DE69904701D1 - Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung - Google Patents

Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung

Info

Publication number
DE69904701D1
DE69904701D1 DE69904701T DE69904701T DE69904701D1 DE 69904701 D1 DE69904701 D1 DE 69904701D1 DE 69904701 T DE69904701 T DE 69904701T DE 69904701 T DE69904701 T DE 69904701T DE 69904701 D1 DE69904701 D1 DE 69904701D1
Authority
DE
Germany
Prior art keywords
polypeptide
physiologically active
preparation
sustained
active polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69904701T
Other languages
English (en)
Other versions
DE69904701T2 (de
Inventor
Yutaka Yamagata
Masafumi Misaki
Susumu Iwasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69904701D1 publication Critical patent/DE69904701D1/de
Application granted granted Critical
Publication of DE69904701T2 publication Critical patent/DE69904701T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DE69904701T 1998-03-20 1999-03-18 Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung Expired - Lifetime DE69904701T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7185398 1998-03-20
PCT/JP1999/001359 WO1999048519A1 (en) 1998-03-20 1999-03-18 Sustained-release preparation of physiologically active polypeptide and production thereof

Publications (2)

Publication Number Publication Date
DE69904701D1 true DE69904701D1 (de) 2003-02-06
DE69904701T2 DE69904701T2 (de) 2003-11-06

Family

ID=13472521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69904701T Expired - Lifetime DE69904701T2 (de) 1998-03-20 1999-03-18 Physiologisch aktives polypeptid enthaltende zubereitung mit verzögerter freisetzung und deren herstellung

Country Status (12)

Country Link
US (1) US6482864B1 (de)
EP (1) EP1061948B1 (de)
KR (1) KR20010042079A (de)
CN (1) CN1301172A (de)
AT (1) ATE230274T1 (de)
AU (1) AU744354B2 (de)
BR (1) BR9908936A (de)
CA (1) CA2324568A1 (de)
DE (1) DE69904701T2 (de)
DK (1) DK1061948T3 (de)
WO (1) WO1999048519A1 (de)
ZA (1) ZA200004597B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020063853A (ko) * 1999-09-17 2002-08-05 다케다 야쿠힌 고교 가부시키가이샤 단백질 분체의 제조 방법
CA2430934C (en) 2000-12-01 2011-06-21 Takeda Chemical Industries, Ltd. A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
EP1356809A4 (de) * 2000-12-28 2008-05-14 Takeda Pharmaceutical Retardzubereitungen
WO2002085399A1 (en) * 2001-04-20 2002-10-31 Takeda Chemical Industries, Ltd. Peptide-containing preparations
CA2448814A1 (en) * 2001-07-09 2003-01-23 Yamanouchi Pharmaceutical Co., Ltd. Composition for sustained release injections and production method thereof
US7202326B2 (en) * 2002-09-24 2007-04-10 Asahi Kasei Chemicals Corporation Glycolic acid copolymer and method for production thereof
CA2550695A1 (en) * 2003-12-16 2005-06-30 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R Glp-1 pharmaceutical compositions
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US20070004616A1 (en) * 2005-06-30 2007-01-04 Roland Cherif-Cheikh GLP-1 pharmaceutical compositions
MX2008001468A (es) * 2005-06-30 2008-04-07 Sod Conseils Rech Applic Composiciones farmaceuticas del peptido similar al glucagon-1.
WO2008143906A2 (en) * 2007-05-14 2008-11-27 Sustained Nano Systems Llc Hypercompressed particles for controlled release of ophthalmic medications
US8071119B2 (en) 2007-05-14 2011-12-06 Sustained Nano Systems Llc Controlled release implantable dispensing device and method
WO2010123563A2 (en) * 2009-04-23 2010-10-28 Sustained Nano Systems Llc Controlled release dispensing device
CN102145160A (zh) * 2011-03-07 2011-08-10 深圳市健元医药科技有限公司 一种lhrh拮抗剂注射用的缓释植入制剂
CN102580056B (zh) * 2011-12-16 2014-04-09 深圳市健元医药科技有限公司 一种含抗利尿成分的缓释注射剂及其制备方法
CN113695370B (zh) * 2021-08-30 2022-06-07 河北科技大学 一种天然低共熔离子液体及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962091A (en) 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
DE69005800T2 (de) 1989-05-01 1994-05-19 Alkermes Inc Verfahren zur herstellung von kleinen partikeln von biologisch aktiven molekülen.
FR2658432B1 (fr) 1990-02-22 1994-07-01 Medgenix Group Sa Microspheres pour la liberation controlee des substances hydrosolubles et procede de preparation.
US5478564A (en) 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
DE59309257D1 (de) 1992-10-26 1999-02-11 Sanol Arznei Schwarz Gmbh Verfahren zur herstellung von mikrokapseln
JPH08503950A (ja) 1992-12-02 1996-04-30 アルカーメス・コントロールド・セラピユーテイクス・インコーポレーテツド 徐放性成長ホルモン含有マイクロスフェア
US6087324A (en) * 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
NZ260909A (en) 1993-07-05 1995-04-27 Takeda Chemical Industries Ltd Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution
CA2224381A1 (en) * 1995-06-27 1997-01-16 Takeda Chemical Industries, Ltd. Method of producing sustained-release preparation
DE69717263T2 (de) 1996-03-28 2003-07-24 Takeda Chemical Industries, Ltd. Zubereitung mit verzögerter freisetzung und deren herstellung
KR20000057693A (ko) 1996-12-20 2000-09-25 다케다 야쿠힌 고교 가부시키가이샤 지효성 제제의 제조 방법
US6287587B2 (en) 1997-07-15 2001-09-11 Takeda Chemical Industries, Ltd. Process for producing sustained-release preparation by in-water drying

Also Published As

Publication number Publication date
CN1301172A (zh) 2001-06-27
AU2853399A (en) 1999-10-18
AU744354B2 (en) 2002-02-21
ZA200004597B (en) 2002-02-27
DK1061948T3 (da) 2003-03-31
ATE230274T1 (de) 2003-01-15
BR9908936A (pt) 2005-10-25
EP1061948A1 (de) 2000-12-27
US6482864B1 (en) 2002-11-19
CA2324568A1 (en) 1999-09-30
KR20010042079A (ko) 2001-05-25
DE69904701T2 (de) 2003-11-06
WO1999048519A1 (en) 1999-09-30
EP1061948B1 (de) 2003-01-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP