DE69834736D1 - Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl-derivate - Google Patents

Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl-derivate

Info

Publication number
DE69834736D1
DE69834736D1 DE69834736T DE69834736T DE69834736D1 DE 69834736 D1 DE69834736 D1 DE 69834736D1 DE 69834736 T DE69834736 T DE 69834736T DE 69834736 T DE69834736 T DE 69834736T DE 69834736 D1 DE69834736 D1 DE 69834736D1
Authority
DE
Germany
Prior art keywords
compounds
biotransformation
colchicon
glycosyl derivatives
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69834736T
Other languages
English (en)
Other versions
DE69834736T2 (de
Inventor
Ezio Bombardelli
Cesare Ponzone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indena SpA
Original Assignee
Indena SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena SpA filed Critical Indena SpA
Application granted granted Critical
Publication of DE69834736D1 publication Critical patent/DE69834736D1/de
Publication of DE69834736T2 publication Critical patent/DE69834736T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69834736T 1997-10-03 1998-09-30 Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl-derivate Expired - Lifetime DE69834736T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI972255 1997-10-03
IT97MI002255A IT1295272B1 (it) 1997-10-03 1997-10-03 Biotrasformazione di composti colchiconici nei corrispondenti 3- glicosilderivati
PCT/EP1998/006226 WO1999018229A1 (en) 1997-10-03 1998-09-30 A process for the biotransformation of colchicone compounds into the corresponding 3-glycosyl derivatives

Publications (2)

Publication Number Publication Date
DE69834736D1 true DE69834736D1 (de) 2006-07-06
DE69834736T2 DE69834736T2 (de) 2007-05-10

Family

ID=11377985

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69834736T Expired - Lifetime DE69834736T2 (de) 1997-10-03 1998-09-30 Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl-derivate

Country Status (21)

Country Link
US (1) US6372458B1 (de)
EP (1) EP1019521B1 (de)
KR (1) KR100536676B1 (de)
CN (1) CN1188527C (de)
AT (1) ATE328106T1 (de)
AU (1) AU745222B2 (de)
CA (1) CA2305046C (de)
CZ (1) CZ295749B6 (de)
DE (1) DE69834736T2 (de)
DK (1) DK1019521T3 (de)
ES (1) ES2264214T3 (de)
HK (1) HK1031896A1 (de)
HU (1) HU225686B1 (de)
IL (1) IL134566A (de)
IT (1) IT1295272B1 (de)
NO (1) NO320096B1 (de)
PL (1) PL190865B1 (de)
PT (1) PT1019521E (de)
RU (1) RU2218409C2 (de)
SK (1) SK285923B6 (de)
WO (1) WO1999018229A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040175782A1 (en) * 2003-03-06 2004-09-09 Tethys Research Llc Biotransformation of compounds using non-prokaryotic microalgae
US7910334B2 (en) * 2004-05-12 2011-03-22 Indena S.P.A. Biotransformation of colchicinoid compounds
KR20140014072A (ko) * 2010-09-22 2014-02-05 엘리시안 라이프 사이언스이즈 프라이빗 리미티드 콜키시노이드 화합물의 미생물학적 생물전환 방법
EP3086794B1 (de) 2013-12-23 2020-01-08 Alkaloids Corporation Verfahren zur umwandlung von colchicinoiden in ihre 3-glycosylierten derivate über ihre jeweiligen 3-demethylanaloga
CN105861601B (zh) * 2016-04-29 2019-05-24 中国药科大学 一种生物转化制备二氢去氢双松柏醇葡萄糖单糖苷(hmzg)的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1344157A (fr) * 1959-05-22 1963-11-29 Roussel Uclaf Nouvelles colchicines et leur procédé d'obtention
JPS5233195B2 (de) * 1971-09-30 1977-08-26
IT1285777B1 (it) * 1996-10-07 1998-06-18 Indena Spa Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati

Also Published As

Publication number Publication date
WO1999018229A1 (en) 1999-04-15
HUP0004840A2 (hu) 2001-04-28
HU225686B1 (en) 2007-06-28
CZ20001196A3 (cs) 2000-10-11
CN1188527C (zh) 2005-02-09
NO20001706D0 (no) 2000-04-03
PL339620A1 (en) 2001-01-02
IL134566A (en) 2004-06-20
PL190865B1 (pl) 2006-02-28
RU2218409C2 (ru) 2003-12-10
PT1019521E (pt) 2006-09-29
DE69834736T2 (de) 2007-05-10
SK4832000A3 (en) 2000-09-12
ITMI972255A1 (it) 1999-04-03
EP1019521A1 (de) 2000-07-19
IT1295272B1 (it) 1999-05-04
DK1019521T3 (da) 2006-10-02
CA2305046C (en) 2008-12-09
CN1273607A (zh) 2000-11-15
CA2305046A1 (en) 1999-04-15
CZ295749B6 (cs) 2005-10-12
KR20010030710A (ko) 2001-04-16
ES2264214T3 (es) 2006-12-16
HK1031896A1 (en) 2001-06-29
NO20001706L (no) 2000-06-05
KR100536676B1 (ko) 2005-12-14
EP1019521B1 (de) 2006-05-31
ATE328106T1 (de) 2006-06-15
SK285923B6 (sk) 2007-11-02
US6372458B1 (en) 2002-04-16
IL134566A0 (en) 2001-04-30
NO320096B1 (no) 2005-10-24
HUP0004840A3 (en) 2002-10-28
AU1028399A (en) 1999-04-27
AU745222B2 (en) 2002-03-14

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Legal Events

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8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC