DE69916643T2 - Verwendung von hyaluronsäure zur behandlung der bestrahlungs-blasenentzündung - Google Patents
Verwendung von hyaluronsäure zur behandlung der bestrahlungs-blasenentzündung Download PDFInfo
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- DE69916643T2 DE69916643T2 DE69916643T DE69916643T DE69916643T2 DE 69916643 T2 DE69916643 T2 DE 69916643T2 DE 69916643 T DE69916643 T DE 69916643T DE 69916643 T DE69916643 T DE 69916643T DE 69916643 T2 DE69916643 T2 DE 69916643T2
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- 229940049954 penicillin Drugs 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 229940039716 prothrombin Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 229960001516 silver nitrate Drugs 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- SNXUWJAFSLKIMF-UHFFFAOYSA-M sodium;hypochlorous acid;4-tetradecylbenzenesulfonate Chemical compound [Na+].ClO.CCCCCCCCCCCCCCC1=CC=C(S([O-])(=O)=O)C=C1 SNXUWJAFSLKIMF-UHFFFAOYSA-M 0.000 description 1
- 238000011301 standard therapy Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229960001196 thiotepa Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229960001082 trimethoprim Drugs 0.000 description 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
- 210000000626 ureter Anatomy 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 239000000083 urinary anti-infective agent Substances 0.000 description 1
- 208000010570 urinary bladder carcinoma Diseases 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000003741 urothelium Anatomy 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10518498P | 1998-10-22 | 1998-10-22 | |
| US105184P | 1998-10-22 | ||
| PCT/CA1999/000994 WO2000024387A2 (en) | 1998-10-22 | 1999-10-22 | A method for preventing, reducing, and treating radiation cystitis using hyaluronic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69916643D1 DE69916643D1 (de) | 2004-05-27 |
| DE69916643T2 true DE69916643T2 (de) | 2005-04-28 |
Family
ID=22304511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69916643T Expired - Lifetime DE69916643T2 (de) | 1998-10-22 | 1999-10-22 | Verwendung von hyaluronsäure zur behandlung der bestrahlungs-blasenentzündung |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6667296B1 (https=) |
| EP (1) | EP1124546B1 (https=) |
| JP (1) | JP4685242B2 (https=) |
| AT (1) | ATE264674T1 (https=) |
| AU (1) | AU761158B2 (https=) |
| CA (1) | CA2347110C (https=) |
| DE (1) | DE69916643T2 (https=) |
| DK (1) | DK1124546T3 (https=) |
| ES (1) | ES2219070T3 (https=) |
| NZ (1) | NZ511068A (https=) |
| PT (1) | PT1124546E (https=) |
| WO (1) | WO2000024387A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9906619D0 (en) † | 1999-03-23 | 1999-05-19 | Zeneca Resins Bv | Compositions |
| WO2005058235A2 (en) * | 2003-12-10 | 2005-06-30 | Keryx Biopharmaceuticals, Inc. | Methods using sulodexide for the treatment of bladder disease |
| JP2007233949A (ja) * | 2006-03-03 | 2007-09-13 | Kyoto Univ | 排尿管理システム |
| ITMI20061030A1 (it) | 2006-05-26 | 2007-11-27 | Altergon Sa | Nuova composizione comprendente glicosamminoglicani a viscosita' controllata e uso di tale composizione nella terapuia della cistite cronica |
| DE102006060953A1 (de) | 2006-12-12 | 2008-08-07 | Farco-Pharma Gmbh | Pharmazeutische Zubereitung für die Behandlung entzündlicher Erkrankungen des Urogenitaltraktes |
| HUP0900717A3 (en) * | 2009-11-18 | 2012-02-28 | Richter Gedeon Nyrt | Pharmaceutical composition for urological use containing zinc hyaluronate |
| US8383161B2 (en) | 2009-12-15 | 2013-02-26 | Incept, Llc | Radioopaque covalently crosslinked hydrogel particle implants |
| RU2557949C1 (ru) * | 2014-08-14 | 2015-07-27 | Общество с ограниченной ответственностью "КОЛЕТЕКС" | Способ лечения лучевого и интерстициального цистита |
| US20180055822A1 (en) * | 2015-03-13 | 2018-03-01 | Repoceuticals Aps | Melatonin for Preventing and Treating Radiation Cystitis |
| RU2676431C1 (ru) * | 2018-02-26 | 2018-12-28 | Федеральное государственное бюджетное учреждение "Российский научный центр радиологии и хирургических технологий имени академика А.М. Гранова" Министерства здравоохранения Российской Федерации (ФГБУ "РНЦРХТ им. ак. А.М. Гранова" Минздрава России) | Способ моделирования лучевого цистита |
| WO2019236453A1 (en) * | 2018-06-03 | 2019-12-12 | Glycomira Therapeutics, Inc. | Methods for preventing a serious health consequence and/or tissue damage after exposure to ionizing radiation and /or chemotherapy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5880108A (en) * | 1995-02-14 | 1999-03-09 | Bioniche, Inc. | Method for treating the internal urinary bladder and associated structures using hyaluronic acid |
| IN181358B (https=) * | 1995-02-14 | 1998-05-30 | Bioniche Inc | |
| CA2154103C (en) * | 1995-07-18 | 1998-02-24 | Samuel Simon Asculai | Treatment of mucous membrane disease, trauma or condition and for the relief of pain |
| WO1998029125A1 (fr) * | 1996-12-27 | 1998-07-09 | Seikagaku Corporation | Remedes contre des troubles de la vessie |
-
1999
- 1999-10-22 JP JP2000577997A patent/JP4685242B2/ja not_active Expired - Lifetime
- 1999-10-22 AT AT99952186T patent/ATE264674T1/de active
- 1999-10-22 DK DK99952186T patent/DK1124546T3/da active
- 1999-10-22 AU AU64558/99A patent/AU761158B2/en not_active Ceased
- 1999-10-22 US US09/830,063 patent/US6667296B1/en not_active Expired - Lifetime
- 1999-10-22 EP EP99952186A patent/EP1124546B1/en not_active Expired - Lifetime
- 1999-10-22 DE DE69916643T patent/DE69916643T2/de not_active Expired - Lifetime
- 1999-10-22 ES ES99952186T patent/ES2219070T3/es not_active Expired - Lifetime
- 1999-10-22 WO PCT/CA1999/000994 patent/WO2000024387A2/en not_active Ceased
- 1999-10-22 NZ NZ511068A patent/NZ511068A/en not_active IP Right Cessation
- 1999-10-22 PT PT99952186T patent/PT1124546E/pt unknown
- 1999-10-22 CA CA002347110A patent/CA2347110C/en not_active Expired - Lifetime
-
2003
- 2003-11-10 US US10/705,255 patent/US20040152662A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000024387A3 (en) | 2000-08-03 |
| CA2347110C (en) | 2008-08-26 |
| AU6455899A (en) | 2000-05-15 |
| DK1124546T3 (da) | 2004-08-09 |
| ATE264674T1 (de) | 2004-05-15 |
| CA2347110A1 (en) | 2000-05-04 |
| AU761158B2 (en) | 2003-05-29 |
| JP4685242B2 (ja) | 2011-05-18 |
| DE69916643D1 (de) | 2004-05-27 |
| EP1124546B1 (en) | 2004-04-21 |
| PT1124546E (pt) | 2004-08-31 |
| WO2000024387A2 (en) | 2000-05-04 |
| JP2002528410A (ja) | 2002-09-03 |
| US6667296B1 (en) | 2003-12-23 |
| US20040152662A1 (en) | 2004-08-05 |
| EP1124546A2 (en) | 2001-08-22 |
| ES2219070T3 (es) | 2004-11-16 |
| NZ511068A (en) | 2003-10-31 |
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| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: BIONICHE TEORANTA, GALWAY, IR |