DE69911210D1 - Verwendung von piperin und derivate davon zur behandlung von hautpigmentierungstörungen und hautkrebs - Google Patents

Verwendung von piperin und derivate davon zur behandlung von hautpigmentierungstörungen und hautkrebs

Info

Publication number
DE69911210D1
DE69911210D1 DE69911210T DE69911210T DE69911210D1 DE 69911210 D1 DE69911210 D1 DE 69911210D1 DE 69911210 T DE69911210 T DE 69911210T DE 69911210 T DE69911210 T DE 69911210T DE 69911210 D1 DE69911210 D1 DE 69911210D1
Authority
DE
Germany
Prior art keywords
derivatives
skin
piperin
pigmentation disorders
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69911210T
Other languages
English (en)
Other versions
DE69911210T2 (de
Inventor
Amala Raman
Zhixiu Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OREG
Original Assignee
BTG International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BTG International Ltd filed Critical BTG International Ltd
Application granted granted Critical
Publication of DE69911210D1 publication Critical patent/DE69911210D1/de
Publication of DE69911210T2 publication Critical patent/DE69911210T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69911210T 1998-07-13 1999-07-13 Verwendung von piperin und derivate davon zur behandlung von hautpigmentierungstörungen und hautkrebs Expired - Lifetime DE69911210T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9815177.2A GB9815177D0 (en) 1998-07-13 1998-07-13 Treatment of skin disorders
GB9815177 1998-07-13
PCT/GB1999/002256 WO2000002544A2 (en) 1998-07-13 1999-07-13 Use of piperine for treating skin pigmentation disorders

Publications (2)

Publication Number Publication Date
DE69911210D1 true DE69911210D1 (de) 2003-10-16
DE69911210T2 DE69911210T2 (de) 2004-07-01

Family

ID=10835429

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69911210T Expired - Lifetime DE69911210T2 (de) 1998-07-13 1999-07-13 Verwendung von piperin und derivate davon zur behandlung von hautpigmentierungstörungen und hautkrebs

Country Status (14)

Country Link
US (1) US6346539B1 (de)
EP (1) EP1094813B1 (de)
JP (1) JP2002520275A (de)
KR (1) KR20010071872A (de)
CN (1) CN1210029C (de)
AT (1) ATE249220T1 (de)
AU (1) AU757053B2 (de)
CA (2) CA2735844C (de)
DE (1) DE69911210T2 (de)
ES (1) ES2207252T3 (de)
GB (1) GB9815177D0 (de)
HK (1) HK1033264A1 (de)
WO (1) WO2000002544A2 (de)
ZA (1) ZA200004260B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6680391B2 (en) 1998-07-13 2004-01-20 Btg International Limited Treatment of skin conditions
GB2370989A (en) * 2001-01-16 2002-07-17 Btg Int Ltd Piperine analogues for the treatment of skin conditions
GB9815177D0 (en) 1998-07-13 1998-09-09 King S College London Treatment of skin disorders
JP4098985B2 (ja) * 2000-05-19 2008-06-11 サビンサ コーポレーション テトラヒドロピペリンならびにその類似体および誘導体を用いて栄養素および薬剤調製物の生体利用能を高める方法
US7057040B2 (en) * 2002-02-07 2006-06-06 Council Of Scientific And Industrial Research Substituted aryl alkenoic acid heterocyclic amides
CN1389462A (zh) * 2002-07-12 2003-01-08 复旦大学 大叶蒟素及其同系物，和在制备药物组合物中的应用
DK2548880T3 (en) * 2003-06-23 2019-04-08 Telomerase Activation Sciences Inc Composition for enhancing telomerase activity
US9248088B2 (en) * 2003-06-25 2016-02-02 Telomerase Activation Sciences, Inc. Compositions and methods for skin conditioning
WO2005044179A2 (en) * 2003-06-27 2005-05-19 Hong Kong University Of Science And Technology Formulations containing astragalus extracts and uses thereof
DE10335725A1 (de) * 2003-08-05 2005-03-03 Bayer Cropscience Gmbh Safener auf Basis aromatisch-aliphatischer Carbonsäuredarivate
JP4579564B2 (ja) * 2004-03-16 2010-11-10 花王株式会社 シワ改善剤
GB0600134D0 (en) * 2006-01-05 2006-02-15 Vernique Biotech Ltd Use of epoxidised molecules
KR100846125B1 (ko) 2007-03-30 2008-07-15 바이오스펙트럼 주식회사 피페린을 유효성분으로 포함하는 피부주름 개선용 조성물
EP2011495A1 (de) * 2007-07-03 2009-01-07 Sygnis Bioscience GmbH & Co. KG Verwendungen von Piperin und Derivaten daraus zur Behandlung neurologischer Leiden
CH698627B1 (de) 2007-08-16 2009-09-15 Alpinia Laudanum Inst Of Phytopharmaceutical Herstellung und Verwendung von Extrakten oder Extraktivstoffen aus Piper cubeba L. als wirksame Bestandteile in einem Medikament zur Behandlung von Krebserkrankungen.
EP2198887A4 (de) * 2007-10-19 2011-11-30 Univ Tokyo Therapeutikum für leukodermie und verfahren zur pigmentierungsbeschleunigung
US20090312373A1 (en) * 2008-03-11 2009-12-17 The General Hospital Corporation Methods for the treatment of cancer using piperlongumine and piperlongumine analogs
KR101035956B1 (ko) * 2008-09-05 2011-05-23 인하대학교 산학협력단 밀통화 추출물을 유효성분으로 함유하는 아토피성 피부 개선용 화장료 조성물
US20110200566A1 (en) * 2008-09-30 2011-08-18 Xiaowei Xu Compositions and Methods for the Treatment of Vitiligo
IL196695A (en) * 2009-01-25 2015-10-29 Secret Of Youth Ltd Preparations containing fruit and vegetable derivatives and their uses
PL2437606T3 (pl) 2009-05-18 2017-07-31 Telomerase Activation Sciences, Inc. Kompozycje i sposoby zwiększania aktywności telomerazy
JP5813436B2 (ja) * 2011-09-22 2015-11-17 日本メナード化粧品株式会社 色素脱失の予防又は改善剤のスクリーニング法とそのスクリーニング法によって見出された色素脱失の予防又は改善剤
KR101186500B1 (ko) * 2012-01-31 2012-09-27 연세대학교 산학협력단 신규한 피페린 유도체 및 그의 용도
JP2016540762A (ja) * 2013-12-02 2016-12-28 ステルス バイオセラピューティックス コープ 白斑の治療のための組成物及び方法
CN104297225B (zh) * 2014-09-29 2018-02-16 无限极（中国）有限公司 一种细胞内黑色素的快速检测与成像的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06336417A (ja) 1993-03-31 1994-12-06 Shiseido Co Ltd 紫外線吸収剤及びそれを配合した皮膚外用剤
EP0650728B1 (de) 1993-10-29 2002-02-27 Council of Scientific and Industrial Research Pharmazeutische Zusammensetzungen, die Piperine und Antituberkulose- oder Antilepramedikamenten enthalten
US5744161A (en) * 1995-02-24 1998-04-28 Sabinsa Corporation Use of piperine as a bioavailability enhancer
GB9815177D0 (en) 1998-07-13 1998-09-09 King S College London Treatment of skin disorders

