DE69832115D1 - Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbarer Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung - Google Patents

Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbarer Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung

Info

Publication number
DE69832115D1
DE69832115D1 DE69832115T DE69832115T DE69832115D1 DE 69832115 D1 DE69832115 D1 DE 69832115D1 DE 69832115 T DE69832115 T DE 69832115T DE 69832115 T DE69832115 T DE 69832115T DE 69832115 D1 DE69832115 D1 DE 69832115D1
Authority
DE
Germany
Prior art keywords
aqueous solution
stabilizing
stabilized
carboxylic acid
containing aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69832115T
Other languages
English (en)
Other versions
DE69832115T2 (de
Inventor
Sawa Shirou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of DE69832115D1 publication Critical patent/DE69832115D1/de
Application granted granted Critical
Publication of DE69832115T2 publication Critical patent/DE69832115T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0046Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69832115T 1997-02-04 1998-02-03 Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbarer Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung Expired - Lifetime DE69832115T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2180597 1997-02-04
JP2180597 1997-02-04

Publications (2)

Publication Number Publication Date
DE69832115D1 true DE69832115D1 (de) 2005-12-01
DE69832115T2 DE69832115T2 (de) 2006-07-13

Family

ID=12065276

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69819569T Expired - Lifetime DE69819569D1 (de) 1997-02-04 1998-02-03 Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbaren Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung
DE69832115T Expired - Lifetime DE69832115T2 (de) 1997-02-04 1998-02-03 Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbarer Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69819569T Expired - Lifetime DE69819569D1 (de) 1997-02-04 1998-02-03 Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbaren Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung

Country Status (7)

Country Link
US (3) US6274592B1 (de)
EP (2) EP0856310B1 (de)
KR (1) KR100506484B1 (de)
AT (2) ATE253891T1 (de)
CA (1) CA2228536A1 (de)
DE (2) DE69819569D1 (de)
ES (1) ES2250814T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK286420B6 (sk) 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
WO2003005969A2 (en) 2001-07-12 2003-01-23 Bristol-Myers Squibb Pharma Company Tetrahydropurinones as corticotropin releasing factor
CN1578781A (zh) 2001-09-26 2005-02-09 拜尔药品公司 用作抗糖尿病药物的1,8-萘啶衍生物
PT1586316E (pt) 2003-01-21 2008-05-28 Senju Pharma Co Preparação líquida aquosa contendo ácido 2-amino-3-(4- bromobenzoil)fenilacético
MX2008012488A (es) 2006-03-28 2008-10-10 Procter & Gamble Un proceso de acoplamiento para preparar intermedios de quinolona.
CA2647457C (en) 2006-03-28 2011-05-24 The Procter & Gamble Company A hydride reduction process for preparing quinolone intermediates
EP2001862B1 (de) 2006-03-28 2011-04-27 Warner Chilcott Company, LLC Malatsalze und polymorphe von (3s,5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure
CA2824433C (en) 2011-01-18 2019-11-12 Senju Pharmaceutical Co., Ltd. Aqueous liquid bromfenac composition having preservative efficacy
WO2013031935A1 (ja) * 2011-08-31 2013-03-07 興和株式会社 安定な医薬組成物
PT4426434T (pt) 2021-11-02 2025-11-24 Flare Therapeutics Inc Agonistas inversos de pparg e suas utilizações
WO2023205463A1 (en) 2022-04-22 2023-10-26 Vertex Pharmaceuticals Incorporated Heteroaryl compounds for the treatment of pain

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB873526A (en) 1957-08-14 1961-07-26 Upjohn Co Fluid compositions comprising (acetyl-salicylic acid)-anhydride
US4339428A (en) 1980-08-18 1982-07-13 Bristol-Myers Company Capsule product containing high dosage of aspirin in powder or granulated form and alkaline tablet or pellet comprising magnesium carbonate, calcium carbonate and a magnesium dry component
US4559343A (en) 1982-09-07 1985-12-17 Alcon Laboratories, Inc. Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents
EP0173729B1 (de) 1984-03-14 1990-10-17 Jérôme CORBIERE Verfahren zum lösen von wirksubstanzen und auf diese weise erhaltene arzneimittel
IL80459A (en) 1986-10-30 1991-04-15 Abic Ltd Water-soluble adduct of norfloxacin and nicotinic acid
IT1226940B (it) 1988-09-16 1991-02-22 Recordati Chem Pharm Sistema terapeutico a rilascio controllato per formulazioni farmaceutiche liquide
CA1336687C (en) 1989-08-23 1995-08-15 Thomas M. Tencza Process for preparing tablets containing ibuprofen, apap and caffeine, the products of this process and the use of such products
US5296228A (en) 1992-03-13 1994-03-22 Allergan, Inc. Compositions for controlled delivery of pharmaceutical compounds
ES2065846B1 (es) * 1993-04-20 1995-10-01 Cusi Lab Formulacion farmaceutica a base de un agente antiinflamatorio esteroidico o no esteroidico y un antibiotico pertenciente al grupo de los inhibidores de la adn girasa para su utilizacion topica oftalmica.
ATE177635T1 (de) 1993-04-22 1999-04-15 Senju Pharma Co Wässrige arzneizubereitungen enthaltend argatroban und cyclodextrin oder coffein
JPH0797325A (ja) 1993-06-30 1995-04-11 Takeda Chem Ind Ltd 安定な固形製剤およびその製造法
AU676315B2 (en) 1993-06-30 1997-03-06 Takeda Chemical Industries Ltd. Stabilized solid pharmaceutical preparation and method of producing the same
HUT72408A (en) 1993-09-10 1996-04-29 Egyt Gyogyszervegyeszeti Gyar Process for producing tablets containing acetyl-salicylic acid
US5641512A (en) 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
JP3170619B2 (ja) * 1995-04-20 2001-05-28 参天製薬株式会社 有機アミンを配合したプラノプロフェン点眼液
JPH08333246A (ja) 1995-06-07 1996-12-17 Taisho Pharmaceut Co Ltd イブプロフェン懸濁液剤
JPH08333265A (ja) 1995-06-07 1996-12-17 Taisho Pharmaceut Co Ltd イブプロフェン懸濁液剤
JP3382076B2 (ja) 1995-12-12 2003-03-04 佐藤製薬株式会社 イブプロフェンを溶解してなるかぜ薬軟カプセル及びその製造方法
GB9613457D0 (en) 1996-06-27 1996-08-28 Procter & Gamble Pharmaceutical compositions
US5942508A (en) * 1997-02-04 1999-08-24 Senju Pharmaceutical Co., Ltd. Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid

Also Published As

Publication number Publication date
US7320985B2 (en) 2008-01-22
ES2250814T3 (es) 2006-04-16
EP0856310A2 (de) 1998-08-05
EP1389469B1 (de) 2005-10-26
CA2228536A1 (en) 1998-08-04
US6274592B1 (en) 2001-08-14
ATE253891T1 (de) 2003-11-15
DE69819569D1 (de) 2003-12-18
EP1389469A1 (de) 2004-02-18
US20010056098A1 (en) 2001-12-27
EP0856310A3 (de) 2000-01-19
DE69832115T2 (de) 2006-07-13
KR19980071023A (ko) 1998-10-26
EP0856310B1 (de) 2003-11-12
US20050075350A1 (en) 2005-04-07
KR100506484B1 (ko) 2005-11-16
ATE307610T1 (de) 2005-11-15

Similar Documents

Publication Publication Date Title
DE69832115D1 (de) Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbarer Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung
ATE170513T1 (de) Diastereomeres salz von optisch aktiver chinolinmevalonsäure
DK0528580T3 (da) Fremstilling af titanderivater
ID21985A (id) Garam tambahan asam senyawa piridina yang aktif secara optis dan proses pembuatannya
DE59505022D1 (de) Verfahren zur Racemisierung von Enantiomeren der alpha-Liponsäure
NO20005660L (no) Nye mellomprodukter og fremgangsmåter for fremstilling av optisk aktive oktansyrederivater
DK0637586T3 (da) 2-(Piperidin-4-yl, pyridin-4-yl og tetrahydropyridin-4-yl)-benzofuran-7-carbamatderivater, deres fremstilling og anvendelse
DK0415102T3 (da) 1,3-Dihydro-1-(pyridinylamino)-2H-indol-2-oner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
ES514463A0 (es) "procedimiento de escision enzimatica de derivados de insulina".
ATE239505T1 (de) Verfahren zum löslichmachen von pyridoncarbonsäuren mit hilfe von arylcarbonsäuren als lösungsvermittler
TW256831B (de)
EP0718281A4 (de) Cyclohexandiharnstoff-derivate und verfahren zu deren herstellung
ATE172734T1 (de) Verfahren zur herstellung von ceftriaxon
DE60038281D1 (de) Verfahren zur herstellung von optisch aktiven pyridinethanol-derivaten
DE3789409D1 (de) Verfahren zur Herstellung von Chinolin-2,3-Carbonsäure.
ATE205211T1 (de) Benzopyranopyridoncarbonsäuren und verfahren zu ihrer herstellung
ATE318517T1 (de) Eine stabilisierte isothiazolon-zusammensetzung und ein verfahren zur stabilisierung von isothiazolon
BR9405262A (pt) Processo para a preparação de um ácido piridina-2,3-dicarboxílico
ES2146420T3 (es) Procedimiento para preparar acidos carboxilicos opticamente activos.
PT83715B (pt) Processo para a preparacao de novos derivados de piperidina
ATE247084T1 (de) Verfahren zur herstellung von hydroxamsäuren
EP0928791A4 (de) Verfahren zur herstellung von 1,4-benzodioxan-derivaten
ATE282028T1 (de) Verfahren zur kontinuierlichen herstellung von basischen, cyclischen, optisch aktiven alpha- aminosäuren
DE3872133D1 (de) Verfahren zur herstellung von salzen der dimethylglycylgluconsaeure.
ATE82565T1 (de) Verfahren zur stabilisierung von waessrigen formaldehydloesungen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition