DE69840277D1 - Dosierungsform eines Pulveragglomerates - Google Patents

Dosierungsform eines Pulveragglomerates

Info

Publication number
DE69840277D1
DE69840277D1 DE69840277T DE69840277T DE69840277D1 DE 69840277 D1 DE69840277 D1 DE 69840277D1 DE 69840277 T DE69840277 T DE 69840277T DE 69840277 T DE69840277 T DE 69840277T DE 69840277 D1 DE69840277 D1 DE 69840277D1
Authority
DE
Germany
Prior art keywords
dosage form
powder agglomerate
agglomerate
powder
dosage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840277T
Other languages
English (en)
Inventor
Tsong-Toh Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25232603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69840277(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE69840277D1 publication Critical patent/DE69840277D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE69840277T 1997-03-20 1998-03-16 Dosierungsform eines Pulveragglomerates Expired - Lifetime DE69840277D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82112997A 1997-03-20 1997-03-20

Publications (1)

Publication Number Publication Date
DE69840277D1 true DE69840277D1 (de) 2009-01-08

Family

ID=25232603

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69840277T Expired - Lifetime DE69840277D1 (de) 1997-03-20 1998-03-16 Dosierungsform eines Pulveragglomerates
DE69828155T Expired - Lifetime DE69828155T2 (de) 1997-03-20 1998-03-16 Herstellung von pulveragglomeraten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69828155T Expired - Lifetime DE69828155T2 (de) 1997-03-20 1998-03-16 Herstellung von pulveragglomeraten

Country Status (26)

