DE69840851D1 - Kleine peptide und methoden zur behandlung von asthma und entzündungen - Google Patents

Kleine peptide und methoden zur behandlung von asthma und entzündungen

Info

Publication number
DE69840851D1
DE69840851D1 DE69840851T DE69840851T DE69840851D1 DE 69840851 D1 DE69840851 D1 DE 69840851D1 DE 69840851 T DE69840851 T DE 69840851T DE 69840851 T DE69840851 T DE 69840851T DE 69840851 D1 DE69840851 D1 DE 69840851D1
Authority
DE
Germany
Prior art keywords
phe
methods
tyr
asthma
ignition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840851T
Other languages
English (en)
Inventor
John C Houck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mowycal Lending LLC
Original Assignee
Mowycal Lending LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mowycal Lending LLC filed Critical Mowycal Lending LLC
Application granted granted Critical
Publication of DE69840851D1 publication Critical patent/DE69840851D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69840851T 1997-11-13 1998-07-07 Kleine peptide und methoden zur behandlung von asthma und entzündungen Expired - Lifetime DE69840851D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6533697P 1997-11-13 1997-11-13
PCT/US1998/014103 WO1999025372A1 (en) 1997-11-13 1998-07-07 Small peptides and methods for treatment of asthma and inflammation

Publications (1)

Publication Number Publication Date
DE69840851D1 true DE69840851D1 (de) 2009-07-09

Family

ID=22062006

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840851T Expired - Lifetime DE69840851D1 (de) 1997-11-13 1998-07-07 Kleine peptide und methoden zur behandlung von asthma und entzündungen

Country Status (12)

Country Link
US (17) US6391856B1 (de)
EP (1) EP1037651B1 (de)
JP (1) JP2002516820A (de)
KR (1) KR100629546B1 (de)
CN (1) CN1282253A (de)
AT (1) ATE432078T1 (de)
AU (1) AU8477998A (de)
BR (1) BR9815288A (de)
CA (1) CA2309639C (de)
DE (1) DE69840851D1 (de)
ES (1) ES2326500T3 (de)
WO (1) WO1999025372A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002516820A (ja) * 1997-11-13 2002-06-11 ヒスタテク・エルエルシー 低分子量ペプチド及び喘息及び炎症の治療方法
KR100596136B1 (ko) * 1998-12-03 2006-07-05 히스타테크, 엘엘씨 소형 펩타이드 및 천식 및 염증을 치료하기 위한 방법
PL203758B1 (pl) * 1999-03-22 2009-11-30 Mowycal Lending Llc Zastosowanie peptydu o aktywności przeciwko zwłóknieniu
WO2001005420A1 (en) * 1999-07-16 2001-01-25 Histatek, Llc Small peptides and methods for downregulation of ige
CA2715683A1 (en) * 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
CN100497374C (zh) * 1999-10-15 2009-06-10 莫维克借贷有限责任公司 与g蛋白激酶信号途径修饰剂形成的n-甲酰基肽受体复合物
EP1578252A4 (de) * 2002-12-30 2009-11-25 Yeda Res & Dev Verfahren zur auswertung der genetischen anfälligkeit und therapie für chronische entzündungskrankheiten
EP1587482A4 (de) * 2003-01-31 2010-08-25 Technion Res & Dev Foundation Entzündungshemmende zusammensetzungen und ihre verwendungen
CN1882344A (zh) 2003-11-18 2006-12-20 诺瓦提斯公司 Kit突变形式的抑制剂
EP1737475A4 (de) * 2004-03-19 2009-08-05 Xiu-Min Li Pflanzliche therapie zur behandlung von asthma
WO2006119154A1 (en) 2005-05-02 2006-11-09 Novartis Ag Use of pyrimidylamimobenzamide derivatives for the treatment of systematic mastocytosis
EP1954320A2 (de) * 2005-11-15 2008-08-13 Baxter International Inc. Zusammensetzungen mit lipoxygenase-hemmern und zyklodextrin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
NZ314680A (en) 1989-05-09 2000-08-25 Ortho Pharma Corp Treating localised infection or inflammation with a therapeutically conjugated chemotactic peptide
GB8919504D0 (en) * 1989-08-29 1989-10-11 Leo Pharm Prod Ltd Chemical compounds
US5776892A (en) 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
GB2292079B (en) * 1994-08-12 1998-07-15 Flexpharm Ltd Coated prednisolone preparation for the treatment of inflamatory bowel disease
JP2002516820A (ja) 1997-11-13 2002-06-11 ヒスタテク・エルエルシー 低分子量ペプチド及び喘息及び炎症の治療方法
KR100596136B1 (ko) 1998-12-03 2006-07-05 히스타테크, 엘엘씨 소형 펩타이드 및 천식 및 염증을 치료하기 위한 방법

