DE69523604T2 - Komplexe aus porphyrin und menschlichem serumalbumin mit der fähigkeit, sauerstoff zu binden, und deren therapeutische verwendungen - Google Patents

Komplexe aus porphyrin und menschlichem serumalbumin mit der fähigkeit, sauerstoff zu binden, und deren therapeutische verwendungen

Info

Publication number
DE69523604T2
DE69523604T2 DE69523604T DE69523604T DE69523604T2 DE 69523604 T2 DE69523604 T2 DE 69523604T2 DE 69523604 T DE69523604 T DE 69523604T DE 69523604 T DE69523604 T DE 69523604T DE 69523604 T2 DE69523604 T2 DE 69523604T2
Authority
DE
Germany
Prior art keywords
complexes
human serum
porphyrine
ability
therapeutic use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69523604T
Other languages
English (en)
Other versions
DE69523604D1 (de
Inventor
Joseph Bonaventura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Durham
Duke University
Original Assignee
University of Durham
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Durham, Duke University filed Critical University of Durham
Application granted granted Critical
Publication of DE69523604D1 publication Critical patent/DE69523604D1/de
Publication of DE69523604T2 publication Critical patent/DE69523604T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
DE69523604T 1994-07-22 1995-07-07 Komplexe aus porphyrin und menschlichem serumalbumin mit der fähigkeit, sauerstoff zu binden, und deren therapeutische verwendungen Expired - Fee Related DE69523604T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27937194A 1994-07-22 1994-07-22
PCT/US1995/008479 WO1996003426A1 (en) 1994-07-22 1995-07-07 Human serum albumin-porphyrin complexes with the ability to bind oxygen and therapeutic uses thereof

Publications (2)

Publication Number Publication Date
DE69523604D1 DE69523604D1 (de) 2001-12-06
DE69523604T2 true DE69523604T2 (de) 2002-04-25

Family

ID=23068674

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69523604T Expired - Fee Related DE69523604T2 (de) 1994-07-22 1995-07-07 Komplexe aus porphyrin und menschlichem serumalbumin mit der fähigkeit, sauerstoff zu binden, und deren therapeutische verwendungen

Country Status (8)

Country Link
US (1) US5773417A (de)
EP (1) EP0775157B1 (de)
JP (1) JPH10503489A (de)
AT (1) ATE207932T1 (de)
AU (1) AU685661B2 (de)
CA (1) CA2195630A1 (de)
DE (1) DE69523604T2 (de)
WO (1) WO1996003426A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3428225B2 (ja) * 1995-04-28 2003-07-22 三菱ウェルファーマ株式会社 ポルフィリン金属錯体−アルブミン包接化合物及び酸素運搬体
US5948609A (en) * 1997-12-03 1999-09-07 Carter; Daniel C. Oxygen-transporting albumin-based blood replacement composition and blood volume expander
EP1295602A1 (de) * 2000-06-29 2003-03-26 Rohto Pharmaceutical Co., Ltd. Sauerstoffhaltige ophthalmische verbindung
WO2003003975A2 (en) 2001-06-04 2003-01-16 The General Hospital Corporation Detection and therapy of vulnerable plaque with photodynamic compounds
JP3816767B2 (ja) 2001-07-30 2006-08-30 独立行政法人科学技術振興機構 ポルフィリン金属錯体とそれを含有する酸素輸液
GB2397067B (en) * 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
EP1538151B1 (de) * 2003-08-28 2006-10-18 Nipro Corporation Künstlicher Sauerstoffträger und Herstellungsverfahren dafür
GB0424294D0 (en) * 2004-11-03 2004-12-01 Elam T Ltd Buffer layer
US20060217291A1 (en) * 2005-03-25 2006-09-28 Ichiro Hirotsu Radiosensitizer
JP4665791B2 (ja) 2005-04-15 2011-04-06 ニプロ株式会社 酸素運搬体の脱一酸化炭素化方法、脱一酸化炭素化された酸素運搬体、その医薬組成物及び脱一酸化炭素化装置
US20090275732A1 (en) * 2005-05-12 2009-11-05 Ichiro Hirotsu Agent for improving circulatory disorder
EP2615108B1 (de) 2006-09-08 2016-10-26 Ambrx, Inc. Modifiziertes humanes Plasmapolypeptid oder Fc-Gerüste und deren Verwendungen
MX2019010241A (es) * 2017-03-01 2019-12-02 Metronom Health Inc Sensores de analitos y metodos de fabricacion de sensores de analitos.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55144048A (en) * 1979-04-27 1980-11-10 Hidetoshi Tsuchida Coordination high polymeric metal complex composition for adsorption-desorption of oxygen
JPS5925767B2 (ja) * 1981-06-10 1984-06-21 森六株式会社 鉄（２）ポルフィリン錯体を包接したリン脂質リポリ−ムおよび酸素吸脱着剤
JPS5925766B2 (ja) * 1981-07-09 1984-06-21 森六株式会社 鉄（２）ポルフィリン錯体を包接した界面活性剤ミセルおよび酸素吸脱着剤
JPS58213779A (ja) * 1982-06-07 1983-12-12 Hidetoshi Tsuchida 疎水性アルキル基を有する鉄−テトラフエニルポルフイン錯体及び酸素吸脱着剤
JPH03128321A (ja) * 1989-06-12 1991-05-31 Res Inst For Prod Dev 人工酸素運搬体
US5240800A (en) * 1991-07-29 1993-08-31 Eastman Kodak Company Near-infrared radiation sensitive photoelectrographic master and imaging method
EP0601183A4 (de) * 1991-08-02 1996-12-04 Meiji Milk Prod Co Ltd Anti-hiv medikament.
US5349054A (en) * 1991-08-15 1994-09-20 Duke University Activated benzenepentacarboxylate-crosslinked low oxygen affinity hemoglobin
US5334705A (en) * 1991-08-15 1994-08-02 Duke University Benzenetricarboxylate derivative-crosslinked low oxygen affinity hemoglobin
US5296466A (en) * 1992-02-19 1994-03-22 Board Of Regents, The University Of Texas System Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein
WO1994015628A1 (en) * 1993-01-12 1994-07-21 The Trustees Of The University Of Pennsylvania Electrically conducting synthetic peptide complexes

Also Published As

Publication number Publication date
EP0775157B1 (de) 2001-10-31
CA2195630A1 (en) 1996-02-08
AU3093795A (en) 1996-02-22
EP0775157A1 (de) 1997-05-28
EP0775157A4 (de) 1997-09-24
AU685661B2 (en) 1998-01-22
JPH10503489A (ja) 1998-03-31
DE69523604D1 (de) 2001-12-06
US5773417A (en) 1998-06-30
WO1996003426A1 (en) 1996-02-08
ATE207932T1 (de) 2001-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee