DE69831248T2 - Verfahren und zusammensetzungen zur optimierung des sauerstofftransportes in zellfreien systemen - Google Patents

Verfahren und zusammensetzungen zur optimierung des sauerstofftransportes in zellfreien systemen Download PDF

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Publication number
DE69831248T2
DE69831248T2 DE69831248T DE69831248T DE69831248T2 DE 69831248 T2 DE69831248 T2 DE 69831248T2 DE 69831248 T DE69831248 T DE 69831248T DE 69831248 T DE69831248 T DE 69831248T DE 69831248 T2 DE69831248 T2 DE 69831248T2
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DE
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Prior art keywords
hemoglobin
blood
oxygen
pentastarch
animals
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Expired - Lifetime
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DE69831248T
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German (de)
English (en)
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DE69831248D1 (de
Inventor
M. Robert WINSLOW
Marcos Intaglietta
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University of California
University of California Berkeley
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University of California
University of California Berkeley
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Priority claimed from US08/810,694 external-priority patent/US5814601A/en
Application filed by University of California, University of California Berkeley filed Critical University of California
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Publication of DE69831248D1 publication Critical patent/DE69831248D1/de
Publication of DE69831248T2 publication Critical patent/DE69831248T2/de
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Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/813Carrier is a saccharide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815Carrier is a synthetic polymer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/829Blood

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
DE69831248T 1997-02-28 1998-02-27 Verfahren und zusammensetzungen zur optimierung des sauerstofftransportes in zellfreien systemen Expired - Lifetime DE69831248T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US810694 1997-02-28
US08/810,694 US5814601A (en) 1997-02-28 1997-02-28 Methods and compositions for optimization of oxygen transport by cell-free systems
PCT/US1998/003846 WO1998037909A1 (en) 1997-02-28 1998-02-27 Methods and compositions for optimization of oxygen transport by cell-free systems
US09/032,342 US6054427A (en) 1997-02-28 1998-02-27 Methods and compositions for optimization of oxygen transport by cell-free systems
US32342 2001-12-21

Publications (2)

Publication Number Publication Date
DE69831248D1 DE69831248D1 (de) 2005-09-22
DE69831248T2 true DE69831248T2 (de) 2006-04-13

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831248T Expired - Lifetime DE69831248T2 (de) 1997-02-28 1998-02-27 Verfahren und zusammensetzungen zur optimierung des sauerstofftransportes in zellfreien systemen

Country Status (6)

Country Link
US (5) US6054427A (enExample)
EP (1) EP1011710B1 (enExample)
JP (1) JP4583510B2 (enExample)
AT (1) ATE302019T1 (enExample)
AU (1) AU735799C (enExample)
DE (1) DE69831248T2 (enExample)

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DE69831248D1 (de) 2005-09-22
EP1011710A1 (en) 2000-06-28
US6432918B1 (en) 2002-08-13
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US20050009736A1 (en) 2005-01-13
US6054427A (en) 2000-04-25
US20050239686A1 (en) 2005-10-27
US7101846B2 (en) 2006-09-05
EP1011710A4 (en) 2004-03-31
JP4583510B2 (ja) 2010-11-17
US20030083233A1 (en) 2003-05-01
AU735799C (en) 2005-04-28
ATE302019T1 (de) 2005-09-15

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