Also Published As

Publication number Publication date
CA2309639A1 (en) 1999-05-27
US20080214472A1 (en) 2008-09-04
US20120058958A1 (en) 2012-03-08
US8809281B2 (en) 2014-08-19
ES2326500T3 (es) 2009-10-13
JP2002516820A (ja) 2002-06-11
US7994137B2 (en) 2011-08-09
US20080214476A1 (en) 2008-09-04
ATE432078T1 (de) 2009-06-15
EP1037651B1 (de) 2009-05-27
US20080214478A1 (en) 2008-09-04
BR9815288A (pt) 2001-02-13
US6462020B1 (en) 2002-10-08
EP1037651A4 (de) 2001-12-19
US20080214473A1 (en) 2008-09-04
US20030013658A1 (en) 2003-01-16
KR100629546B1 (ko) 2006-09-27
CN1282253A (zh) 2001-01-31
AU8477998A (en) 1999-06-07
US20030130200A1 (en) 2003-07-10
US20130274208A1 (en) 2013-10-17
US20120094938A1 (en) 2012-04-19
US20130252907A1 (en) 2013-09-26
US20140127245A1 (en) 2014-05-08
US20080214474A1 (en) 2008-09-04
CA2309639C (en) 2010-03-23
US20080187994A1 (en) 2008-08-07
EP1037651A1 (de) 2000-09-27
US8012934B2 (en) 2011-09-06
US8097589B2 (en) 2012-01-17
US20080214477A1 (en) 2008-09-04
KR20010032072A (ko) 2001-04-16
US6391856B1 (en) 2002-05-21
WO1999025372A1 (en) 1999-05-27
US20080214475A1 (en) 2008-09-04

Similar Documents

Publication Publication Date Title
DE69840851D1 (de) Kleine peptide und methoden zur behandlung von asthma und entzündungen
DE69533855D1 (de) UNTERBRECHUNG DER BINDUNG DER PROTEINE MDM2 UND p53 UND ENTSPRECHENDE THERAPEUTISCHE ANWENDUNG
EA200400632A1 (ru) Пептиды, эффективные в лечении опухолей и других заболеваний, требующих удаления или разрушения клеток
EP2327712A3 (de) Behandlung von Autoimmunkrankheiten mittels Copolymer 1 und ähnlichen Copolymeren und Peptiden
DE69326064D1 (de) Peptide des menschlichen Proteins P53 zum Gebrauch in menschlichen-zytotoxischen-T-Zell-Antwort-induzierenden Kompositionen sowie menschliche P53-Protein-spezifische T-Lymphocyten
EP0794797A4 (de) Methoden und zubehör zur immunisierung von wirtsorganismen durch verabreichung nackter polynucleotide , welche für antigene peptide codieren
ATE230417T1 (de) Peptid-immunogene zur schutzimpfung gegen und behandlung von allergien
ATE181835T1 (de) Wundbehandlung mittels biologisch aktiver peptide
EP0863913A4 (de) Methode zur erhölung der dichte eines antigens auf antigen-präsentierenden zellen
DE69533704D1 (de) Bradykinin-antagonist peptide mit n-substituierten glycinen
BR0209990A (pt) Peptìdeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de células
DE60140960D1 (de) Verwendung von serp-1 in kombination mit einem immunosuppressor zur behandlung von arthritis
ATE230609T1 (de) Verfahren zur behandlung von entzündungen und zusammensetzungen dafür
WO1993019178A3 (en) Peptides useful for inducing tolerance
DE68917837D1 (de) Peptid-Verbindungen.
DE69716460T2 (de) Wundheilung und behandlung von fibrose
ATE510008T1 (de) Entzündungshemmende peptide
ATE359296T1 (de) Pharmazeutische peptide formulierungen zur behandlung von staubmilben allergie
ATE218334T1 (de) Verwendung von gabapentin in der behandlung vonangst - und panikstörungen
BR9816097A (pt) Métodos para tratar uma reação alérgica em um mamìfero, inflamação cutânea em um mamìfero, artrite selecionada do grupo que consiste de osteoartrite, artrite psoriática, lupus, e espondilartrite, doença pulmonar de obstrução crÈnica em um paciente, doença de intestino inflamatória crÈnica em um paciente, para inibir a infiltração de eosinófilos em vias aéreas de um paciente, a liberação de mucosa em vias áreas de um paciente, para bloquear a ativação ige de um linfócito, para estabilizar a membrana da célula de um linfócito, e para inibir a migração de células-t
AU4712993A (en) New peptides, antibodies raised against peptides and means for blocking said antibodies, application as medicaments, pharmaceutical compositions and utilization methods
RU2136308C1 (ru) Стимулятор роста костно-мозговых клеток человека
EA200200169A1 (ru) МАЛЫЕ ПЕПТИДЫ И СПОСОБЫ ПОНИЖАЮЩЕЙ РЕГУЛЯЦИИ IgE
WO2001028582A3 (en) Therapeutic applications of flint polypeptides
HUP0202653A2 (hu) Autoimmun állapotok kezelése 1-típusú kopolimerrel és rokon kopolimerekkel

Legal Events

Date Code Title Description
8364 No opposition during term of opposition