DE69837163T2 - Iontophoretische vorrichtung mit programmierbarer elektrischer stromeinstellung - Google Patents
Iontophoretische vorrichtung mit programmierbarer elektrischer stromeinstellung Download PDFInfo
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- DE69837163T2 DE69837163T2 DE69837163T DE69837163T DE69837163T2 DE 69837163 T2 DE69837163 T2 DE 69837163T2 DE 69837163 T DE69837163 T DE 69837163T DE 69837163 T DE69837163 T DE 69837163T DE 69837163 T2 DE69837163 T2 DE 69837163T2
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- 229940002612 prodrug Drugs 0.000 description 1
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- 150000003180 prostaglandins Chemical class 0.000 description 1
- 229960000856 protein c Drugs 0.000 description 1
- 239000003368 psychostimulant agent Substances 0.000 description 1
- 239000002461 renin inhibitor Substances 0.000 description 1
- 229940086526 renin-inhibitors Drugs 0.000 description 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 description 1
- 229960001634 ritodrine Drugs 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 description 1
- 229960000553 somatostatin Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
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- 229960005202 streptokinase Drugs 0.000 description 1
- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 229940064707 sympathomimetics Drugs 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 229960003604 testosterone Drugs 0.000 description 1
- GKCBAIGFKIBETG-UHFFFAOYSA-N tetracaine Chemical compound CCCCNC1=CC=C(C(=O)OCCN(C)C)C=C1 GKCBAIGFKIBETG-UHFFFAOYSA-N 0.000 description 1
- 229960002372 tetracaine Drugs 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
- LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 229960000187 tissue plasminogen activator Drugs 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 229960004371 urofollitropin Drugs 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 229960001722 verapamil Drugs 0.000 description 1
- 229940075420 xanthine Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
- Medicinal Preparation (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Apparatuses And Processes For Manufacturing Resistors (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6985897P | 1997-12-17 | 1997-12-17 | |
| US69858P | 1997-12-17 | ||
| PCT/US1998/025645 WO1999030775A1 (en) | 1997-12-17 | 1998-12-02 | Iontophoresis with programmed adjustment of electric current |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69837163D1 DE69837163D1 (de) | 2007-04-05 |
| DE69837163T2 true DE69837163T2 (de) | 2007-11-22 |
Family
ID=22091649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69837163T Expired - Lifetime DE69837163T2 (de) | 1997-12-17 | 1998-12-02 | Iontophoretische vorrichtung mit programmierbarer elektrischer stromeinstellung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6219576B1 (https=) |
| EP (1) | EP1047475B1 (https=) |
| JP (2) | JP4362012B2 (https=) |
| AT (1) | ATE354400T1 (https=) |
| AU (1) | AU1622999A (https=) |
| CY (1) | CY1106591T1 (https=) |
| DE (1) | DE69837163T2 (https=) |
| DK (1) | DK1047475T3 (https=) |
| ES (1) | ES2281940T3 (https=) |
| PT (1) | PT1047475E (https=) |
| WO (1) | WO1999030775A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| US20050058701A1 (en) * | 2003-01-29 | 2005-03-17 | Yossi Gross | Active drug delivery in the gastrointestinal tract |
| CN1774239A (zh) * | 2003-01-29 | 2006-05-17 | 埃-皮尔制药公司 | 用于胃肠道的有效药物递送 |
| WO2006064502A2 (en) * | 2004-12-14 | 2006-06-22 | E-Pill Pharma, Ltd. | Local delivery of drugs or substances using electronic permeability increase |
| US10130801B1 (en) * | 2005-02-07 | 2018-11-20 | Ipventure, Inc. | Electronic transdermal chemical delivery |
| JP2008540023A (ja) * | 2005-05-19 | 2008-11-20 | イー−ピル ファーマ リミティド | 組織における一酸化窒素生成のための摂取可能デバイス |
| US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
| US20090043244A1 (en) * | 2007-08-08 | 2009-02-12 | Inan Omer T | Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change |
| US20090105632A1 (en) * | 2007-10-18 | 2009-04-23 | Padmanabhan Rama V | Electrotransport Of Lisuride |
| US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
| WO2009123970A2 (en) * | 2008-04-01 | 2009-10-08 | Alza Corporation | Electrotransport fentanyl delivery device with consistent delivery |
| US20090259176A1 (en) * | 2008-04-09 | 2009-10-15 | Los Gatos Research, Inc. | Transdermal patch system |
| US20090312689A1 (en) * | 2008-06-05 | 2009-12-17 | Alza Corporation | Adjustable Current Electrotransport Fentanyl Delivery Device |
| WO2010078313A1 (en) | 2008-12-30 | 2010-07-08 | Nupathe, Inc. | Electronic control of drug delivery system |
| US20100286628A1 (en) * | 2009-05-07 | 2010-11-11 | Rainbow Medical Ltd | Gastric anchor |
| US8414559B2 (en) * | 2009-05-07 | 2013-04-09 | Rainbow Medical Ltd. | Gastroretentive duodenal pill |
| US20100286587A1 (en) * | 2009-05-07 | 2010-11-11 | Yossi Gross | Sublingual electrical drug delivery |
| US20110066175A1 (en) * | 2009-05-07 | 2011-03-17 | Rainbow Medical Ltd. | Gastric anchor |
| WO2011130455A1 (en) | 2010-04-13 | 2011-10-20 | Najib Babul | Dermal pharmaceutical compositions of 1-methyl-2',6'-pipecoloxylidide and method of use |
| AU2011332187B2 (en) | 2010-11-23 | 2016-03-03 | Teva Pharmaceuticals International Gmbh | User-activated self-contained co-packaged iontophoretic drug delivery system |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3991755A (en) | 1973-07-27 | 1976-11-16 | Medicon, Inc. | Iontophoresis apparatus for applying local anesthetics |
| US4141359A (en) | 1976-08-16 | 1979-02-27 | University Of Utah | Epidermal iontophoresis device |
| US4250878A (en) | 1978-11-22 | 1981-02-17 | Motion Control, Inc. | Non-invasive chemical species delivery apparatus and method |
| BR8008859A (pt) | 1979-10-10 | 1981-08-25 | Cyclotech Med Ind | Bandagem bloqueadora de dor |
| US4383529A (en) | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
| US4856188A (en) | 1984-10-12 | 1989-08-15 | Drug Delivery Systems Inc. | Method for making disposable and/or replenishable transdermal drug applicators |
| US5865786A (en) * | 1983-08-18 | 1999-02-02 | Drug Delivery Systems, Inc. | Programmable control and mounting system for transdermal drug applicator |
| CA1262564A (en) | 1983-09-01 | 1989-10-31 | Minoru Sasaki | Iontophoresis device |
| BR8507219A (pt) * | 1985-06-10 | 1987-08-04 | Drug Delivery Systems Inc | Sistema de montagem e controle programavel para aplicador de droga transdermico |
| US4886489A (en) | 1986-03-19 | 1989-12-12 | Jacobsen Stephen C | Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH |
| US4931046A (en) * | 1987-05-15 | 1990-06-05 | Newman Martin H | Iontophoresis drug delivery system |
| EP0313638A4 (en) * | 1987-05-15 | 1989-06-14 | Martin H Newman | IONTOPHORESIS INOPHORESIS DRUG ADMINISTRATION SYSTEM. |
| US5013293A (en) | 1987-05-28 | 1991-05-07 | Drug Delivery Systems Inc. | Pulsating transdermal drug delivery system |
| US4942883A (en) | 1987-09-29 | 1990-07-24 | Newman Martin H | Drug delivery device |
| US5162042A (en) | 1988-07-05 | 1992-11-10 | Alza Corporation | Electrotransport transdermal system |
| US5006108A (en) | 1988-11-16 | 1991-04-09 | Noven Pharmaceuticals, Inc. | Apparatus for iontophoretic drug delivery |
| DK0522043T3 (da) | 1990-03-30 | 2004-02-23 | Alza Corp | Iontoforetisk indgivelsesindretning |
| US5207752A (en) | 1990-03-30 | 1993-05-04 | Alza Corporation | Iontophoretic drug delivery system with two-stage delivery profile |
| US5213568A (en) | 1990-03-30 | 1993-05-25 | Medtronic Inc. | Activity controlled electrotransport drug delivery device |
| US5125894A (en) | 1990-03-30 | 1992-06-30 | Alza Corporation | Method and apparatus for controlled environment electrotransport |
| NL9100662A (nl) * | 1991-04-17 | 1992-11-16 | Optische Ind De Oude Delft Nv | Inrichting voor het uitvoeren van een iontoforese-behandeling bij een patient. |
| US5421817A (en) | 1991-05-21 | 1995-06-06 | E.P., Inc. | Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system |
| US5427585A (en) * | 1993-03-29 | 1995-06-27 | Bettinger; David S. | On-demand iontophoretic system |
| DE69430575T2 (de) | 1993-06-08 | 2002-10-02 | Hisamitsu Pharmaceutical Co., Inc. | Iontophoretisches system |
| US5387189A (en) | 1993-12-02 | 1995-02-07 | Alza Corporation | Electrotransport delivery device and method of making same |
| US5498235A (en) | 1994-09-30 | 1996-03-12 | Becton Dickinson And Company | Iontophoresis assembly including patch/controller attachment |
| US6167301A (en) * | 1995-08-29 | 2000-12-26 | Flower; Ronald J. | Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit |
| US5688232A (en) | 1995-09-28 | 1997-11-18 | Becton Dickinson And Company | Iontophoretic drug delivery device having an improved controller |
| US5676648A (en) | 1996-05-08 | 1997-10-14 | The Aps Organization, Llp | Iontophoretic drug delivery apparatus and method for use |
| US5857994A (en) * | 1996-10-01 | 1999-01-12 | Becton, Dickinson And Company | Awakenable iontophoretic/delivery device for reducing electrical sensation upon application thereof |
| US6029083A (en) * | 1997-04-04 | 2000-02-22 | Becton, Dickinson And Company | Circuit and method for automatically turning off an iontophoresis system |
-
1998
- 1998-12-02 JP JP2000538750A patent/JP4362012B2/ja not_active Expired - Fee Related
- 1998-12-02 WO PCT/US1998/025645 patent/WO1999030775A1/en not_active Ceased
- 1998-12-02 DE DE69837163T patent/DE69837163T2/de not_active Expired - Lifetime
- 1998-12-02 DK DK98960687T patent/DK1047475T3/da active
- 1998-12-02 EP EP98960687A patent/EP1047475B1/en not_active Expired - Lifetime
- 1998-12-02 PT PT98960687T patent/PT1047475E/pt unknown
- 1998-12-02 ES ES98960687T patent/ES2281940T3/es not_active Expired - Lifetime
- 1998-12-02 AT AT98960687T patent/ATE354400T1/de active
- 1998-12-02 AU AU16229/99A patent/AU1622999A/en not_active Abandoned
- 1998-12-03 US US09/205,136 patent/US6219576B1/en not_active Expired - Lifetime
-
2007
- 2007-05-14 CY CY20071100654T patent/CY1106591T1/el unknown
-
2009
- 2009-05-25 JP JP2009125501A patent/JP2009219892A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1047475A1 (en) | 2000-11-02 |
| WO1999030775A1 (en) | 1999-06-24 |
| US6219576B1 (en) | 2001-04-17 |
| EP1047475B1 (en) | 2007-02-21 |
| JP2002508230A (ja) | 2002-03-19 |
| DE69837163D1 (de) | 2007-04-05 |
| PT1047475E (pt) | 2007-04-30 |
| ES2281940T3 (es) | 2007-10-01 |
| DK1047475T3 (da) | 2007-06-11 |
| JP4362012B2 (ja) | 2009-11-11 |
| JP2009219892A (ja) | 2009-10-01 |
| ATE354400T1 (de) | 2007-03-15 |
| CY1106591T1 (el) | 2012-01-25 |
| AU1622999A (en) | 1999-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8381 | Inventor (new situation) |
Inventor name: GUPTA, SUNEEL, K., SUNNYVALE, CA 94087, US Inventor name: HAAK, RONALD, P.K., PALO ALTO, CA 94301, US |
|
| 8364 | No opposition during term of opposition |