DE69832167D1 - Identifizierung von gegenständen mittels mehrfacher bilderfassungen - Google Patents

Identifizierung von gegenständen mittels mehrfacher bilderfassungen

Info

Publication number
DE69832167D1
DE69832167D1 DE69832167T DE69832167T DE69832167D1 DE 69832167 D1 DE69832167 D1 DE 69832167D1 DE 69832167 T DE69832167 T DE 69832167T DE 69832167 T DE69832167 T DE 69832167T DE 69832167 D1 DE69832167 D1 DE 69832167D1
Authority
DE
Germany
Prior art keywords
brightfield
excitation
stained
fetal
fluorescence images
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69832167T
Other languages
English (en)
Other versions
DE69832167T2 (de
Inventor
Ilya Ravkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leica Microsystems San Jose Corp
Original Assignee
Applied Imaging Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Imaging Corp filed Critical Applied Imaging Corp
Application granted granted Critical
Publication of DE69832167D1 publication Critical patent/DE69832167D1/de
Publication of DE69832167T2 publication Critical patent/DE69832167T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G01N15/1433
    • G01N2015/012
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
DE69832167T 1997-05-14 1998-05-12 Identifizierung von gegenständen mittels mehrfacher bilderfassungen Expired - Lifetime DE69832167T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4647097P 1997-05-14 1997-05-14
US46470P 1997-05-14
US72502 1998-05-04
US09/072,502 US6169816B1 (en) 1997-05-14 1998-05-04 Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
PCT/US1998/009689 WO1998052018A1 (en) 1997-05-14 1998-05-12 Identification of objects by means of multiple imaging

Publications (2)

Publication Number Publication Date
DE69832167D1 true DE69832167D1 (de) 2005-12-08
DE69832167T2 DE69832167T2 (de) 2006-07-20

Family

ID=26723956

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832167T Expired - Lifetime DE69832167T2 (de) 1997-05-14 1998-05-12 Identifizierung von gegenständen mittels mehrfacher bilderfassungen

Country Status (11)

Country Link
US (1) US6169816B1 (de)
EP (1) EP0981732B1 (de)
JP (1) JP2002514304A (de)
AT (1) ATE308747T1 (de)
AU (1) AU739834B2 (de)
CA (1) CA2289930C (de)
DE (1) DE69832167T2 (de)
HK (1) HK1029170A1 (de)
IL (1) IL132747A (de)
NO (1) NO995542L (de)
WO (1) WO1998052018A1 (de)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6320697B2 (en) * 1931-08-07 2001-11-20 Nikon Corporation Illuminating light selection device for a microscope
US6215892B1 (en) * 1995-11-30 2001-04-10 Chromavision Medical Systems, Inc. Method and apparatus for automated image analysis of biological specimens
US6718053B1 (en) * 1996-11-27 2004-04-06 Chromavision Medical Systems, Inc. Method and apparatus for automated image analysis of biological specimens
US6259807B1 (en) * 1997-05-14 2001-07-10 Applied Imaging Corp. Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
KR100303608B1 (ko) * 1997-05-22 2001-11-22 박호군 혈구세포자동인식방법및장치
CN1702459A (zh) * 1998-05-09 2005-11-30 伊康尼西斯公司 用于包括胎儿细胞的计算机所控制的稀少细胞的基于诊断的方法和装置
AU772603B2 (en) * 1998-10-29 2004-05-06 Cell Works Diagnostics, Inc. Multiple marker characterization of single cells
US6539106B1 (en) * 1999-01-08 2003-03-25 Applied Materials, Inc. Feature-based defect detection
JP4624513B2 (ja) * 1999-01-19 2011-02-02 オリンパス株式会社 顕微鏡用撮像装置
AU2876900A (en) 1999-02-10 2000-08-29 Cell Works Inc. Class characterization of circulating cancer cells isolated from body fluids andmethods of use
DE19911988C2 (de) * 1999-03-17 2003-07-31 Siemens Ag Medizinische Magnetresonanzanlage
US6876760B1 (en) 2000-12-04 2005-04-05 Cytokinetics, Inc. Classifying cells based on information contained in cell images
US7151847B2 (en) * 2001-02-20 2006-12-19 Cytokinetics, Inc. Image analysis of the golgi complex
DE19932870A1 (de) * 1999-07-09 2001-04-05 Friedrich Schiller Uni Jena Bu Vorrichtung zur optischen Partikel- und Partikelströmungsanalyse
AU6867200A (en) * 1999-09-01 2001-03-26 Hamamatsu Photonics K.K. Feeble light color imaging device
WO2001033196A2 (en) * 1999-10-29 2001-05-10 Veracel Inc. Controlled review of medical sample
US6692952B1 (en) * 1999-11-10 2004-02-17 Massachusetts Institute Of Technology Cell analysis and sorting apparatus for manipulation of cells
US20060073509A1 (en) * 1999-11-18 2006-04-06 Michael Kilpatrick Method for detecting and quantitating multiple subcellular components
US6542180B1 (en) * 2000-01-07 2003-04-01 Mitutoyo Corporation Systems and methods for adjusting lighting of a part based on a plurality of selected regions of an image of the part
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US7668362B2 (en) 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
US7518652B2 (en) 2000-05-03 2009-04-14 Aperio Technologies, Inc. Method and apparatus for pre-focus in a linear array based slide scanner
US20020049544A1 (en) * 2000-06-23 2002-04-25 Cytokinetics, Inc. Image analysis for phenotyping sets of mutant cells
US7218764B2 (en) * 2000-12-04 2007-05-15 Cytokinetics, Inc. Ploidy classification method
US7016787B2 (en) * 2001-02-20 2006-03-21 Cytokinetics, Inc. Characterizing biological stimuli by response curves
US6956961B2 (en) * 2001-02-20 2005-10-18 Cytokinetics, Inc. Extracting shape information contained in cell images
SE517626C3 (sv) * 2001-04-12 2002-09-04 Cellavision Ab Förfarande vid mikroskopering för att söka av och positionera ett objekt, där bilder tas och sammanfogas i samma bildkoordinatsystem för att noggrant kunna ställa in mikroskopbordet
EP1404875A1 (de) * 2001-06-08 2004-04-07 ChemoMetec A/S Verfahren und system zur zählung von zellen mehrerer spezies
US7133543B2 (en) * 2001-06-12 2006-11-07 Applied Imaging Corporation Automated scanning method for pathology samples
JP3766421B2 (ja) * 2001-07-03 2006-04-12 株式会社日立製作所 生体試料光学測定方法及び生体試料光学測定装置
US7336988B2 (en) * 2001-08-08 2008-02-26 Lucent Technologies Inc. Multi-photon endoscopy
US8676509B2 (en) * 2001-11-13 2014-03-18 Dako Denmark A/S System for tracking biological samples
US20050037406A1 (en) * 2002-06-12 2005-02-17 De La Torre-Bueno Jose Methods and apparatus for analysis of a biological specimen
US7272252B2 (en) * 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
JP2004163413A (ja) * 2002-08-28 2004-06-10 Carl-Zeiss-Stiftung Trading As Carl Zeiss 顕微鏡システムおよび顕微鏡検査方法
WO2004029221A2 (en) 2002-09-27 2004-04-08 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US9487823B2 (en) * 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US8043834B2 (en) * 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
US20040202357A1 (en) 2003-04-11 2004-10-14 Perz Cynthia B. Silhouette image acquisition
CA2529285A1 (en) * 2003-06-13 2004-12-29 The General Hospital Corporation Microfluidic systems for size based removal of red blood cells and platelets from blood
US20050009032A1 (en) * 2003-07-07 2005-01-13 Cytokinetics, Inc. Methods and apparatus for characterising cells and treatments
US20050014217A1 (en) 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
WO2005010677A2 (en) * 2003-07-18 2005-02-03 Cytokinetics, Inc. Characterizing biological stimuli by response curves
US7235353B2 (en) 2003-07-18 2007-06-26 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
US7251363B2 (en) * 2003-07-29 2007-07-31 Ventana Medical Systems, Inc. Method and system for creating an image mask
US7440101B2 (en) 2004-01-23 2008-10-21 Beckman Coulter, Inc. System and method for multiple laser triggering
JP4271054B2 (ja) * 2004-02-12 2009-06-03 オリンパス株式会社 細胞画像解析装置
US20050273271A1 (en) * 2004-04-05 2005-12-08 Aibing Rao Method of characterizing cell shape
WO2005119575A2 (en) 2004-05-27 2005-12-15 Aperio Technologies, Inc Systems and methods for creating and viewing three dimensional virtual slides
US7653260B2 (en) * 2004-06-17 2010-01-26 Carl Zeis MicroImaging GmbH System and method of registering field of view
US8582924B2 (en) * 2004-06-30 2013-11-12 Carl Zeiss Microimaging Gmbh Data structure of an image storage and retrieval system
US7323318B2 (en) * 2004-07-15 2008-01-29 Cytokinetics, Inc. Assay for distinguishing live and dead cells
US20070031818A1 (en) * 2004-07-15 2007-02-08 Cytokinetics, Inc., A Delaware Corporation Assay for distinguishing live and dead cells
US7612769B2 (en) * 2004-09-14 2009-11-03 E.I. Du Pont De Nemours And Company Computer-implemented methods for organizing image data produced by resonant Mie scattering of light from microparticles and resulting data structures
JP2008518587A (ja) * 2004-09-22 2008-06-05 アイコニシス インコーポレーテッド 多細胞下成分の検出及び定量法
EP1863908B1 (de) * 2005-04-01 2010-11-17 Qiagen GmbH Reverse transkription und amplifikation von rna bei simultaner degradierung von dna
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8164622B2 (en) 2005-07-01 2012-04-24 Aperio Technologies, Inc. System and method for single optical axis multi-detector microscope slide scanner
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20070031043A1 (en) * 2005-08-02 2007-02-08 Perz Cynthia B System for and method of intelligently directed segmentation analysis for automated microscope systems
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
US9133506B2 (en) * 2006-01-10 2015-09-15 Applied Spectral Imaging Ltd. Methods and systems for analyzing biological samples
DE102006020885A1 (de) * 2006-05-05 2007-11-08 Qiagen Gmbh Einführung von Sequenzelementen in Nukleinsäuren
EP2034349B2 (de) 2006-06-08 2023-07-19 Nikon Corporation Beobachtungsvorrichtung und beobachtungsverfahren
JP4678601B2 (ja) * 2006-08-15 2011-04-27 横河電機株式会社 創薬スクリーニング装置
EA022609B1 (ru) * 2007-02-12 2016-02-29 А1М Фарма Аб Применение свободного фетального гемоглобина в качестве маркера преэклампсии
DK2156370T3 (da) * 2007-05-14 2012-01-23 Historx Inc Kompartmentadskillelse ved pixelkarakterisering under anvendelse af billeddata-clustering
EP2162728B1 (de) * 2007-06-15 2016-07-27 Novartis AG Mikroskopisches system und verfahren zur erfassung von standardisierten daten
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) * 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
US7936913B2 (en) * 2007-08-07 2011-05-03 Nextslide Imaging Llc Network image review in clinical hematology
WO2009029810A1 (en) * 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
DE102007062067A1 (de) * 2007-12-21 2009-07-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optisches Verfahren und Vorrichtung zur Klassifizierung von Partikeln
EP2255310B1 (de) 2008-02-29 2019-02-20 Dako Denmark A/S Systeme und verfahren zur ortung und bereitstellung von arbeitsflussinformationen
WO2009117683A2 (en) * 2008-03-21 2009-09-24 Abbott Point Of Care Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
EP2271935B1 (de) 2008-04-11 2012-10-03 Universität Leipzig Verfahren und kit zur ex-vivo-beurteilung der reaktion eines tumors auf zu testende bedingungen
JP5407015B2 (ja) * 2008-07-10 2014-02-05 国立大学法人徳島大学 画像処理装置、画像処理方法、コンピュータ実行可能な画像処理プログラム、及び顕微鏡システム
WO2010012002A1 (en) * 2008-07-25 2010-01-28 Saryna Medical Corporation Methods and systems for genetic analysis of fetal nucleated red blood cells
ES2573945T3 (es) * 2008-09-16 2016-06-13 Novartis Ag Cuantificación reproducible de expresión de biomarcadores
EP3764085A3 (de) 2008-10-24 2021-03-24 Leica Biosystems Imaging Inc. Fluoreszenz-scanner mit komplettobjektträger
JP4997255B2 (ja) * 2009-01-05 2012-08-08 オリンパス株式会社 細胞画像解析装置
FR2942899B1 (fr) * 2009-03-03 2011-09-23 Jose Balbuena Dispositif et procede d'analyse optique de documents
US8187979B2 (en) * 2009-12-23 2012-05-29 Varian Semiconductor Equipment Associates, Inc. Workpiece patterning with plasma sheath modulation
AU2011208382B2 (en) 2010-01-21 2015-02-26 Biocep Ltd. Magnetic separation of rare cells
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
JP5495934B2 (ja) * 2010-05-18 2014-05-21 キヤノン株式会社 画像処理装置、その処理方法及びプログラム
EP2601523B1 (de) * 2010-08-05 2018-06-06 Abbott Point Of Care, Inc. Verfahren und vorrichtung für automatisierte vollblutprobenanalysen aus mikroskopiebildern
JP5668436B2 (ja) * 2010-12-01 2015-02-12 ソニー株式会社 検体領域検出方法、検体領域検出装置及び検体領域検出プログラム
AU2012242587B2 (en) 2011-04-15 2015-11-26 Roche Diagnostics Hematology, Inc. Measuring volume and constituents of cells
JP5413408B2 (ja) * 2011-06-09 2014-02-12 富士ゼロックス株式会社 画像処理装置、プログラム及び画像処理システム
EP2725341A4 (de) 2011-06-27 2015-02-25 Sysmex Corp Zellanalysator
EP2840380A4 (de) * 2012-04-18 2015-11-25 Olympus Corp Einzelpartikeldetektor mit photoanalysis, einzelpartikelnachweisverfahren und computerprogramm für einzelpartikelnachweis
WO2014164757A1 (en) * 2013-03-11 2014-10-09 Roche Diagnostics Hematology, Inc. Imaging blood cells
JP6128998B2 (ja) * 2013-07-09 2017-05-17 富士フイルム株式会社 遺伝毒性又は骨髄毒性評価方法及び遺伝毒性又は骨髄毒性評価キット
WO2015013605A1 (en) * 2013-07-26 2015-01-29 Abbott Point Of Care, Inc. Method and apparatus for producing an image of undiluted whole blood sample having wright stain coloration
CN106536759A (zh) * 2014-08-05 2017-03-22 富士胶片株式会社 胎儿染色体的检查方法
WO2016138064A1 (en) * 2015-02-24 2016-09-01 Nanoscopia (Cayman), Inc. Off-axis dark field and fluorescence illumination
DE102016109945A1 (de) 2015-11-05 2017-05-11 Leica Microsystems Cms Gmbh Mikroskop für die Durchlicht- und Fluoreszenzmikroskopie
US10255511B2 (en) * 2016-01-04 2019-04-09 Texas Instruments Incorporated Real time traffic sign recognition
US10324041B2 (en) 2016-12-21 2019-06-18 Abbott Japan Co., Ltd. Optical imaging system using lateral illumination for digital assays
US11047854B2 (en) 2017-02-06 2021-06-29 Abbott Japan Llc Methods for reducing noise in signal-generating digital assays
DE102017107348B4 (de) * 2017-04-05 2019-03-14 Olympus Soft Imaging Solutions Gmbh Verfahren zur zytometrischen Analyse von Zellproben
CN110914674B (zh) * 2017-04-28 2023-02-24 迈克维斯公司 用于量化活生物体的方法和器件以及器件的使用
US20210199582A1 (en) * 2018-06-28 2021-07-01 The Regents Of The University Of California Producing a composite image of a stained tissue sample by combining image data obtained through brightfield and fluorescence imaging modes
WO2020039520A1 (ja) * 2018-08-22 2020-02-27 オリンパス株式会社 画像処理装置、撮像システム、画像処理装置の作動方法、及び画像処理装置の作動プログラム
EP3644044B1 (de) 2018-10-24 2020-12-23 Leica Biosystems Imaging, Inc. Kamerabelichtungssteuerung bei der erfassung von fluoreszenz-in-situ-hybridisierungs-bildern
CN113574361A (zh) * 2019-03-27 2021-10-29 贝克顿·迪金森公司 基于频率编码图像对细胞进行分选的系统及其使用方法
EP4038370A4 (de) * 2019-10-03 2023-10-11 The Regents of the University of California Fluoreszenzimitierende hellfeldbildgebung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125828A (en) * 1972-08-04 1978-11-14 Med-El Inc. Method and apparatus for automated classification and analysis of cells
US3999047A (en) * 1972-09-05 1976-12-21 Green James E Method and apparatus utilizing color algebra for analyzing scene regions
US5093866A (en) 1990-02-09 1992-03-03 Hamilton Equine Associates Limited Fluorescence and motility characterization system for cells, bacteria, and particles in fluids
US5162990A (en) 1990-06-15 1992-11-10 The United States Of America As Represented By The United States Navy System and method for quantifying macrophage phagocytosis by computer image analysis
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
GB9215710D0 (en) 1992-07-23 1992-09-09 Inst Of Cancer The Research Analysis of cells
US5294799A (en) 1993-02-01 1994-03-15 Aslund Nils R D Apparatus for quantitative imaging of multiple fluorophores
US5432054A (en) 1994-01-31 1995-07-11 Applied Imaging Method for separating rare cells from a population of cells
US5662813A (en) * 1994-10-21 1997-09-02 Bioseparations, Inc. Method for separation of nucleated fetal erythrocytes from maternal blood samples
US5863504A (en) 1995-03-16 1999-01-26 Bio-Rad Laboratories, Inc. Fluorescence imaging instrument utilizing fish
US5642433A (en) 1995-07-31 1997-06-24 Neopath, Inc. Method and apparatus for image contrast quality evaluation
US5764792A (en) 1996-01-19 1998-06-09 Oncor, Inc. Method and apparatus for processing images
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening

Also Published As

Publication number Publication date
EP0981732A1 (de) 2000-03-01
CA2289930C (en) 2007-08-07
NO995542D0 (no) 1999-11-12
US6169816B1 (en) 2001-01-02
ATE308747T1 (de) 2005-11-15
DE69832167T2 (de) 2006-07-20
IL132747A0 (en) 2001-03-19
AU739834B2 (en) 2001-10-18
CA2289930A1 (en) 1998-11-19
IL132747A (en) 2002-12-01
AU7482898A (en) 1998-12-08
JP2002514304A (ja) 2002-05-14
NO995542L (no) 2000-01-14
EP0981732B1 (de) 2005-11-02
HK1029170A1 (en) 2001-03-23
WO1998052018A1 (en) 1998-11-19

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Owner name: GENETIX CORP., SANTA CLARA, CALIF., US