DE69826994T2 - Bioabbaubare Terephthalat Polyester-Polyphosphat Polymere, Zusammensetzungen, Gegenstände und Verfahren für ihre Herstellung und Verwendung - Google Patents

Bioabbaubare Terephthalat Polyester-Polyphosphat Polymere, Zusammensetzungen, Gegenstände und Verfahren für ihre Herstellung und Verwendung Download PDF

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Publication number
DE69826994T2
DE69826994T2 DE1998626994 DE69826994T DE69826994T2 DE 69826994 T2 DE69826994 T2 DE 69826994T2 DE 1998626994 DE1998626994 DE 1998626994 DE 69826994 T DE69826994 T DE 69826994T DE 69826994 T2 DE69826994 T2 DE 69826994T2
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DE
Germany
Prior art keywords
polymer
article
biologically active
agents
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1998626994
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German (de)
English (en)
Other versions
DE69826994D1 (de
Inventor
Hai-Quan Mao
W. Kam LEONG
Wenbin Dang
Hungnan Lo
Zhong Zhao
P. David NOWOTNIK
P. James ENGLISH
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Eisai Inc
Original Assignee
Guilford Pharmaceuticals Inc
Johns Hopkins University
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Publication date
Application filed by Guilford Pharmaceuticals Inc, Johns Hopkins University filed Critical Guilford Pharmaceuticals Inc
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Publication of DE69826994T2 publication Critical patent/DE69826994T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
    • C08G63/692—Polyesters containing atoms other than carbon, hydrogen and oxygen containing phosphorus
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
    • C08G63/692—Polyesters containing atoms other than carbon, hydrogen and oxygen containing phosphorus
    • C08G63/6924—Polyesters containing atoms other than carbon, hydrogen and oxygen containing phosphorus derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/6926—Dicarboxylic acids and dihydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L85/00—Compositions of macromolecular compounds obtained by reactions forming a linkage in the main chain of the macromolecule containing atoms other than silicon, sulfur, nitrogen, oxygen and carbon; Compositions of derivatives of such polymers
    • C08L85/02—Compositions of macromolecular compounds obtained by reactions forming a linkage in the main chain of the macromolecule containing atoms other than silicon, sulfur, nitrogen, oxygen and carbon; Compositions of derivatives of such polymers containing phosphorus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2933—Coated or with bond, impregnation or core
    • Y10T428/2938—Coating on discrete and individual rods, strands or filaments
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/30—Woven fabric [i.e., woven strand or strip material]
    • Y10T442/3472—Woven fabric including an additional woven fabric layer
    • Y10T442/3528—Three or more fabric layers
    • Y10T442/3545—Woven fabric layers impregnated with a blend of thermosetting and thermoplastic resins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
DE1998626994 1997-04-03 1998-04-02 Bioabbaubare Terephthalat Polyester-Polyphosphat Polymere, Zusammensetzungen, Gegenstände und Verfahren für ihre Herstellung und Verwendung Expired - Lifetime DE69826994T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83221597A 1997-04-03 1997-04-03
US832215 1997-04-03
PCT/US1998/006381 WO1998044021A1 (en) 1997-04-03 1998-04-02 Biodegradable terephthalate polyester-poly(phosphate) polymers, compositions, articles, and methods for making and using the same

Publications (2)

Publication Number Publication Date
DE69826994D1 DE69826994D1 (de) 2004-11-18
DE69826994T2 true DE69826994T2 (de) 2005-12-08

Family

ID=25261011

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1998626994 Expired - Lifetime DE69826994T2 (de) 1997-04-03 1998-04-02 Bioabbaubare Terephthalat Polyester-Polyphosphat Polymere, Zusammensetzungen, Gegenstände und Verfahren für ihre Herstellung und Verwendung

Country Status (16)

Country Link
US (2) US6322797B1 (enExample)
EP (1) EP0973818B1 (enExample)
JP (1) JP4496316B2 (enExample)
KR (1) KR20010006026A (enExample)
CN (1) CN1256700A (enExample)
AT (1) ATE279461T1 (enExample)
AU (1) AU741145B2 (enExample)
BR (1) BR9809064A (enExample)
CA (1) CA2285903A1 (enExample)
DE (1) DE69826994T2 (enExample)
HU (1) HUP0001256A3 (enExample)
IL (1) IL132120A0 (enExample)
NO (1) NO994802L (enExample)
NZ (1) NZ500649A (enExample)
TW (1) TW534915B (enExample)
WO (1) WO1998044021A1 (enExample)

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ATE279461T1 (de) 2004-10-15
AU741145B2 (en) 2001-11-22
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WO1998044021A1 (en) 1998-10-08
NO994802D0 (no) 1999-10-01
JP2001519842A (ja) 2001-10-23
HUP0001256A3 (en) 2002-12-28
DE69826994D1 (de) 2004-11-18
AU6945098A (en) 1998-10-22
CN1256700A (zh) 2000-06-14
NO994802L (no) 1999-12-03
WO1998044021A9 (en) 1999-04-22
US20020091230A1 (en) 2002-07-11
BR9809064A (pt) 2002-01-02
HUP0001256A2 (hu) 2002-01-28
EP0973818B1 (en) 2004-10-13
US6600010B2 (en) 2003-07-29
JP4496316B2 (ja) 2010-07-07
IL132120A0 (en) 2001-03-19
KR20010006026A (ko) 2001-01-15
US6322797B1 (en) 2001-11-27
EP0973818A1 (en) 2000-01-26
NZ500649A (en) 2001-05-25
CA2285903A1 (en) 1998-10-08

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