DE69833651D1 - Verwendung hochdosierter retinoide zur behandlung von lichtgeschädigter haut - Google Patents
Verwendung hochdosierter retinoide zur behandlung von lichtgeschädigter hautInfo
- Publication number
- DE69833651D1 DE69833651D1 DE69833651T DE69833651T DE69833651D1 DE 69833651 D1 DE69833651 D1 DE 69833651D1 DE 69833651 T DE69833651 T DE 69833651T DE 69833651 T DE69833651 T DE 69833651T DE 69833651 D1 DE69833651 D1 DE 69833651D1
- Authority
- DE
- Germany
- Prior art keywords
- tretinoin
- skin
- vehicle
- weight percent
- treated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 6
- 229960001727 tretinoin Drugs 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- 208000017520 skin disease Diseases 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 206010003694 Atrophy Diseases 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 206010066295 Keratosis pilaris Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010051246 Photodermatosis Diseases 0.000 abstract 1
- 241001303601 Rosacea Species 0.000 abstract 1
- 206010040844 Skin exfoliation Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 230000037444 atrophy Effects 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 230000035618 desquamation Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000001804 emulsifying effect Effects 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 230000003810 hyperpigmentation Effects 0.000 abstract 1
- 208000000069 hyperpigmentation Diseases 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 201000004700 rosacea Diseases 0.000 abstract 1
- 230000037390 scarring Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4607097P | 1997-05-09 | 1997-05-09 | |
US46070P | 1997-05-09 | ||
US09/071,017 US6008254A (en) | 1997-05-09 | 1998-05-01 | Method of treating skin disorders with high-strength tretinoin |
US71017 | 1998-05-01 | ||
PCT/US1998/009440 WO1998050023A1 (en) | 1997-05-09 | 1998-05-11 | Use of high dose retinoids for the treatment of skin disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69833651D1 true DE69833651D1 (de) | 2006-04-27 |
DE69833651T2 DE69833651T2 (de) | 2006-12-28 |
Family
ID=26723533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69833651T Expired - Fee Related DE69833651T2 (de) | 1997-05-09 | 1998-05-11 | Verwendung hochdosierter retinoide zur behandlung von lichtgeschädigter haut |
Country Status (8)
Country | Link |
---|---|
US (2) | US6008254A (de) |
EP (1) | EP0980243B1 (de) |
AT (1) | ATE318593T1 (de) |
AU (1) | AU7374998A (de) |
CA (1) | CA2288706C (de) |
DE (1) | DE69833651T2 (de) |
ES (1) | ES2260834T3 (de) |
WO (1) | WO1998050023A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6008254A (en) * | 1997-05-09 | 1999-12-28 | Kligman; Douglas E. | Method of treating skin disorders with high-strength tretinoin |
US8263580B2 (en) * | 1998-09-11 | 2012-09-11 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
AUPP583198A0 (en) * | 1998-09-11 | 1998-10-01 | Soltec Research Pty Ltd | Mousse composition |
MXPA02010564A (es) * | 2000-04-28 | 2003-03-10 | Hoffmann La Roche | Heteroarilos y p-(sulfonil)-arilos. |
US6353029B1 (en) | 2000-08-24 | 2002-03-05 | Bristol-Myers Squibb Company | Storage stable tretinoin and 4-hydroxyanisole containing topical composition |
EP1385496A4 (de) | 2001-05-09 | 2006-03-29 | Univ Michigan | Verwendung von zusammensetzungen zur behandlung von rosacea |
WO2003057162A2 (en) * | 2002-01-04 | 2003-07-17 | Combinatorx, Incorporated | Combination for the treatment of immunoinflammatory disorders and proliferative skin diseases |
US20040097587A1 (en) * | 2002-03-27 | 2004-05-20 | Arbiser Jack L | Compositions and methods of treatment of ulcerating diseases, burns, and related conditions |
US7390499B2 (en) | 2002-04-26 | 2008-06-24 | Lohmann & Rauscher Gmbh | Microbial cellulose wound dressing for treating chronic wounds |
US7704523B2 (en) * | 2002-04-26 | 2010-04-27 | Lohmann & Rauscher Gmbh | Microbial cellulose wound dressing for treating chronic wounds |
US20050019380A1 (en) * | 2002-04-26 | 2005-01-27 | Xylos Corporation | Microbial cellulose wound dressing for treating chronic wounds |
US20030203013A1 (en) * | 2002-04-26 | 2003-10-30 | Xylos Corporation | Microbial cellulose wound dressing for treating chronic wounds |
JP2007523156A (ja) * | 2004-02-19 | 2007-08-16 | ケマファー インコーポレイティッド | 皮膚状態の処置用の局所製剤 |
FR2870125B1 (fr) * | 2004-05-12 | 2010-03-26 | Dermaconcept Jmc | Formulation du type spot-on utile en cosmetologie et en dermatologie |
SG155959A1 (en) | 2004-09-28 | 2009-10-29 | Chemaphor Inc | Compositions and methods for promoting weight gain and feed conversion |
KR20070089143A (ko) * | 2004-12-02 | 2007-08-30 | 오엠피, 인코포레이티드 | 피부에 유익한 제제의 경피 흡수 향상을 위한 시스템 |
JP2008534514A (ja) * | 2005-03-24 | 2008-08-28 | アナコール ファーマシューティカルズ,インコーポレイテッド | ボリン酸抗生物質の局所製剤およびそれらの使用法 |
NZ563560A (en) * | 2005-06-01 | 2009-11-27 | Stiefel Res Australia Pty Ltd | Vitamin formulation for treating a dermatological skin disorder |
US20060294437A1 (en) * | 2005-06-22 | 2006-12-28 | Thunder Creative Technologies, Inc. | Point-of-load power conditioning for memory modules |
US7709631B2 (en) | 2006-03-13 | 2010-05-04 | Xylos Corporation | Oxidized microbial cellulose and use thereof |
US20070286884A1 (en) * | 2006-06-13 | 2007-12-13 | Xylos Corporation | Implantable microbial cellulose materials for hard tissue repair and regeneration |
US20100298249A1 (en) * | 2007-05-11 | 2010-11-25 | Marc Moutet | Pharmaceutical or cosmetic preparations for topical and/or parenteral application, preparation methods thereof and use of same |
AU2008316225B2 (en) * | 2007-10-26 | 2014-06-19 | Avivagen Inc. | Compositions and methods for enhancing immune response |
CA2975313C (en) | 2009-04-30 | 2020-06-30 | Avivagen Inc. | Methods and compositions for improving the health of animals |
EP3177365A4 (de) * | 2014-08-06 | 2018-01-10 | Thesan Pharmaceuticals, Inc. | Agonisten des ahr-rezeptorsignalweges mit sebosuppressiver aktivität und verfahren zur identifizierung dieser agonisten |
RU2018119510A (ru) * | 2015-10-30 | 2019-12-05 | Тимбер Фармасьютикалз ЭлЭлСи | Композиции изотретиноина и их применение и способы |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3729568A (en) * | 1969-09-23 | 1973-04-24 | Johnson & Johnson | Acne treatment |
US4603146A (en) * | 1984-05-16 | 1986-07-29 | Kligman Albert M | Methods for retarding the effects of aging of the skin |
US4888342A (en) * | 1984-05-16 | 1989-12-19 | Kligman Albert M | Methods for treatment of sundamaged human skin with retinoids |
US5019569A (en) * | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
AU636595B2 (en) * | 1989-01-19 | 1993-05-06 | Ortho Pharmaceutical Corporation | Method for the treatment or prevention of intrinsically aged skin with retinoids |
US5051449A (en) * | 1991-02-27 | 1991-09-24 | Kligman Albert M | Treatment of cellulite with retinoids |
AU1585692A (en) * | 1991-02-27 | 1992-10-06 | Albert M. Kligman | Methods for treatment of scarring fibrotic alopecia |
KR100282575B1 (ko) * | 1992-02-07 | 2001-02-15 | 알버트엠.클릭만 | 염증성 피부병치료용 약제학적 조성물 |
AU670777B2 (en) * | 1992-04-16 | 1996-08-01 | Ortho Pharmaceutical Corporation | Aqueous gel vehicles for retinoids |
US6008254A (en) * | 1997-05-09 | 1999-12-28 | Kligman; Douglas E. | Method of treating skin disorders with high-strength tretinoin |
-
1998
- 1998-05-01 US US09/071,017 patent/US6008254A/en not_active Expired - Lifetime
- 1998-05-11 EP EP98921064A patent/EP0980243B1/de not_active Expired - Lifetime
- 1998-05-11 AU AU73749/98A patent/AU7374998A/en not_active Abandoned
- 1998-05-11 ES ES98921064T patent/ES2260834T3/es not_active Expired - Lifetime
- 1998-05-11 DE DE69833651T patent/DE69833651T2/de not_active Expired - Fee Related
- 1998-05-11 CA CA002288706A patent/CA2288706C/en not_active Expired - Fee Related
- 1998-05-11 AT AT98921064T patent/ATE318593T1/de not_active IP Right Cessation
- 1998-05-11 WO PCT/US1998/009440 patent/WO1998050023A1/en active IP Right Grant
-
2000
- 2000-05-09 US US09/567,792 patent/US6228887B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6008254A (en) | 1999-12-28 |
EP0980243A1 (de) | 2000-02-23 |
WO1998050023A1 (en) | 1998-11-12 |
DE69833651T2 (de) | 2006-12-28 |
ES2260834T3 (es) | 2006-11-01 |
EP0980243B1 (de) | 2006-03-01 |
CA2288706A1 (en) | 1998-11-12 |
CA2288706C (en) | 2007-10-16 |
ATE318593T1 (de) | 2006-03-15 |
AU7374998A (en) | 1998-11-27 |
US6228887B1 (en) | 2001-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |