DE69901840T2 - Neue salzform von pantoprazol - Google Patents

Neue salzform von pantoprazol

Info

Publication number
DE69901840T2
DE69901840T2 DE69901840T DE69901840T DE69901840T2 DE 69901840 T2 DE69901840 T2 DE 69901840T2 DE 69901840 T DE69901840 T DE 69901840T DE 69901840 T DE69901840 T DE 69901840T DE 69901840 T2 DE69901840 T2 DE 69901840T2
Authority
DE
Germany
Prior art keywords
salt
pantoprazol
new
pantoprazole
dihydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69901840T
Other languages
English (en)
Other versions
DE122005000049I1 (de
DE122005000049I2 (de
DE69901840D1 (de
Inventor
Bernhard Kohl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7881823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69901840(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Application granted granted Critical
Publication of DE69901840D1 publication Critical patent/DE69901840D1/de
Publication of DE69901840T2 publication Critical patent/DE69901840T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Drying Of Gases (AREA)
  • Detergent Compositions (AREA)
  • Manufacture And Refinement Of Metals (AREA)
DE69901840T 1998-08-18 1999-08-12 Neue salzform von pantoprazol Expired - Lifetime DE69901840T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843413A DE19843413C1 (de) 1998-08-18 1998-08-18 Neue Salzform von Pantoprazol
PCT/EP1999/005928 WO2000010995A1 (en) 1998-08-18 1999-08-12 Novel salt form of pantoprazole

Publications (2)

Publication Number Publication Date
DE69901840D1 DE69901840D1 (de) 2002-07-18
DE69901840T2 true DE69901840T2 (de) 2003-05-22

Family

ID=7881823

Family Applications (3)

Application Number Title Priority Date Filing Date
DE19843413A Expired - Fee Related DE19843413C1 (de) 1998-08-18 1998-08-18 Neue Salzform von Pantoprazol
DE69901840T Expired - Lifetime DE69901840T2 (de) 1998-08-18 1999-08-12 Neue salzform von pantoprazol
DE1999601840 Active DE122005000049I2 (de) 1998-08-18 1999-08-12 Neue Salzform von Pantoprazol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19843413A Expired - Fee Related DE19843413C1 (de) 1998-08-18 1998-08-18 Neue Salzform von Pantoprazol

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1999601840 Active DE122005000049I2 (de) 1998-08-18 1999-08-12 Neue Salzform von Pantoprazol

Country Status (33)

Country Link
US (2) US6410569B1 (de)
EP (1) EP1105386B1 (de)
JP (1) JP2002523411A (de)
KR (1) KR100657835B1 (de)
CN (1) CN1146558C (de)
AT (1) ATE219074T1 (de)
AU (1) AU761715B2 (de)
BG (1) BG65255B1 (de)
BR (1) BR9914288A (de)
CA (1) CA2341031C (de)
CZ (1) CZ293734B6 (de)
DE (3) DE19843413C1 (de)
DK (1) DK1105386T3 (de)
EA (1) EA004431B1 (de)
EE (1) EE04278B1 (de)
ES (1) ES2178896T3 (de)
HK (1) HK1037616A1 (de)
HR (1) HRP20010117B1 (de)
HU (1) HU226618B1 (de)
IL (3) IL141328A0 (de)
ME (1) ME00562A (de)
MX (1) MXPA01001758A (de)
NO (1) NO319782B1 (de)
NZ (1) NZ509761A (de)
PL (1) PL198801B1 (de)
PT (1) PT1105386E (de)
RS (1) RS50071B (de)
SI (1) SI1105386T1 (de)
SK (1) SK285105B6 (de)
TR (1) TR200100287T2 (de)
UA (1) UA58605C2 (de)
WO (1) WO2000010995A1 (de)
ZA (1) ZA200100934B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19843413C1 (de) * 1998-08-18 2000-03-30 Byk Gulden Lomberg Chem Fab Neue Salzform von Pantoprazol
MY137726A (en) 2000-11-22 2009-03-31 Nycomed Gmbh Freeze-dried pantoprazole preparation and pantoprazole injection
TW200410955A (en) * 2002-07-29 2004-07-01 Altana Pharma Ag Novel salt of (S)-PANTOPRAZOLE
DE10234617B4 (de) * 2002-07-29 2013-04-04 Nycomed Gmbh Neues Salz von (S)-Pantoprazol
CA2510849A1 (en) * 2002-12-19 2004-07-08 Teva Pharmaceutical Industries Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
WO2004098599A2 (en) * 2003-05-06 2004-11-18 Altana Pharma Ag Proton pump inhibitors for the treatment of lower abdominal disorders
CL2004000983A1 (es) * 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
PE20050150A1 (es) * 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
EP1631284A2 (de) * 2003-05-19 2006-03-08 Pliva-Istrazivanje I Razvoj D.D.O. Festphasen-formen von 5-(difluoromethoxy)-2-((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-1h-benzimidazol (pantoprazol) natrium aqua komplexen
EP1615913A2 (de) * 2003-06-10 2006-01-18 Teva Pharmaceutical Industries Limited Verfahren zur herstellung von (pyridinyl)methyl]sulfinyl-substituierte benzimidazoles und neue chlorierte derivate von pantoprazole
WO2005012289A1 (en) * 2003-07-17 2005-02-10 Altana Pharma Ag Novel salt of (r) - pantoprazole
CN100457104C (zh) * 2003-07-23 2009-02-04 尼科梅德有限责任公司 质子泵抑制剂的碱性盐
ATE386522T1 (de) * 2003-07-23 2008-03-15 Nycomed Gmbh Alkalisalze von protonenpumpen-hemmern
US20080234326A1 (en) * 2004-01-28 2008-09-25 Altana Pharma Ag Novel Salts of Pantoprazole and (S) - Pantoprazole
WO2005074932A1 (en) * 2004-01-28 2005-08-18 Altana Pharma Ag The use of (s) - pantoprazole magnesium for the treatment of airway disorders
WO2005074898A2 (en) * 2004-01-28 2005-08-18 Altana Pharma Ag Composition comprising (s) pantoprazole and an antibiotic for treating helicobacter pylori
WO2005074930A1 (en) * 2004-01-28 2005-08-18 Altana Pharma Ag Pharmaceutical combinations of (s) -pantoprazole with nsaid or corticosteroids
WO2005074931A1 (en) * 2004-01-28 2005-08-18 Altana Pharma Ag Pharmaceutical combinations comprising (s) -pantoprazole
EP1716136A1 (de) * 2004-02-11 2006-11-02 Ulkar Kimya Sanayii Ve Ticaret A.S. Pyridin benzimidazol sulfoxide hoher reinheit
WO2005082888A1 (en) * 2004-03-01 2005-09-09 Milen Merkez Ilac Endustrisi A.S. Process for the preparation of magnesium salt of omeprazole
EP1746980B1 (de) * 2004-05-07 2011-11-02 Nycomed GmbH Neue pharmazeutische dosierform und herstellungsverfahren
WO2007041790A1 (en) * 2005-10-14 2007-04-19 Jon Pty Limited Salts of proton pump inhibitors and process for preparing same
WO2007146341A2 (en) 2006-06-12 2007-12-21 Teva Pharmaceutical Industries Ltd. Amorphous and crystalline forms of pantoprazole magnesium salt
US20080177076A1 (en) * 2006-11-06 2008-07-24 Lilach Hedvanti Processes for preparing substantially pure pantoprazole magnesium
WO2017114898A1 (en) * 2015-12-30 2017-07-06 Krka, Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of pantoprazole sodium sesquihydrate
EP3187494A1 (de) * 2015-12-30 2017-07-05 KRKA, tovarna zdravil, d.d., Novo mesto Verfahren zur herstellung von pantoprazole natrium sesquihydrat

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
IL75400A (en) 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
DE4018642C2 (de) 1990-06-11 1993-11-25 Byk Gulden Lomberg Chem Fab Neue Salzform des 5-Difluormethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl]-1H-benzimitazol-Natriumsalzes
YU48263B (sh) * 1991-06-17 1997-09-30 Byk Gulden Lomberg Chemische Fabrik Gmbh. Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola
SE9302396D0 (sv) 1993-07-09 1993-07-09 Ab Astra A novel compound form
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
DE19843413C1 (de) * 1998-08-18 2000-03-30 Byk Gulden Lomberg Chem Fab Neue Salzform von Pantoprazol

Also Published As

Publication number Publication date
NZ509761A (en) 2003-08-29
ES2178896T3 (es) 2003-01-01
US20020188008A1 (en) 2002-12-12
DE122005000049I1 (de) 2006-12-28
DE19843413C1 (de) 2000-03-30
SK285105B6 (sk) 2006-06-01
NO20010718L (no) 2001-02-12
AU761715B2 (en) 2003-06-05
NO20010718D0 (no) 2001-02-12
KR20010072487A (ko) 2001-07-31
HUP0103257A2 (hu) 2002-02-28
SK2362001A3 (en) 2001-09-11
DE122005000049I2 (de) 2007-03-29
ME00562B (me) 2011-12-20
DK1105386T3 (da) 2002-09-30
AU5515699A (en) 2000-03-14
CN1146558C (zh) 2004-04-21
CZ2001621A3 (cs) 2001-08-15
RS50071B (sr) 2009-01-22
IL141157A (en) 2007-06-17
CZ293734B6 (cs) 2004-07-14
EE04278B1 (et) 2004-04-15
YU11301A (sh) 2003-12-31
US6410569B1 (en) 2002-06-25
NO319782B1 (no) 2005-09-12
EA200100208A1 (ru) 2001-08-27
SI1105386T1 (en) 2002-12-31
PL345993A1 (en) 2002-01-14
US6686379B2 (en) 2004-02-03
HUP0103257A3 (en) 2003-01-28
CA2341031C (en) 2006-04-04
EP1105386B1 (de) 2002-06-12
EA004431B1 (ru) 2004-04-29
PL198801B1 (pl) 2008-07-31
TR200100287T2 (tr) 2001-07-23
EE200100054A (et) 2002-06-17
HRP20010117B1 (en) 2010-07-31
EP1105386A1 (de) 2001-06-13
HK1037616A1 (en) 2002-02-15
BR9914288A (pt) 2001-06-19
BG105173A (en) 2001-11-30
ME00562A (en) 2011-12-20
CN1318065A (zh) 2001-10-17
HU226618B1 (en) 2009-04-28
ZA200100934B (en) 2002-03-04
HRP20010117A2 (en) 2002-02-28
ATE219074T1 (de) 2002-06-15
MXPA01001758A (es) 2002-04-17
BG65255B1 (bg) 2007-10-31
CA2341031A1 (en) 2000-03-02
DE69901840D1 (de) 2002-07-18
JP2002523411A (ja) 2002-07-30
IL141328A0 (en) 2002-03-10
UA58605C2 (uk) 2003-08-15
PT1105386E (pt) 2002-11-29
IL141157A0 (en) 2002-02-10
KR100657835B1 (ko) 2006-12-15
WO2000010995A1 (en) 2000-03-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ALTANA PHARMA AG, 78467 KONSTANZ, DE

8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
V448 Application of spc

Free format text: PRODUCT NAME: PANTOPRAZOL-HEMIMAGNESIUM 1 H2O; REGISTRATION NO/DATE: 61695.00.00, 61696.00.00, 61697.00.00, 61698.00.00; 20050510

Spc suppl protection certif: 12 2005 000 049

Filing date: 20051102

V484 Delivery of the decision of grant

Free format text: PRODUCT NAME: PANTOPRAZOL-HEMIMAGNESIUM 1 H2O; REGISTRATION NO/DATE: 61695.00.00, 61696.00.00, 61697.00.00, 61698.00.00; 20050510

Spc suppl protection certif: 12 2005 000 049

Filing date: 20051102

V457 Spc granted

Free format text: PRODUCT NAME: PANTOPRAZOL-HEMIMAGNESIUM 1 H2O; REGISTRATION NO/DATE: 61695.00.00, 61696.00.00, 61697.00.00, 61698.00.00; 20050510

Spc suppl protection certif: 12 2005 000 049

Filing date: 20051102

8327 Change in the person/name/address of the patent owner

Owner name: NYCOMED GMBH, 78467 KONSTANZ, DE