DE69834334D1 - Für adipozyten spezifische protein homologe - Google Patents

Für adipozyten spezifische protein homologe

Info

Publication number
DE69834334D1
DE69834334D1 DE69834334T DE69834334T DE69834334D1 DE 69834334 D1 DE69834334 D1 DE 69834334D1 DE 69834334 T DE69834334 T DE 69834334T DE 69834334 T DE69834334 T DE 69834334T DE 69834334 D1 DE69834334 D1 DE 69834334D1
Authority
DE
Germany
Prior art keywords
homologist
adipocytes
specific protein
zsig39
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69834334T
Other languages
English (en)
Other versions
DE69834334T2 (de
Inventor
O Sheppard
M Humes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of DE69834334D1 publication Critical patent/DE69834334D1/de
Application granted granted Critical
Publication of DE69834334T2 publication Critical patent/DE69834334T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69834334T 1997-08-26 1998-08-26 Für adipozyten spezifische protein homologe Expired - Fee Related DE69834334T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5698397P 1997-08-26 1997-08-26
US56983P 1997-08-26
PCT/US1998/017724 WO1999010492A1 (en) 1997-08-26 1998-08-26 Adipocyte-specific protein homologs

Publications (2)

Publication Number Publication Date
DE69834334D1 true DE69834334D1 (de) 2006-06-01
DE69834334T2 DE69834334T2 (de) 2007-04-26

Family

ID=22007782

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69834334T Expired - Fee Related DE69834334T2 (de) 1997-08-26 1998-08-26 Für adipozyten spezifische protein homologe

Country Status (11)

Country Link
US (3) US6197930B1 (de)
EP (1) EP1009829B1 (de)
JP (1) JP3492999B2 (de)
KR (1) KR20010023325A (de)
CN (1) CN1272884A (de)
AT (1) ATE324443T1 (de)
AU (1) AU744254B2 (de)
CA (1) CA2301660A1 (de)
DE (1) DE69834334T2 (de)
NO (1) NO20000934L (de)
WO (1) WO1999010492A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469158B1 (en) * 1992-05-14 2002-10-22 Ribozyme Pharmaceuticals, Incorporated Synthesis, deprotection, analysis and purification of RNA and ribozymes
US6642360B2 (en) * 1997-12-03 2003-11-04 Genentech, Inc. Secreted polypeptides that stimulate release of proteoglycans from cartilage
FR2767135B1 (fr) 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
US20020132981A1 (en) * 1997-12-03 2002-09-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2002504327A (ja) * 1998-02-23 2002-02-12 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー セレベリン−２関連ポリペプチドおよび該ポリペプチドをコードするｄｎａ
US6406884B1 (en) * 1999-06-18 2002-06-18 Millennium Pharmaceuticals, Inc. Secreted proteins and uses thereof
WO2000026363A1 (en) 1998-11-04 2000-05-11 Genset GENOMIC AND COMPLETE cDNA SEQUENCES OF HUMAN ADIPOCYTE-SPECIFIC APM1 AND BIALLELIC MARKERS THEREOF
ES2323445T3 (es) 1999-02-10 2009-07-16 Serono Genetics Institute S.A. Marcadores polimorficos del gen lsr.
CN1341027A (zh) 1999-02-19 2002-03-20 津莫吉尼蒂克斯公司 止血和免疫功能的抑制剂
US6544946B1 (en) 1999-02-19 2003-04-08 Zymogenetics, Inc. Inhibitors for use in hemostasis and immune function
US20050042719A1 (en) * 1999-05-27 2005-02-24 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
WO2000073448A1 (en) * 1999-05-27 2000-12-07 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp7
WO2001032868A1 (en) * 1999-11-04 2001-05-10 Genset Apm1 biallelic markers and uses thereof
US6579852B2 (en) * 2000-01-14 2003-06-17 Genset S.A. OBG3 globular head and uses thereof for decreasing body mass
US20020058617A1 (en) * 2000-01-14 2002-05-16 Joachim Fruebis OBG3 globular head and uses thereof for decreasing body mass
US7338787B2 (en) * 2000-01-14 2008-03-04 Serono Genetics Institute S.A. Nucleic acids encoding OBG3 globular head and uses thereof
US6989367B2 (en) * 2000-01-14 2006-01-24 Genset S.A. OBG3 globular head and uses thereof
US6566332B2 (en) * 2000-01-14 2003-05-20 Genset S.A. OBG3 globular head and uses thereof for decreasing body mass
AU2002249529B2 (en) * 2001-01-16 2007-03-22 Serono Genetics Institute S.A. GMG-3, GMG-4, and GMG-6 polynucleotides and polypeptides and uses thereof
EP1422241A1 (de) 2002-11-19 2004-05-26 Alexander Steinkasserer Verwendung der löslichen Formen des CD83 und dafür kodierender Nukleinsäuren zur Behandlung oder Vorbeugung von Krankheiten
US7169898B2 (en) 2002-12-04 2007-01-30 Alexander Steinkasserer Soluble CD83 proteins and use thereof for the treatment or prevention of a disease or medical condition caused by dysfunction or undesired function of a cellular immune response involving T cells
US9102726B2 (en) * 2002-12-04 2015-08-11 Argos Therapeutics, Inc. Nucleic acid of recombination expression vector encoding soluble forms of CD83, host cells transformed/transfected therewith and pharmaceutical compositions containing same
JP2011520959A (ja) * 2008-05-23 2011-07-21 アルゴス・セラピューティクス・インコーポレーテッド 新規可溶性ｃｄ８３ポリペプチド、配合物および使用法
CN102940875B (zh) * 2012-10-31 2015-09-30 中国人民解放军军事医学科学院微生物流行病研究所 Paa蛋白及由其制备的抗体与应用
EP4252769A3 (de) 2013-07-09 2023-11-29 Annexon, Inc. Anti-komplementfaktor-c1q-antikörper und verwendungen davon
CN107207587B (zh) 2014-11-05 2022-04-19 安尼艾克松股份有限公司 人源化抗-补体因子c1q抗体及其应用
BR112018010360A2 (pt) 2015-11-24 2018-12-04 Annexon Inc fragmentos fab de fator de complemento anti-c1q e utilizações dos mesmos
CN110195070B (zh) * 2019-05-31 2022-11-04 天津大学 大肠杆菌全局调控因子的突变基因crp及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869330A (en) 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
WO1999035170A2 (en) 1998-01-05 1999-07-15 Genentech, Inc. Compositions and methods for the treatment of tumor
NZ504548A (en) 1997-12-03 2003-06-30 Genentech Inc Polypeptides and nucleic acids encoding human chordin
US6406884B1 (en) 1999-06-18 2002-06-18 Millennium Pharmaceuticals, Inc. Secreted proteins and uses thereof
KR20010086072A (ko) 1998-12-01 2001-09-07 제넨테크, 인크. 신생 세포 성장 억제를 위한 방법 및 조성물
CA2353775A1 (en) 1998-12-22 2000-06-29 Genentech, Inc. Compositions and methods for the treatment of tumor
AU3514400A (en) 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of immune related diseases

Also Published As

Publication number Publication date
JP2001513998A (ja) 2001-09-11
CN1272884A (zh) 2000-11-08
EP1009829A1 (de) 2000-06-21
KR20010023325A (ko) 2001-03-26
AU9036298A (en) 1999-03-16
NO20000934D0 (no) 2000-02-25
WO1999010492A1 (en) 1999-03-04
NO20000934L (no) 2000-04-26
EP1009829B1 (de) 2006-04-26
AU744254B2 (en) 2002-02-21
US20030171547A1 (en) 2003-09-11
CA2301660A1 (en) 1999-03-04
US6197930B1 (en) 2001-03-06
ATE324443T1 (de) 2006-05-15
US6482612B1 (en) 2002-11-19
JP3492999B2 (ja) 2004-02-03
DE69834334T2 (de) 2007-04-26

Similar Documents

Publication Publication Date Title
DE69834334D1 (de) Für adipozyten spezifische protein homologe
PL338139A1 (en) Protein homologues specific for adipocytes
ATE332368T1 (de) Selektion von proteinen mittels rns-protein fusionen
EA200000216A1 (ru) Белки, связывающие интерлейкин-18, их получение и применение
NZ504114A (en) Vitamin k-dependent polypeptides such as protein C where substitution at amino acid sites 11, 12, 29, 33 or 34 affects membrane binding affinity of the protein and ultimately blood clotting ability
EA200001023A1 (ru) Специфическое в отношении fapa-(протеин альфа активации фибробласта) антитело с повышенной продуктивностью
ATE172743T1 (de) Nachweis von kollagenabbau -i(in vivo)
ATE349700T1 (de) Übergangsmetallkomplex-haltige lumineszente proteinfarben
PT1140175E (pt) Anticorpos para o vegf-d truncado e suas utilizacoes
ATE265542T1 (de) Verfahren zur hochauflösenden identifizierung von lösungsmittel-zugänglichen amidhydrogenen in polypeptiden
ATE372384T1 (de) Protein-tyrosin-phosphatase ptp-s31
BR9509172A (pt) Proteina de via de complemento nativa sequéncia de dna construção de dna conjugado uso de uma proteína processo para reduzir proteina de via de complemento em um mamifero e formulação farmacéutica
DE60129239D1 (de) Kit und verfahren zur bestimmung von protein esm-1
ATE323764T1 (de) Kappa/mu ähnliche proteintyrosinphosphatase, proteintyrosinphosphatase lambda
DE69831084D1 (de) Beta-defensine
DK0968288T3 (da) z219a, en human homolog til 2-19 protein
NO922421D0 (no) Collagenbindende protein, samt fremstilling derav
DE69224631D1 (de) Bindendes protein fixierungstest.
WO2002059282A3 (en) Adipocyte complement related protein zacrp13
WO2000073446A3 (en) Adipocyte complement related protein homolog zacrp6
NO20015114L (no) Adipocyttkomplementbeslektet proteinhomolog zacrp2
WO2002044373A3 (en) Adipocyte complement related protein zacrp12
WO2002070704A3 (en) Adipocyte complement related protein zacrp11
Foucher et al. Resolution of adiponectin oligomers in human plasma using free flow electrophoresis
EA199900663A1 (ru) Новые белки, связывающиеся с рецептором 1 интерферона, кодирующая их днк и способы модуляции клеточного ответа на интерфероны

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee