JPS55144887A - Preparation of physiologically active substance - Google Patents

Preparation of physiologically active substance

Info

Publication number
JPS55144887A
JPS55144887A JP5081979A JP5081979A JPS55144887A JP S55144887 A JPS55144887 A JP S55144887A JP 5081979 A JP5081979 A JP 5081979A JP 5081979 A JP5081979 A JP 5081979A JP S55144887 A JPS55144887 A JP S55144887A
Authority
JP
Japan
Prior art keywords
solution
plasminogen
preparation
active substance
physiologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5081979A
Other languages
Japanese (ja)
Other versions
JPS5650953B2 (en
Inventor
Sadayoshi Horiguchi
Akio Hasegawa
Mitsuru Shibukawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP5081979A priority Critical patent/JPS55144887A/en
Priority to DE3015699A priority patent/DE3015699C2/en
Priority to GB8013755A priority patent/GB2051075B/en
Priority to US06/143,680 priority patent/US4317882A/en
Priority to FR8009443A priority patent/FR2454809A1/en
Publication of JPS55144887A publication Critical patent/JPS55144887A/en
Publication of JPS5650953B2 publication Critical patent/JPS5650953B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Abstract

PURPOSE: To prepare a plasminogen activating factor (F) having a molecular weight of 45,000W68,000, by bringing cells having the ability to produce F derived from animals into contact with a solution for preparing plasminogen.
CONSTITUTION: A solution for preparing plasminogen (P) comprising carbon and nitrogen sources, and if necessary an inorganic salt or/and organic additive is kept at pH 6W9, and preferably at the oxygen concentration in the solution at 15% or more the saturation one, and then brought into contact with cells having the ability to produce the P activating factor (F) derived from animals, preferably men, at the residence time of 30 days or less, preferably 10 days or less. The solution is then post-treated at a pH of 4W12.
COPYRIGHT: (C)1980,JPO&Japio
JP5081979A 1979-04-26 1979-04-26 Preparation of physiologically active substance Granted JPS55144887A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP5081979A JPS55144887A (en) 1979-04-26 1979-04-26 Preparation of physiologically active substance
DE3015699A DE3015699C2 (en) 1979-04-26 1980-04-24 Manufacture of a plasminogen activator
GB8013755A GB2051075B (en) 1979-04-26 1980-04-25 Plasminogen activator
US06/143,680 US4317882A (en) 1979-04-26 1980-04-25 Production of plasminogen activator
FR8009443A FR2454809A1 (en) 1979-04-26 1980-04-25 PROCESS FOR PRODUCING A PLASMINOGEN ACTIVATOR

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5081979A JPS55144887A (en) 1979-04-26 1979-04-26 Preparation of physiologically active substance

Publications (2)

Publication Number Publication Date
JPS55144887A true JPS55144887A (en) 1980-11-12
JPS5650953B2 JPS5650953B2 (en) 1981-12-02

Family

ID=12869363

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5081979A Granted JPS55144887A (en) 1979-04-26 1979-04-26 Preparation of physiologically active substance

Country Status (1)

Country Link
JP (1) JPS55144887A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5865219A (en) * 1981-07-15 1983-04-18 イエダ・リサ−チ・アンド・デベロツプメント・コンパニ−・リミテツド Manufacture of plasminogen activator

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6069902U (en) * 1983-10-19 1985-05-17 松下電器産業株式会社 table type electric stove

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5865219A (en) * 1981-07-15 1983-04-18 イエダ・リサ−チ・アンド・デベロツプメント・コンパニ−・リミテツド Manufacture of plasminogen activator
JPH0137115B2 (en) * 1981-07-15 1989-08-04 Yeda Res & Dev

Also Published As

Publication number Publication date
JPS5650953B2 (en) 1981-12-02

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