Also Published As

Publication number Publication date
JP2002520275A (ja) 2002-07-09
US6346539B1 (en) 2002-02-12
WO2000002544A3 (en) 2000-05-04
DE69911210T2 (de) 2004-07-01
CA2735844C (en) 2013-10-01
CA2337205A1 (en) 2000-01-20
CA2735844A1 (en) 2000-01-20
ZA200004260B (en) 2001-07-25
AU757053B2 (en) 2003-01-30
AU4920999A (en) 2000-02-01
HK1033264A1 (en) 2001-08-24
EP1094813B1 (de) 2003-09-10
CA2337205C (en) 2011-06-14
EP1094813A2 (de) 2001-05-02
WO2000002544A2 (en) 2000-01-20
ATE249220T1 (de) 2003-09-15
KR20010071872A (ko) 2001-07-31
CN1210029C (zh) 2005-07-13
CN1330545A (zh) 2002-01-09
ES2207252T3 (es) 2004-05-16
GB9815177D0 (en) 1998-09-09

Similar Documents

Publication Publication Date Title
ATE249220T1 (de) Verwendung von piperin und derivate davon zur behandlung von hautpigmentierungstörungen und hautkrebs
DE69921156D1 (de) Verwendung von 5ht-6 antagonisten zur behandlung adhd
DE60225169D1 (de) Photodynamische therapie zur behandlung von haarausfall
GB9903762D0 (en) Organic compounds
DE59903921D1 (de) Indolderivate und deren verwendung zur behandlung von malignen und anderen, auf pathologischen zellproliferationen beruhenden erkrankungen
DE60036169D1 (de) Methoden zur Behandlung der Hautpigmentierung
ATE495736T1 (de) Verwendung von derivaten der 2-oxothiazolidin-4- corbonsäure als prä-abschuppungsmittel
ATE258796T1 (de) Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen
NO20000752D0 (no) Metode for forhindring eller behandling av østrogen-avhengige sykdommer og forstyrrelser
ATE415962T1 (de) Verwendung von asiatsäure oder asiaticosid zur behandlung von krebs
DE60023816D1 (de) Verwendung von Lycopin in Zusammensetzungen zur Behandlung von Hautalterungs-Erscheinungen
ATE275400T1 (de) Verwendung von melatonin zur behandlung der androgenetischen und diffusen alopezie vom weiblichen typ
ATE374619T1 (de) Verwendung von neurofilamentproteinen zur behandlung von tumoren
ATE222119T1 (de) Verwendung von erythropoietin zur behandlung von multiple myelom
ATE366114T1 (de) Verwendung von anti-prolaktin agentien zur behandlung von krebs
ATE192923T1 (de) Verwendung von boswelliasäure zur behandlung von hirntumoren
ATE361071T1 (de) Verwendung von irbesartan zur vorbeugung oder behandlung pulmonaler hypertonie
DE59900286D1 (de) Verwendung von sphingosin-1-phosphat, sphingosin-1-phosphat-derivaten und/oder deren gemische zur behandlung von entzündlichen hautkrankheiten
DE69924284D1 (de) Verwendung von stimulatoren der neurotrophischen faktoren zur behandlung von neurodegenerativen ophthalmischen krankheiten
ATE261724T1 (de) Antikonvulsive derivate zur behandlung von posttraumatischen stresserkrankungen
HUP0300923A2 (hu) RAF és RAS protein kinázt tartalmazó készítmények és alkalmazásuk angiogenezis módosítására
DE602004016292D1 (de) Verwendung einer zusammensetzung mit vitamin k1-oxid oder einem derivat daraus zur behandlung und/oder vorbeugung von hautverletzungen bei säugern
ATE255892T1 (de) Verwendung von antikonvulsiven derivaten zur behandlung von bulimia nervosa
ATE482217T1 (de) Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen
DE60326348D1 (de) Makrozyclen zur behandlung von krebserkrankungen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OREG