DE69832520D1 - Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetes - Google Patents

Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetes

Info

Publication number
DE69832520D1
DE69832520D1 DE69832520T DE69832520T DE69832520D1 DE 69832520 D1 DE69832520 D1 DE 69832520D1 DE 69832520 T DE69832520 T DE 69832520T DE 69832520 T DE69832520 T DE 69832520T DE 69832520 D1 DE69832520 D1 DE 69832520D1
Authority
DE
Germany
Prior art keywords
cis
octadecadienoic acid
diabetes
trans
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69832520T
Other languages
English (en)
Other versions
DE69832520T2 (de
Inventor
Heuvel P Vanden
A Belury
W Peck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penn State Research Foundation
Purdue Research Foundation
Original Assignee
Penn State Research Foundation
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penn State Research Foundation, Purdue Research Foundation filed Critical Penn State Research Foundation
Publication of DE69832520D1 publication Critical patent/DE69832520D1/de
Application granted granted Critical
Publication of DE69832520T2 publication Critical patent/DE69832520T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69832520T 1997-12-12 1998-12-11 Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetes Expired - Fee Related DE69832520T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6956797P 1997-12-12 1997-12-12
US69567P 1997-12-12
PCT/US1998/026469 WO1999029317A1 (en) 1997-12-12 1998-12-11 Methods and compositions for treating diabetes

Publications (2)

Publication Number Publication Date
DE69832520D1 true DE69832520D1 (de) 2005-12-29
DE69832520T2 DE69832520T2 (de) 2006-08-10

Family

ID=22089860

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832520T Expired - Fee Related DE69832520T2 (de) 1997-12-12 1998-12-11 Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetes

Country Status (9)

Country Link
US (1) US20050282897A1 (de)
EP (1) EP1037624B1 (de)
JP (1) JP2001525364A (de)
AT (1) ATE310511T1 (de)
AU (1) AU1911999A (de)
CA (1) CA2313626A1 (de)
DE (1) DE69832520T2 (de)
ES (1) ES2252874T3 (de)
WO (1) WO1999029317A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440931B1 (en) * 1999-02-23 2002-08-27 Natural Corporation Conjugated linoleic acid in treatment and prophylaxis of diabetes
WO2001003688A2 (en) * 1999-07-09 2001-01-18 Pharmacia Corporation Treatment of cyclooxygenase-2 mediated disorders using conjugated fatty acid compounds
JP2003508389A (ja) 1999-08-27 2003-03-04 エリ リリー アンド カンパニー ビアリール−オキサ（チア）ゾール誘導体およびそのｐｐａｒモジュレーターとしての使用
JP5226912B2 (ja) * 2000-06-12 2013-07-03 花王株式会社 Ｐｐａｒ活性化剤
US6927239B1 (en) 2000-08-02 2005-08-09 Pharmanutrients Methods and compositions for the attenuation and/or prevention of stress/catabolic responses
US6838451B1 (en) 2000-08-02 2005-01-04 Pharmanutrients Methods and compositions for the prevention and treatment of inflammation, osteoarthritis, and other degenerative joint diseases
JP2004505042A (ja) * 2000-08-02 2004-02-19 ファーマニュートリエンツ 糖尿病及びグルコース変性の予防及び／または治療のための方法及び組成物
EP1305017A4 (de) 2000-08-02 2004-01-14 Pharmanutrients Verfahren und zusammensetzung zur vorbeugung und behandlung von syndrom x
DE10045059A1 (de) * 2000-09-12 2002-03-21 Basf Ag Therapeutische Kombination von Liponsäure und Konjuensäuren zur Behandlung diabetischer Störungen
DE10102050A1 (de) 2001-01-17 2002-07-18 Basf Ag Zubereitung zur Verbesserung der Nahrungsverwertung
JP4220247B2 (ja) 2001-03-29 2009-02-04 ビーエーエスエフ ソシエタス・ヨーロピア 共役不飽和グリセリド混合物及びその製造方法
US6888016B2 (en) 2001-10-16 2005-05-03 Loders Croklaan Usa Llc Mixtures for stimulating glucose up-take
EP1302114A3 (de) * 2001-10-16 2004-01-14 Loders Croklaan B.V. Mischungen zur Förderung der Glucoseaufnahme
ES2748136T3 (es) 2007-10-15 2020-03-13 United Animal Health Inc Método para aumentar el rendimiento de las crías
AU2009282481A1 (en) * 2008-08-14 2010-02-18 Nestec S.A. Compositions and methods for influencing satiety, lipid metabolism, and fat utilization
JP6301844B2 (ja) 2012-02-09 2018-03-28 ノグラ ファーマ リミテッド 線維症の処置方法
US11255866B2 (en) 2015-02-26 2022-02-22 Wisconsin Alumni Research Foundation Methods for predicting glucoregulatory dysfunction via diacylglycerol fatty acid species concentrations
CA3014575A1 (en) * 2016-02-26 2017-08-31 Nogra Pharma Limited Methods of treating lactose intolerance
CN113825739A (zh) 2019-02-08 2021-12-21 诺格拉制药有限公司 制备3-(4’-氨基苯基)-2-甲氧基丙酸及其类似物和中间体的方法

Family Cites Families (26)

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Publication number Priority date Publication date Assignee Title
FR2490631A1 (fr) * 1980-09-24 1982-03-26 Roussel Uclaf Nouvelle composition lipidique utilisable en dietetique, reanimation et therapeutique
US4472432A (en) * 1982-05-12 1984-09-18 Inabata & Co., Ltd. Medicinal use of α,β-unsaturated fatty acids
GB8302708D0 (en) * 1983-02-01 1983-03-02 Efamol Ltd Pharmaceutical and dietary composition
US4871768A (en) * 1984-07-12 1989-10-03 New England Deaconess Hospital Corporation Dietary supplement utilizing ω-3/medium chain trigylceride mixtures
US5034415A (en) * 1987-08-07 1991-07-23 Century Laboratories, Inc. Treatment of diabetes mellitus
US5017614A (en) * 1989-02-17 1991-05-21 Wisconsin Alumni Research Foundation Methods of preventing oxidation, quenching singlet oxygen and inhibiting mold growth and novel compositions therefor
US5070104A (en) * 1989-02-17 1991-12-03 Wisconsin Alumni Research Foundation Methods of chelating metal and novel compositions therefor
US5208356A (en) * 1989-02-17 1993-05-04 Wisconsin Alumni Research Foundation Octadecadienoic phospholipic esters, antioxidant and mold inhibiting compositions
US5554646A (en) * 1992-04-29 1996-09-10 Wisconsin Alumni Research Foundation Method for reducing body fat in animals
US5430066A (en) * 1992-04-29 1995-07-04 Wisconsin Alumni Research Foundation Methods for preventing weight loss, reduction in weight gain, and anorexia due to immune stimulation
US5674901A (en) * 1995-06-01 1997-10-07 Wisconsin Alumni Research Foundation Methods of treating animals to maintain or increase CD-4 and CD-8 cell populations
US5504114A (en) * 1992-04-29 1996-04-02 Wisconsin Alumni Research Foundation Method for controlling bird populations
US5428072A (en) * 1992-04-29 1995-06-27 Wisconsin Alumni Research Foundation Method of increasing the efficiency of feed conversion in animals
AU673700B2 (en) * 1993-01-27 1996-11-21 Scotia Holdings Plc Triglycerides
NL9300848A (nl) * 1993-05-14 1994-12-01 Friesland Frico Domo Coop Werkwijze voor de bereiding van lang houdbare melkconcentraten en melkpoeders.
FR2723315B1 (fr) * 1994-08-02 1996-10-25 Cird Galderma Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes
US5760082C1 (en) * 1994-08-29 2001-03-06 Wisconsin Alumni Res Found Dietetic foods containing conjugated linoleic acids
US5518751A (en) * 1994-09-08 1996-05-21 Friesland Brands B.V. Process for the preparation of milk concentrates and milk powders having a long storage life
GB9508823D0 (en) * 1995-05-01 1995-06-21 Scotia Holdings Plc Drug Derivatives
US5585400A (en) * 1996-02-27 1996-12-17 Wisconsin Alumni Research Foundation Methods of attenuating the allergic response in animals
US5760083A (en) * 1996-08-07 1998-06-02 Wisconsin Alumni Research Foundation Use of CLA to reduce the incidence of valgus and varus leg deforomities in poultry
US5804210A (en) * 1996-08-07 1998-09-08 Wisconsin Alumni Research Foundation Methods of treating animals to maintain or enhance bone mineral content and compositions for use therein
GB9620248D0 (en) * 1996-09-26 1996-11-13 Scotia Holdings Plc Esters of unsaturated fatty acids
US5770247A (en) * 1996-10-03 1998-06-23 Wisconsin Alumni Research Foundation Method of increasing the CLA content of cow's milK
US7015249B1 (en) * 1997-12-12 2006-03-21 Purdue Research Foundation Methods and compositions for treating diabetes
US6440931B1 (en) * 1999-02-23 2002-08-27 Natural Corporation Conjugated linoleic acid in treatment and prophylaxis of diabetes

Also Published As

Publication number Publication date
EP1037624A4 (de) 2002-05-15
US20050282897A1 (en) 2005-12-22
JP2001525364A (ja) 2001-12-11
WO1999029317A1 (en) 1999-06-17
CA2313626A1 (en) 1999-06-17
EP1037624B1 (de) 2005-11-23
AU1911999A (en) 1999-06-28
EP1037624A1 (de) 2000-09-27
DE69832520T2 (de) 2006-08-10
ES2252874T3 (es) 2006-05-16
ATE310511T1 (de) 2005-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee