WO1999003456A3 - Method for prophylaxis or treatment of bone density loss - Google Patents

Method for prophylaxis or treatment of bone density loss Download PDF

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Publication number
WO1999003456A3
WO1999003456A3 PCT/EP1998/004187 EP9804187W WO9903456A3 WO 1999003456 A3 WO1999003456 A3 WO 1999003456A3 EP 9804187 W EP9804187 W EP 9804187W WO 9903456 A3 WO9903456 A3 WO 9903456A3
Authority
WO
WIPO (PCT)
Prior art keywords
prophylaxis
treatment
bone density
density loss
unsaturated fatty
Prior art date
Application number
PCT/EP1998/004187
Other languages
French (fr)
Other versions
WO1999003456A2 (en
Inventor
Pierre R Guesry
Original Assignee
Nestle Sa
Pierre R Guesry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestle Sa, Pierre R Guesry filed Critical Nestle Sa
Priority to AU88572/98A priority Critical patent/AU8857298A/en
Publication of WO1999003456A2 publication Critical patent/WO1999003456A2/en
Publication of WO1999003456A3 publication Critical patent/WO1999003456A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds

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  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A method for the prophylaxis or treatment of bone density loss in an animal or human. The method includes the step of administering to the animal or human an effective amount of a mono-unsaturated fatty acid. The mono-unsaturated fatty acid may form part of a lipid mixture which includes poly-unsaturated fatty acids.
PCT/EP1998/004187 1997-07-16 1998-07-06 Method for prophylaxis or treatment of bone density loss WO1999003456A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU88572/98A AU8857298A (en) 1997-07-16 1998-07-06 Method for prophylaxis or treatment of bone density loss

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5269197P 1997-07-16 1997-07-16
US60/052,691 1997-07-16

Publications (2)

Publication Number Publication Date
WO1999003456A2 WO1999003456A2 (en) 1999-01-28
WO1999003456A3 true WO1999003456A3 (en) 1999-04-15

Family

ID=21979280

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/004187 WO1999003456A2 (en) 1997-07-16 1998-07-06 Method for prophylaxis or treatment of bone density loss

Country Status (2)

Country Link
AU (1) AU8857298A (en)
WO (1) WO1999003456A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090196861A1 (en) * 2005-11-17 2009-08-06 Bioavailability, Inc. Biocompatible Latent Emulsifiers

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0517425A1 (en) * 1991-06-05 1992-12-09 Efamol Holdings Plc Fatty acids for the reduction of urinary calcium excretion and the treatment of osteoporosis
EP0585026A1 (en) * 1992-08-21 1994-03-02 Scotia Holdings Plc Use of fatty acids for increasing gut calcium absorption

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0517425A1 (en) * 1991-06-05 1992-12-09 Efamol Holdings Plc Fatty acids for the reduction of urinary calcium excretion and the treatment of osteoporosis
EP0585026A1 (en) * 1992-08-21 1994-03-02 Scotia Holdings Plc Use of fatty acids for increasing gut calcium absorption

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BARTELS T ET AL: "[Effect of linoleic acid in food on spongioid bone density and prostaglandin biosynthesis in bones]. Einfluss des Linolsauregehaltes der Nahrung auf Spongiosadichte und Prostaglandin--Biosynthese im Knochen.", BEITRAGE ZUR ORTHOPADIE UND TRAUMATOLOGIE, (1988 AUG) 35 (8) 353-9. JOURNAL CODE: 9N4. ISSN: 0005-8149., GERMANY, EAST: German Democratic Republic, XP002093684 *
HORROBIN, DAVID F.: "Essential fatty acid metabolism and bone.", BONE (NEW YORK), (1997) VOL. 20, NO. 4 SUPPL., PP. 120S. MEETING INFO.: 25TH EUROPEAN SYMPOSIUM ON CALCIFIED TISSUES HARROGATE, ENGLAND, UK APRIL 25-29, 1997 ISSN: 8756-3282., XP002093685 *
KREIDER, R. (1) ET AL: "Effects of conjugated linoleic acid (CLA) supplementation during resistance-training on bone mineral content, bone mineral density and markers of immune stress.", FASEB JOURNAL, (MARCH 17, 1998) VOL. 12, NO. 4, PP. A244. MEETING INFO.: ANNUAL MEETING OF THE PROFESSIONAL RESEARCH SCIENTISTS ON EXPERIMENTAL BIOLOGY 98, PART 1 SAN FRANCISCO, CALIFORNIA, USA APRIL 18-22, 1998 FEDERATION OF AMERICAN SOCIETIES FOR E, XP002093683 *
SEIFERT, MARK F. ET AL: "Role of dietary lipid and antioxidants in bone metabolism", NUTR. RES. (N. Y.) (1997), 17(7), 1209-1228 CODEN: NTRSDC;ISSN: 0271-5317, XP002093681 *
TRICHOPOULOU A. ET AL: "Energy intake and monounsaturated fat in relation to bone mineral density among women and men in Greece.", PREVENTIVE MEDICINE, (1997) 26/3 (395-400). REFS: 58 ISSN: 0091-7435 CODEN: PVTMA3, United States, XP002093682 *
WATKINS B A ET AL: "Dietary (n-3) and (n-6) polyunsaturates and acetylsalicylic acid alter ex vivo PGE2 biosynthesis, tissue IGF-I levels, and bone morphometry in chicks.", JOURNAL OF BONE AND MINERAL RESEARCH, (1996 SEP) 11 (9) 1321-32. JOURNAL CODE: 130. ISSN: 0884-0431., United States, XP002093680 *

Also Published As

Publication number Publication date
AU8857298A (en) 1999-02-10
WO1999003456A2 (en) 1999-01-28

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