ATE269712T1 - Stabilisierte herpesvirusformulierung - Google Patents
Stabilisierte herpesvirusformulierungInfo
- Publication number
- ATE269712T1 ATE269712T1 AT99919380T AT99919380T ATE269712T1 AT E269712 T1 ATE269712 T1 AT E269712T1 AT 99919380 T AT99919380 T AT 99919380T AT 99919380 T AT99919380 T AT 99919380T AT E269712 T1 ATE269712 T1 AT E269712T1
- Authority
- AT
- Austria
- Prior art keywords
- stabilized
- herpes virus
- virus
- virus formulation
- aminoacids
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9808922A GB9808922D0 (en) | 1998-04-24 | 1998-04-24 | Virus preparations |
PCT/GB1999/001295 WO1999055348A2 (en) | 1998-04-24 | 1999-04-26 | Stabilised virus preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE269712T1 true ATE269712T1 (de) | 2004-07-15 |
Family
ID=10831020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99919380T ATE269712T1 (de) | 1998-04-24 | 1999-04-26 | Stabilisierte herpesvirusformulierung |
Country Status (12)
Country | Link |
---|---|
US (1) | US6258362B1 (de) |
EP (1) | EP1071438B1 (de) |
JP (1) | JP2002512970A (de) |
AT (1) | ATE269712T1 (de) |
AU (1) | AU3718299A (de) |
CA (1) | CA2329000C (de) |
DE (1) | DE69918283T2 (de) |
DK (1) | DK1071438T3 (de) |
ES (1) | ES2224646T3 (de) |
GB (1) | GB9808922D0 (de) |
PT (1) | PT1071438E (de) |
WO (1) | WO1999055348A2 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19803453A1 (de) * | 1998-01-30 | 1999-08-12 | Boehringer Ingelheim Int | Vakzine |
CA2417274A1 (en) * | 2000-07-31 | 2002-02-07 | Aventis Pasteur Limited | Respiratory syncytial virus vaccines |
US7101693B2 (en) | 2001-09-07 | 2006-09-05 | Brigham Young University | Plasticized hydrophilic glasses for improved stabilization of biological agents |
AU2008201215B2 (en) * | 2001-12-10 | 2010-11-18 | Bavarian Nordic A/S | Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions |
HUP0402179A3 (en) * | 2001-12-10 | 2012-09-28 | Bavarian Nordic As | Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions |
ITMI20021040A1 (it) * | 2002-05-16 | 2003-11-17 | Novuspharma Spa | Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale |
WO2004073736A1 (es) * | 2003-02-20 | 2004-09-02 | Centro Nacional De Investigaciones Cientificas (Cnic) | Cepas atenuadas de vibrio cholerae y vacunas liofilizadas que las contienen |
US7435422B2 (en) | 2004-01-15 | 2008-10-14 | Intervet International B.V. | Non-animal origin stabilizers and processes for producing the same |
US8916175B2 (en) * | 2004-06-29 | 2014-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Safer attenuated varicella-zoster virus vaccines with missing or diminished latency of infection |
AU2005304866B2 (en) | 2004-11-05 | 2010-04-01 | Wellstat Biologics Corporation | Stable and filterable enveloped virus formulations |
US20060141483A1 (en) * | 2004-12-23 | 2006-06-29 | Calton Gary J | Stabilization of viral compositions |
BRPI0614601A2 (pt) * | 2005-08-04 | 2012-01-31 | Wyeth Corp | formulação de vacina animal; componente estabilizador; vacina animal; processo de preparação de uma formulação de vacina animal; estabilizador de vacina; e componente estabilizador de vacina |
US8097245B2 (en) | 2005-12-28 | 2012-01-17 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
WO2008079539A2 (en) | 2006-11-09 | 2008-07-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Recombinant herpesvirus with diminished latency and methods of using same |
CA2673120C (en) | 2006-12-18 | 2012-08-07 | Advanced Bionutrition Corporation | A dry food product containing live probiotic |
US20080294361A1 (en) * | 2007-05-24 | 2008-11-27 | Popp Shane M | Intelligent execution system for the monitoring and execution of vaccine manufacturing |
WO2010044365A1 (ja) * | 2008-10-17 | 2010-04-22 | 国立大学法人東京海洋大学 | 鮮度測定用試薬キット |
WO2010111565A2 (en) | 2009-03-27 | 2010-09-30 | Advanced Bionutrition Corporation | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
PL2435554T3 (pl) * | 2009-05-26 | 2018-01-31 | Advanced Bionutrition Corp | Stabilna kompozycja suchego proszku zawierająca biologicznie aktywne mikroorganizmy i/lub materiały bioaktywne i sposoby jej wykonania |
AR080073A1 (es) | 2010-01-28 | 2012-03-14 | Advanced Bionutrition Corp | Composicion vitrea seca que comprende un material bioactivo |
US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
BR112013003244B1 (pt) | 2010-08-13 | 2018-07-17 | Advanced Bionutrition Corp | composição seca estabilizante para material biológico, seu método de preparação, e formulação de carreamento oral |
CN101972474B (zh) * | 2010-11-11 | 2012-06-27 | 长春祈健生物制品有限公司 | 冻干带状疱疹减毒活疫苗及制备方法 |
MX349294B (es) | 2010-12-02 | 2017-07-21 | Oncolytics Biotech Inc | Formulaciones virales liofilizadas. |
CN103347535B (zh) | 2010-12-02 | 2015-11-25 | 昂科利蒂克斯生物科技公司 | 液体病毒制剂 |
EP2802649B1 (de) | 2012-01-09 | 2017-08-09 | Sanofi Pasteur Biologics, LLC | Aufreinigung von herpesvirus |
WO2013177172A2 (en) | 2012-05-21 | 2013-11-28 | Sanofi Pasteur Limited | Herpesvirus compositions and related methods |
FR3024780B1 (fr) * | 2014-08-07 | 2018-11-30 | Bertin Pharma | Reactif pret a l'emploi |
JP6889699B2 (ja) | 2015-07-29 | 2021-06-18 | アドバンスド バイオニュートリション コープ. | 特定栄養用途のための安定乾燥プロバイオティクス組成物 |
GB201701239D0 (en) * | 2017-01-25 | 2017-03-08 | Glaxosmithkline Biologicals Sa | Novel formulation |
WO2020113197A1 (en) * | 2018-11-30 | 2020-06-04 | Vaccine Stabilization Institute | Viral formulations containing amino acids |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE209738C (de) | ||||
GB960850A (en) * | 1961-09-08 | 1964-06-17 | Wellcome Found | Measles virus vaccine |
JPS4848621A (de) * | 1971-10-20 | 1973-07-10 | ||
JPS4868730A (de) * | 1971-12-21 | 1973-09-19 | ||
US3915794A (en) * | 1973-02-09 | 1975-10-28 | Rit Rech Ind Therapeut | Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them |
JPS5648488B2 (de) * | 1973-06-06 | 1981-11-16 | ||
JPS5341202B2 (de) * | 1974-03-12 | 1978-11-01 | ||
US4147772A (en) * | 1976-02-03 | 1979-04-03 | Merck & Co., Inc. | Vaccine stabilizer |
AU532186B2 (en) * | 1978-07-21 | 1983-09-22 | Merck & Co., Inc. | Herpes virus vaccine |
PT71926B (en) * | 1979-10-29 | 1982-03-31 | Merck & Co Inc | Process for preparing a liquid vaccine comprising a stabilizer |
US4338335A (en) * | 1980-02-05 | 1982-07-06 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
EP0048194A3 (de) * | 1980-08-28 | 1982-09-01 | Merck & Co. Inc. | Verfahren zur Lyophilisierung |
FR2505657A1 (fr) * | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
HU183765B (en) * | 1981-12-23 | 1984-05-28 | Phylaxia Oltoanyagtermeloe | Process for producing lyophilized vaccine against duck hepatitis |
DK331087A (da) | 1986-06-30 | 1987-12-31 | Smith Kline Rit | Stabilisator for levende vaccine |
JPS63230851A (ja) * | 1987-03-20 | 1988-09-27 | Sumitomo Metal Ind Ltd | 耐食性に優れた油井管用低合金鋼 |
IE61575B1 (en) | 1987-05-04 | 1994-11-16 | Merck & Co Inc | A stable lyophilized live herpes virus vaccine |
US5024836A (en) * | 1987-05-04 | 1991-06-18 | Merck & Co., Inc. | Stable lyophilized live herpes virus vaccine |
JPS63307827A (ja) * | 1987-06-08 | 1988-12-15 | Kitasato Inst:The | 安定化された生ウイルスワクチンおよびその製造法 |
JP2779447B2 (ja) * | 1988-03-20 | 1998-07-23 | 財団法人阪大微生物病研究会 | 弱毒マレック病ウイルス・ベクターを用いる組換え遺伝子作成法、及び該ウイルスの組換え体 |
DD299213A7 (de) * | 1988-05-04 | 1992-04-09 | Saechsische Landesgewerbefoerderungsgesellschaft M.B.H.,De | Verfahren zur stabilisierung eines lebendvirusimpfstoffes gegen temperatureinwirkung |
FR2633518B1 (fr) | 1988-06-30 | 1991-03-22 | Merieux Inst | Procede de stabilisation des vaccins et associations de vaccins a virus attenues conserves sous forme lyophilisee, et compositions obtenues |
JP3895366B2 (ja) | 1990-09-25 | 2007-03-22 | キャンタブ ファーマシューティカルズ リサーチ リミティド | ウィルス ワクチン |
US5665362A (en) * | 1990-09-25 | 1997-09-09 | Cantab Pharmaceuticals Research Limited | Viral vaccines |
US5837261A (en) * | 1990-09-25 | 1998-11-17 | Cantab Pharmaceuticals Research Limited | Viral vaccines |
PT713397E (pt) | 1992-03-24 | 2003-04-30 | United Cancer Res Inst | Vacina que contem virus vivos |
JPH06234659A (ja) | 1992-05-05 | 1994-08-23 | Handai Biseibutsubiyou Kenkyukai | 安定化生ワクチン |
CZ289574B6 (cs) | 1992-06-04 | 2002-02-13 | Merck And Co., Inc. | Způsob výroby ľivé, atenuované vakcíny viru varicella zoster |
US5360736A (en) * | 1992-06-04 | 1994-11-01 | Merck & Co., Inc. | Process for attenuated varicella zoster virus vaccine production |
AU696336B2 (en) | 1993-03-19 | 1998-09-10 | Cantab Pharmaceuticals Research Limited | Defective mutant non-retroviral virus (e.g. HSV) as vaccine |
CA2158935A1 (en) | 1993-10-12 | 1995-04-20 | Chiron Viagene, Inc. | Methods for preserving recombinant viruses |
EP0872249A4 (de) | 1995-03-17 | 2001-10-24 | Hisamitsu Pharmaceutical Co | Gentransferpräparation |
JP2000507963A (ja) | 1996-12-20 | 2000-06-27 | メルク エンド カンパニー インコーポレーテッド | 凍結乾燥ワクチン用安定剤 |
-
1998
- 1998-04-24 GB GB9808922A patent/GB9808922D0/en not_active Ceased
-
1999
- 1999-04-26 AU AU37182/99A patent/AU3718299A/en not_active Abandoned
- 1999-04-26 ES ES99919380T patent/ES2224646T3/es not_active Expired - Lifetime
- 1999-04-26 PT PT99919380T patent/PT1071438E/pt unknown
- 1999-04-26 AT AT99919380T patent/ATE269712T1/de not_active IP Right Cessation
- 1999-04-26 DK DK99919380T patent/DK1071438T3/da active
- 1999-04-26 CA CA2329000A patent/CA2329000C/en not_active Expired - Fee Related
- 1999-04-26 US US09/300,073 patent/US6258362B1/en not_active Expired - Fee Related
- 1999-04-26 DE DE1999618283 patent/DE69918283T2/de not_active Expired - Fee Related
- 1999-04-26 EP EP99919380A patent/EP1071438B1/de not_active Expired - Lifetime
- 1999-04-26 JP JP2000545546A patent/JP2002512970A/ja active Pending
- 1999-04-26 WO PCT/GB1999/001295 patent/WO1999055348A2/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ES2224646T3 (es) | 2005-03-01 |
EP1071438B1 (de) | 2004-06-23 |
PT1071438E (pt) | 2004-11-30 |
EP1071438A2 (de) | 2001-01-31 |
JP2002512970A (ja) | 2002-05-08 |
GB9808922D0 (en) | 1998-06-24 |
DK1071438T3 (da) | 2004-10-25 |
WO1999055348A2 (en) | 1999-11-04 |
CA2329000A1 (en) | 1999-11-04 |
AU3718299A (en) | 1999-11-16 |
CA2329000C (en) | 2010-03-23 |
DE69918283D1 (de) | 2004-07-29 |
US6258362B1 (en) | 2001-07-10 |
WO1999055348A3 (en) | 1999-12-16 |
DE69918283T2 (de) | 2005-07-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE269712T1 (de) | Stabilisierte herpesvirusformulierung | |
IL124941A0 (en) | Formulations of nerve growth factor suitable for lyophilization | |
NZ337885A (en) | vaccine formulation of an antigen, a TH-1 inducing adjuvant and a sparingly water soluble amino acid | |
MX9604907A (es) | Vacuna de combinacion de virus para la enfermedad de newcastle. | |
TR200002930T2 (tr) | Kolaylaştırıcı kompozisyonlar | |
BRPI0107737B1 (pt) | vírus do herpes simplex 1 (hsv1), uso do hsv1, e, composição farmacêutica | |
AU1198697A (en) | Stabilizers for live vaccines | |
AU1271799A (en) | Methods for preventing and treating bacterial infections using cellulose ace tatephthalate or hydroxypropyl methylcellulose phthalate excipients | |
AU2497292A (en) | Flavivirus envelope proteins with increased immunogenicity for use in immunization against virus infection | |
NO985094D0 (no) | Polymerpulver som er redispergerbart i vandige l°sninger | |
AU4622693A (en) | Potentiation of immunogenic response | |
GR3030834T3 (en) | Herpes simplex virus vp16 vaccines | |
US20080241187A1 (en) | Stabilization of viral compositions | |
ES2056042T1 (es) | Copolimeros solubles en agua de acetato de vinilo y acido maleamico. uso como fluidizadores o reductores de agua de alto alcance para suspensiones acuosas. | |
AR026637A1 (es) | Virus atenuados e inocuos de la diarrea virica bovina para uso en vacas gestantes | |
UA84667C2 (ru) | Вакцина, направленная против инфекции, вызванной вирусом герпеса болезни марека | |
EP0692974A4 (de) | Multikomponentenimpfstoff aus clostridien, der saponin als adjuvans benutzt | |
HUP0001991A2 (hu) | Varicella Zoster vírus 63-as géntermékkel szembeni vakcinák | |
EP1144009A3 (de) | Hilfsstoffe zur verwendung in adeno-assoziiertes virus enthaltenden pharmazeutischen zubereitungen und damit hergestellte pharmazeutische zubereitungen | |
CA2116355A1 (en) | Infectious bovine rhinotracheitis virus mutants and vaccines | |
BR0012985A (pt) | Vacina, bactéria, uso da mesma, e composição farmacêutica e métodos de tratamento ou prevenção de doença mediada por hsv em um hospedeiro humano ou animal e de uma infecção viral da mucosa de um hospedeiro humano ou animal | |
AR009866A1 (es) | Formulacion inmunopotenciadora para uso vacunal | |
PT100460A (pt) | Partiiculas derivadas de virus de herpes e vacinas que as contem | |
DK0929315T3 (da) | Krydsbeskyttende equine herpesviruspræparater, deres fremstilling og anvendelse | |
林建安 et al. | Composition of HT-7 LHCD and its Protection Systems |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1071438 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |