugehörige verfahren
FR3024780B1 (fr) * 2014-08-07 2018-11-30 Bertin Pharma Reactif pret a l'emploi
US12558395B2 (en) 2015-07-29 2026-02-24 Advanced Bionutrition Corp. Stable dry probiotic compositions for special dietary uses
MY194231A (en) 2015-07-29 2022-11-23 Advanced Bionutrition Corp Stable dry probiotic compositions for special dietary uses
GB201701239D0 (en) * 2017-01-25 2017-03-08 Glaxosmithkline Biologicals Sa Novel formulation
US20220193222A1 (en) * 2018-11-30 2022-06-23 Vaccine Stabilization Institute Viral formulations containing amino acids
MX2021007639A (es) 2018-12-27 2021-08-11 Amgen Inc Formulaciones de virus liofilizadas.
CN116270500B (zh) * 2021-12-30 2025-05-06 安徽贝金基因科技有限公司 一种高稳定性的溶瘤病毒组合物及其制备方法和其应用

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Also Published As

Publication number Publication date
ES2224646T3 (es) 2005-03-01
JP2002512970A (ja) 2002-05-08
WO1999055348A2 (en) 1999-11-04
ATE269712T1 (de) 2004-07-15
US6258362B1 (en) 2001-07-10
WO1999055348A3 (en) 1999-12-16
PT1071438E (pt) 2004-11-30
DE69918283T2 (de) 2005-07-21
EP1071438B1 (de) 2004-06-23
CA2329000C (en) 2010-03-23
EP1071438A2 (de) 2001-01-31
AU3718299A (en) 1999-11-16
CA2329000A1 (en) 1999-11-04
DK1071438T3 (da) 2004-10-25
GB9808922D0 (en) 1998-06-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee