ATE328106T1 - Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl- derivate - Google Patents

Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl- derivate

Info

Publication number
ATE328106T1
ATE328106T1 AT98952675T AT98952675T ATE328106T1 AT E328106 T1 ATE328106 T1 AT E328106T1 AT 98952675 T AT98952675 T AT 98952675T AT 98952675 T AT98952675 T AT 98952675T AT E328106 T1 ATE328106 T1 AT E328106T1
Authority
AT
Austria
Prior art keywords
compounds
biotransformation
colchicon
glycosyl derivatives
present
Prior art date
Application number
AT98952675T
Other languages
English (en)
Inventor
Ezio Bombardelli
Cesare Ponzone
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of ATE328106T1 publication Critical patent/ATE328106T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
AT98952675T 1997-10-03 1998-09-30 Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl- derivate ATE328106T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002255A IT1295272B1 (it) 1997-10-03 1997-10-03 Biotrasformazione di composti colchiconici nei corrispondenti 3- glicosilderivati

Publications (1)

Publication Number Publication Date
ATE328106T1 true ATE328106T1 (de) 2006-06-15

Family

ID=11377985

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98952675T ATE328106T1 (de) 1997-10-03 1998-09-30 Verfahren für die biotransformation von colchicon-verbindungen in die entsprechenden 3-glykosyl- derivate

Country Status (21)

Country Link
US (1) US6372458B1 (de)
EP (1) EP1019521B1 (de)
KR (1) KR100536676B1 (de)
CN (1) CN1188527C (de)
AT (1) ATE328106T1 (de)
AU (1) AU745222B2 (de)
CA (1) CA2305046C (de)
CZ (1) CZ295749B6 (de)
DE (1) DE69834736T2 (de)
DK (1) DK1019521T3 (de)
ES (1) ES2264214T3 (de)
HK (1) HK1031896A1 (de)
HU (1) HU225686B1 (de)
IL (1) IL134566A (de)
IT (1) IT1295272B1 (de)
NO (1) NO320096B1 (de)
PL (1) PL190865B1 (de)
PT (1) PT1019521E (de)
RU (1) RU2218409C2 (de)
SK (1) SK285923B6 (de)
WO (1) WO1999018229A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040175782A1 (en) * 2003-03-06 2004-09-09 Tethys Research Llc Biotransformation of compounds using non-prokaryotic microalgae
EP1745140B1 (de) * 2004-05-12 2009-08-26 Indena S.P.A. Biotransformation von colchicinoidverbindungen
WO2012038982A2 (en) * 2010-09-22 2012-03-29 Elysian Life Sciences Private Limited A microbial method for the biotransformation of colchicinoid compounds
WO2015097567A1 (en) 2013-12-23 2015-07-02 Alkaloids Corporation Process for the conversion of colchicinoids to their 3-glycosylated derivatives via their respective 3-demethyl analogues
CN105861601B (zh) * 2016-04-29 2019-05-24 中国药科大学 一种生物转化制备二氢去氢双松柏醇葡萄糖单糖苷(hmzg)的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1344157A (fr) * 1959-05-22 1963-11-29 Roussel Uclaf Nouvelles colchicines et leur procédé d'obtention
JPS5233195B2 (de) * 1971-09-30 1977-08-26
IT1285777B1 (it) * 1996-10-07 1998-06-18 Indena Spa Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati

Also Published As

Publication number Publication date
CA2305046A1 (en) 1999-04-15
CN1273607A (zh) 2000-11-15
SK285923B6 (sk) 2007-11-02
ITMI972255A1 (it) 1999-04-03
AU1028399A (en) 1999-04-27
WO1999018229A1 (en) 1999-04-15
NO20001706L (no) 2000-06-05
KR100536676B1 (ko) 2005-12-14
NO320096B1 (no) 2005-10-24
US6372458B1 (en) 2002-04-16
AU745222B2 (en) 2002-03-14
HU225686B1 (en) 2007-06-28
EP1019521A1 (de) 2000-07-19
EP1019521B1 (de) 2006-05-31
PL339620A1 (en) 2001-01-02
HUP0004840A2 (hu) 2001-04-28
CN1188527C (zh) 2005-02-09
NO20001706D0 (no) 2000-04-03
PL190865B1 (pl) 2006-02-28
PT1019521E (pt) 2006-09-29
SK4832000A3 (en) 2000-09-12
DE69834736T2 (de) 2007-05-10
IT1295272B1 (it) 1999-05-04
ES2264214T3 (es) 2006-12-16
KR20010030710A (ko) 2001-04-16
CZ295749B6 (cs) 2005-10-12
DK1019521T3 (da) 2006-10-02
IL134566A0 (en) 2001-04-30
CA2305046C (en) 2008-12-09
DE69834736D1 (de) 2006-07-06
CZ20001196A3 (cs) 2000-10-11
HUP0004840A3 (en) 2002-10-28
RU2218409C2 (ru) 2003-12-10
IL134566A (en) 2004-06-20
HK1031896A1 (en) 2001-06-29

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