Country Link
EP (3) EP1393721B1 (de)
JP (5) JP3901738B2 (de)
KR (1) KR100386055B1 (de)
CN (3) CN1149076C (de)
AR (1) AR011986A1 (de)
AT (2) ATE284677T1 (de)
AU (1) AU741783B2 (de)
CA (3) CA2706634C (de)
CL (1) CL2011000050A1 (de)
CZ (1) CZ295460B6 (de)
DE (2) DE69840277D1 (de)
DK (2) DK0969816T3 (de)
ES (2) ES2316681T3 (de)
HK (2) HK1021323A1 (de)
HU (2) HU226671B1 (de)
ID (1) ID24472A (de)
IL (1) IL131640A0 (de)
MY (1) MY120725A (de)
NO (1) NO328062B1 (de)
NZ (1) NZ337443A (de)
PL (3) PL208480B1 (de)
PT (2) PT969816E (de)
SK (1) SK284919B6 (de)
TW (1) TWI221778B (de)
WO (1) WO1998041193A1 (de)
ZA (1) ZA982254B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9723985D0 (en) 1997-11-14 1998-01-14 Zeneca Ltd Pharmaceutical compositions
SE9804000D0 (sv) 1998-11-23 1998-11-23 Astra Ab New composition of matter
SE9804001D0 (sv) 1998-11-23 1998-11-23 Astra Ab New process
AR022695A1 (es) * 1999-01-28 2002-09-04 Schering Corp PORTADOR SoLIDO PARTICULADO Y MÉTODO PARA PROVEER CONTROL DE LA PARTICULADA PARA LA DISTRIBUCIoN DE TAMANO DE PARTíCULAS Y DE CONTENIDO AMORFO CONVERTIBLE DURANTE SU PREPARACION
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
GB9903759D0 (en) * 1999-02-18 1999-04-14 Novartis Ag Organic compounds
GB9904919D0 (en) 1999-03-03 1999-04-28 Novartis Ag Organic compounds
CA2382216A1 (en) * 1999-08-20 2001-03-01 Xian Ming Zeng Method to produce powders for pulmonary or nasal administration
GB0009612D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic formulations
GB0009605D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medicaments
GB0009609D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic compositions
FI20002177A0 (fi) * 2000-10-02 2000-10-02 Orion Yhtymae Oyj Uusi yhdistelmä astman hoitoon
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
ITMI20012174A1 (it) * 2001-10-18 2003-04-18 Univ Parma Polvere per somministrazione nasale di farmaci
US7931022B2 (en) 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
EP1452179A1 (de) * 2003-02-27 2004-09-01 CHIESI FARMACEUTICI S.p.A. Neue Kombination von hochwirksamer langzeitiger Beta-2-Agonist und einem Corticosteroid
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
JP2007501194A (ja) * 2003-08-05 2007-01-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ステロイドとβ模倣薬を含む吸入用薬剤
EP1667687A1 (de) * 2003-09-26 2006-06-14 Schering Corporation Behandlung von lungenerkrankung
EP1686960A4 (de) * 2003-10-28 2007-03-07 Glaxo Group Ltd Inhalbierbare pharmazeutische formulierungen mit lactoseanhydrat und verabreichungsverfahren dafür
WO2005053651A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate compositions with improved stability
CN1889932A (zh) * 2003-12-04 2007-01-03 辉瑞产品公司 制备药用多颗粒的方法
SE528121C2 (sv) * 2004-03-29 2006-09-05 Mederio Ag Preparering av torrpulver för på förhand uppmätt DPI
IL168603A (en) * 2005-05-16 2011-05-31 Resdevco Res And Dev Co Pharmaceutical or cosmetic composition for the prevention and treatment of irritation of mucous cells or skin cells
DE102006030166A1 (de) * 2006-06-29 2008-01-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tempern
DE102006053375A1 (de) * 2006-11-10 2008-05-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mischung von Pulvern
TW201024034A (en) 2008-12-30 2010-07-01 Saint Gobain Abrasives Inc Bonded abrasive tool and method of forming
AU2010238641A1 (en) * 2009-04-24 2011-11-10 Merck Sharp & Dohme Corp. Agglomerate formulations useful in dry powder inhalers
EP2435023B1 (de) 2009-05-29 2016-07-06 Pearl Therapeutics, Inc. Zusammensetzung für die pulmonale freisetzung von muskarinischen antagonisten mit langzeitwirkung und adrenergischen beta-2-rezeptoragonisten mit langzeitwirkung sowie zugehörige verfahren und systeme
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
GB0918150D0 (en) * 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
WO2011131663A1 (en) * 2010-04-21 2011-10-27 Chiesi Farmaceutici S.P.A. "process for providing particles with reduced electrostatic charges"
AU2014228414B2 (en) 2013-03-15 2018-09-13 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials
JP6020489B2 (ja) 2014-02-27 2016-11-02 トヨタ自動車株式会社 昇圧コンバータ及びその制御方法
CN107106641B (zh) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 粉末制剂
JP7015549B2 (ja) * 2016-01-08 2022-02-03 セロン ファーマシューティカルズ， インク ７－アゾニアビシクロ［２．２．１］ヘプタン誘導体の乾燥粉末吸入器組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520247A (en) 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
GB8334494D0 (en) 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
DK0441740T3 (da) * 1990-01-29 1993-11-08 Ciba Geigy Ag Fremgangsmåde og apparat til dosering af et firkornet pulver
SE9101090D0 (sv) * 1991-04-11 1991-04-11 Astra Ab Process for conditioning of water-soluble substances
SE9302777D0 (sv) 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
PT613371E (pt) * 1991-12-18 2002-07-31 Astrazeneca Ab Nova combinacao de formoterol e budesonido
WO1994014492A2 (en) * 1992-12-18 1994-07-07 Schering Corporation Inhaler for powdered medications
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
ATE209903T1 (de) * 1993-10-01 2001-12-15 Astrazeneca Ab Verfahren i
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
PL321094A1 (en) * 1994-12-22 1997-11-24 Astra Ab Parathyroid hormone (pth) containing preparation administered by inhalation

Also Published As

Publication number Publication date
CA2282360A1 (en) 1998-09-24
CA2706634A1 (en) 1998-09-24
PL335742A1 (en) 2000-05-08
EP2036544B1 (de) 2016-12-28
HK1061359A1 (en) 2004-09-17
AU741783B2 (en) 2001-12-06
IL131640A0 (en) 2001-01-28
DE69828155D1 (de) 2005-01-20
JP2006152000A (ja) 2006-06-15
AU6537898A (en) 1998-10-12
CN1552310A (zh) 2004-12-08
HUP0002029A2 (hu) 2000-11-28
NO994519L (no) 1999-11-19
PL208480B1 (pl) 2011-05-31
PL192441B1 (pl) 2006-10-31
JP2000510478A (ja) 2000-08-15
SK284919B6 (sk) 2006-02-02
CN1257423A (zh) 2000-06-21
PL204480B1 (pl) 2010-01-29
CZ295460B6 (cs) 2005-08-17
AR011986A1 (es) 2000-09-13
ES2234102T3 (es) 2005-06-16
PT1393721E (pt) 2009-02-02
ID24472A (id) 2000-07-20
NO328062B1 (no) 2009-11-13
CA2282360C (en) 2004-11-09
DK1393721T3 (da) 2009-03-30
EP1393721B1 (de) 2008-11-26
CN100518718C (zh) 2009-07-29
JP5523240B2 (ja) 2014-06-18
KR20010005520A (ko) 2001-01-15
CN1903179A (zh) 2007-01-31
EP2036544A1 (de) 2009-03-18
ATE415149T1 (de) 2008-12-15
HUP0002029A3 (en) 2001-02-28
TWI221778B (en) 2004-10-11
EP0969816B1 (de) 2004-12-15
JP3901738B2 (ja) 2007-04-04
MY120725A (en) 2005-11-30
CA2481868C (en) 2010-06-15
HU226671B1 (en) 2009-06-29
JP2010275316A (ja) 2010-12-09
DE69828155T2 (de) 2005-12-22
JP2010248260A (ja) 2010-11-04
HU230274B1 (hu) 2015-11-30
EP1393721A1 (de) 2004-03-03
CN1149076C (zh) 2004-05-12
PT969816E (pt) 2005-04-29
CZ323399A3 (cs) 2000-02-16
HU0600845D0 (en) 2007-01-29
CN100548277C (zh) 2009-10-14
JP2014037446A (ja) 2014-02-27
CA2481868A1 (en) 1998-09-24
HK1021323A1 (en) 2000-06-09
WO1998041193A1 (en) 1998-09-24
ZA982254B (en) 1998-09-17
SK128099A3 (en) 2000-06-12
ES2316681T3 (es) 2009-04-16
KR100386055B1 (ko) 2003-06-09
EP0969816A1 (de) 2000-01-12
DK0969816T3 (da) 2005-03-14
ATE284677T1 (de) 2005-01-15
NZ337443A (en) 2001-04-27
CA2706634C (en) 2012-10-23
NO994519D0 (no) 1999-09-17
CL2011000050A1 (es) 2011-06-24

Similar Documents

Publication Publication Date Title
DE69840277D1 (de) Dosierungsform eines Pulveragglomerates
EE04420B1 (et) Pulberinhalaator
DE69625036D1 (de) Volumetrische Pulverzuführvorrichtung
EE200000383A (et) Peroraalne farmatseutiline pikendatud vabanemisega annusvorm
DE69428743D1 (de) Trockenpulverinhalator
GB9700504D0 (en) Pharmaceutical compounds
DE69331635D1 (de) Pulverinhalator
EP1003495A4 (de) Pharmazeutische verbindungen
DE69823492D1 (de) Körniges modifiziertes polytetrafluoroethylenpulver
ATE295150T1 (de) Pharmazeutische zusammensetzungen
DE59509148D1 (de) Puderbestäubungsgerät
NO20003182L (no) FremgangsmÕte for inhalering av pulverstoffer
PL338781A1 (en) Dosage form
EE200000401A (et) Farmatseutilise preparaadi valmistamismeetod
GB9700895D0 (en) Pharmaceutical compounds
ID19844A (id) Komponen tumbukan
AU5343498A (en) Thiophene compounds and medicinal use thereof
DE29617541U1 (de) Pulverstreumaschine
HUP0004274A3 (en) Bispyrido-cycloheptane compounds and pharmaceutical compositions thereof
KR940024237U (ko) 과립형 분말 흡입기
KR940018782U (ko) 과립형 분말 흡입기
GB9718683D0 (en) Novel dosage form
SE9703829D0 (sv) Powder inhaleri
IL120172A0 (en) Pharmaceutical dosage form
GB9712357D0 (en) Pharmaceutical dosage form

Legal Events

Date Code Title Description
8364 No opposition during term of opposition